Rock Springs Capital Management LP

Q1 2026 13F-HR Holdings

Location
Baltimore, MD
Holdings as of
3/31/2026
Date filed
5/15/2026
Form type
13F-HR
Num holdings
100
Total value ($000)
$1,696,654
Net value change ($000)
-253,550 (-13.0%)
New positions
11
Sold out positions
7
Turnover %
10.2%
Sector allocation + QoQ delta (equities-only)
Prev filing: 2/17/2026 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q4 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
ELVN 20,104 163.5%
MMED 15,741 NEW
MIRM 14,733 24.5%
ERAS 14,314 404.4%
RVMD 11,266 10.6%
XENE 9,061 25.7%
ACLX 8,428 76.1%
MDGL 8,208 10.1%
PTCT 6,323 134.5%
INDV 6,096 NEW
Top Reduces (Value $000, Stocks/ETFs)
EXAS -61,119 -100.0%
CDTX -45,256 -100.0%
TVTX -40,546 -48.0%
FOLD -27,177 -98.9%
XBI -23,236 -85.8%
LLY -22,490 -19.9%
GPCR -21,182 -40.7%
ARGX -14,898 -17.2%
RYTM -14,407 -19.4%
IRTC -10,806 -25.9%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type