HighVista Strategies LLC

Q3 2026 13F-HR Holdings

Location
Boston, MA
Holdings as of
9/30/2026
Date filed
11/13/2026
Form type
13F-HR
Num holdings
136
Total value ($000)
$380,873
Net value change ($000)
-57,726 (-13.2%)
New positions
24
Sold out positions
35
Turnover %
26.4%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Prev filing: 8/14/2026 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q2 2026
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
GMAB 8,066 NEW
MANE 6,575 NEW
DBC 5,984 21.2%
CTNM 2,923 NEW
UNP 2,880 NEW
UAL 2,851 NEW
EDIT 2,845 NEW
EWTX 2,825 76.4%
RBLX 2,763 NEW
VRDN 2,676 91.1%
Top Reduces (Value $000, Stocks/ETFs)
DFTX -7,273 -63.7%
PRAX -6,884 -68.1%
ABVX -6,443 -42.8%
LQDA -6,090 -78.0%
ALMS -5,627 -100.0%
CYTK -4,761 -71.6%
IMVT -3,749 -35.0%
MAZE -3,542 -86.9%
CCCC -3,388 -53.8%
RVMD -3,124 -24.9%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type