HighVista Strategies LLC

Q3 2026 13F-HR Detailed Holdings

Location
Boston, MA
Holdings as of
9/30/2026
Date filed
11/13/2026
Form type
13F-HR
Num holdings
136
Total value ($000)
$380,873
Net value change ($000)
-57,726 (-13.2%)
New positions
24
Sold out positions
35
Turnover %
26.4%
Sector allocation + QoQ delta (equities-only)

Holdings broken out by other managers reported in the original SEC filing. View aggregated holdings

Prev filing: 8/14/2026 Next filing: — SEC filing
You are on the SEC detailed breakdown page. Rows are shown as reported in the filing (including other manager, discretion, and voting authority fields), and are not merged like the standard holdings view. Switch to aggregated holdings.

Snapshot: Change Analysis

Compared to Q2 2026
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
GMAB 8,066 NEW
MANE 6,575 NEW
DBC 5,984 21.2%
CTNM 2,923 NEW
UNP 2,880 NEW
UAL 2,851 NEW
EDIT 2,845 NEW
EWTX 2,825 76.4%
RBLX 2,763 NEW
VRDN 2,676 91.1%
Top Reduces (Value $000, Stocks/ETFs)
DFTX -7,273 -63.7%
PRAX -6,884 -68.1%
ABVX -6,443 -42.8%
LQDA -6,090 -78.0%
ALMS -5,627 -100.0%
CYTK -4,761 -71.6%
IMVT -3,749 -35.0%
MAZE -3,542 -86.9%
CCCC -3,388 -53.8%
RVMD -3,124 -24.9%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type Discretion Other Manager Sole Shared None

Other Managers

Num Name File Number
1 HighVista Private Capital Management LLC
2 HighVista SBIC Capital Management LLC