IONIS PHARMACEUTICALS INC - IONS

Sector: Healthcare · Industry: Pharmaceutical Preparations

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Company profile

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Q1 2026 · Q4 2025

Value (USD)

Total reported value ($000)

$14.81B

QoQ value delta ($000)

+$1.361B (+10.11%)

Implied price effect (QoQ)

-4.5%

Total shares

196,121,304

QoQ shares delta

+26,037,081 (+15.31%)

Total shares held by funds (by quarter)

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Top 25 only Full list

Partial Q1 2026 data: 495 holders have filed so far. Prior holders are carried forward until their next 13F confirms a change.

Manager	Value ($000)	Shares	% of 13F
FMR LLC	1,843,957	24,556,637	0.1%
Capital World Investors	1,590,884	21,186,369	0.22%
VANGUARD GROUP INC	1,300,604	16,440,459	0.02%
BlackRock, Inc.	784,125	10,442,476	0.01%
VANGUARD PORTFOLIO MANAGEMENT LLC	586,370	7,808,902	0.03%
VANGUARD CAPITAL MANAGEMENT LLC	534,515	7,118,330	0.01%
WELLINGTON MANAGEMENT GROUP LLP	479,961	6,391,816	0.09%
T. Rowe Price Investment Management, Inc.	462,482	6,159,027	0.32%
TWO SIGMA INVESTMENTS, LP	439,849	5,857,629	0.35%
GEODE CAPITAL MANAGEMENT, LLC	305,196	3,984,332	0.02%
STATE STREET CORP	300,026	3,995,564	0.01%
ROYAL BANK OF CANADA	285,477	3,801,815	0.05%
TWO SIGMA ADVISERS, LP	241,452	3,052,111	0.47%
PRICE T ROWE ASSOCIATES INC /MD/	227,167	3,025,251	0.03%
JPMORGAN CHASE & CO	195,337	2,693,567	0.01%
Tweedy, Browne Co LLC	170,876	2,275,625	13.57%
Artisan Partners Limited Partnership	154,558	2,058,308	0.25%
BAKER BROS. ADVISORS LP	153,763	2,047,727	0.88%
DEERFIELD MANAGEMENT COMPANY, L.P.	148,653	1,979,669	1.75%
Deep Track Capital, LP	146,425	1,950,000	2.39%
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC	139,219	1,854,033	3.74%
Bellevue Group AG	136,563	1,818,665	3.25%
GOLDMAN SACHS GROUP INC	127,641	1,699,847	0.01%
AMERICAN CENTURY COMPANIES INC	124,935	1,663,803	0.06%
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	118,887	1,583,266	0.02%