Rock Springs Capital Management LP

Q2 2026 13F-HR Holdings

Location
Baltimore, MD
Holdings as of
6/30/2026
Date filed
8/14/2026
Form type
13F-HR
Num holdings
104
Total value ($000)
$2,048,808
Net value change ($000)
+352,154 (20.8%)
New positions
17
Sold out positions
13
Turnover %
12.8%
Sector allocation + QoQ delta (equities-only)
Prev filing: 5/15/2026 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q1 2026
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
RVMD 89,364 76.0%
TVTX 79,883 181.9%
Ascendis Pharma AS 45,009 NEW
LLY 27,603 30.4%
AGL 26,088 1268.3%
AVALYN PHARMACEUTICALS INC 21,823 NEW
HEMAB THERAPEUTICS HLDGS INC 21,136 NEW
MIRM 18,492 24.7%
RYTM 16,912 28.2%
PARABILIS MEDICINES INC 15,821 NEW
Top Reduces (Value $000, Stocks/ETFs)
ASND -44,374 -100.0%
ARGX -22,990 -32.0%
ACLX -19,503 -100.0%
CNTA -13,975 -100.0%
INSM -12,782 -24.9%
BSX -9,779 -30.2%
CMPX -9,765 -55.8%
ELVN -8,819 -27.2%
SLNO -8,613 -100.0%
REGN -7,804 -100.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type