DEERFIELD MANAGEMENT COMPANY, L.P.

Q3 2025 13F-HR Holdings

Location
New York, NY
Holdings as of
9/30/2025
Date filed
11/14/2025
Form type
13F-HR
Num holdings
152
Total value ($000)
$6,550,740
Net value change ($000)
+1,040,931 (18.9%)
New positions
47
Sold out positions
19
Turnover %
15.3%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Prev filing: 8/14/2025 Next filing: 2/17/2026 SEC filing

Snapshot: Change Analysis

Compared to Q2 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
NUVL 183,149 13.3%
CNC 149,859 86.7%
IONS 129,510 NEW
COGT 111,046 585.8%
Merus N.V. 108,836 61.1%
BMY 105,433 NEW
INSP 59,571 327.9%
BBOT 56,573 NEW
BCRX 50,323 119.7%
RVMD 45,971 36.9%
Top Reduces (Value $000, Stocks/ETFs)
OSCR -249,767 -100.0%
SPRY -94,280 -55.6%
BAX -57,258 -98.3%
MRNA -27,590 -100.0%
IDYA -23,716 -28.8%
PFE -20,203 -19.4%
LQDA -20,145 -100.0%
MREO -18,185 -100.0%
ALNY -16,305 -34.5%
NVCR -14,687 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 25,830 (0.4% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type