GREAT POINT PARTNERS LLC

Q1 2026 13F-HR Holdings

Location
Greenwich, CT
Holdings as of
3/31/2026
Date filed
5/15/2026
Form type
13F-HR
Num holdings
42
Total value ($000)
$435,118
Net value change ($000)
+126,704 (41.1%)
New positions
18
Sold out positions
8
Turnover %
61.1%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Snapshot: Change Analysis

Compared to Q4 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
SLGL 21,735 NEW
ALMS 18,859 NEW
DRUG 16,053 NEW
NKTR 13,859 155.5%
ANNX 13,850 NEW
VOR 13,299 74.2%
ZBIO 10,245 NEW
MLTX 9,320 NEW
VERA 8,020 NEW
LBRX 7,398 NEW
Top Reduces (Value $000, Stocks/ETFs)
IRON -19,853 -100.0%
RAPT -19,685 -100.0%
SLNO -18,520 -100.0%
DNTH -14,424 -100.0%
FULC -9,048 -100.0%
UPB -8,145 -100.0%
RARE -6,900 -100.0%
IMVT -5,512 -28.9%
SANA -2,849 -100.0%
CGEM -2,299 -35.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 26,848 (6.2% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type