IONIS PHARMACEUTICALS INC - IONS

Sector: Healthcare · Industry: Pharmaceutical Preparations
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Quarter snapshot

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Q4 2025 · Q3 2025
Value (USD)
Total reported value ($000)
$13.45B
QoQ value delta ($000)
+$2.43B (+22.05%)
Implied price effect (QoQ)
+25.85%
Shares
Total shares
170,074,150
QoQ shares delta
-5,292,022 (-3.02%)
Total shares held by funds (by quarter)

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Top holders (Q4 2025)

Top 25 only Full list
Early Q1 2026 data: only 1 institutional holders reported so far. More will appear as funds file with the SEC.
Manager Value ($000) Shares % of 13F
FMR LLC 1,904,343 24,072,101 0.1%
Capital World Investors 1,420,918 17,961,299 0.19%
VANGUARD GROUP INC 1,300,604 16,440,459 0.02%
BlackRock, Inc. 842,352 10,647,863 0.01%
T. Rowe Price Investment Management, Inc. 720,536 9,108,019 0.45%
WELLINGTON MANAGEMENT GROUP LLP 495,254 6,260,325 0.09%
Bellevue Group AG 379,901 4,802,199 7.2%
STATE STREET CORP 314,451 3,974,865 0.01%
GEODE CAPITAL MANAGEMENT, LLC 249,157 3,148,849 0.02%
TWO SIGMA ADVISERS, LP 241,452 3,052,111 0.47%
PRICE T ROWE ASSOCIATES INC /MD/ 236,370 2,987,840 0.03%
TWO SIGMA INVESTMENTS, LP 210,325 2,658,646 0.3%
Tweedy, Browne Co LLC 195,000 2,464,930 15.74%
CITADEL ADVISORS LLC 182,984 2,313,036 0.03%
JPMORGAN CHASE & CO 182,332 2,304,792 0.01%
DEERFIELD MANAGEMENT COMPANY, L.P. 156,611 1,979,669 2.0%
BAKER BROS. ADVISORS LP 141,752 1,791,841 0.83%
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 139,447 1,762,706 2.9%
Deep Track Capital, LP 134,487 1,700,000 2.4%
AMERICAN CENTURY COMPANIES INC 127,929 1,617,106 0.06%
CHARLES SCHWAB INVESTMENT MANAGEMENT INC 121,975 1,541,841 0.02%
Pictet Asset Management Holding SA 112,476 1,418,491 0.11%
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 109,849 1,388,567 0.02%
BNP Paribas Asset Management Holding S.A. 107,029 1,352,837 0.12%
Polar Capital Holdings Plc 105,487 1,333,424 0.41%