RTW INVESTMENTS, LP

Q1 2022 13F-HR Detailed Holdings

Location
New York, NY
Holdings as of
3/31/2022
Date filed
5/16/2022
Form type
13F-HR
Num holdings
106
Total value ($000)
$4,831,643
Net value change ($000)
-2,016,684 (-29.4%)
New positions
2
Sold out positions
20
Turnover %
17.6%
Sector allocation + QoQ delta (equities-only)

Holdings broken out by other managers reported in the original SEC filing. View aggregated holdings

You are on the SEC detailed breakdown page. Rows are shown as reported in the filing (including other manager, discretion, and voting authority fields), and are not merged like the standard holdings view. Switch to aggregated holdings.

Snapshot: Change Analysis

Compared to Q4 2021
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
CUTERA INC 47,585 82.4%
CCCC 29,608 36.9%
PTGX 24,620 27.7%
CinCor Pharma, Inc. 24,375 NEW
2seventy bio, Inc. 20,975 NEW
RLMD 19,299 39.2%
FULC 17,000 24.9%
IMUX 14,155 86.2%
IMCR 12,951 30.4%
PMVP 11,758 17.1%
Top Reduces (Value $000, Stocks/ETFs)
SPY -422,590 -100.0%
IVERIC bio, Inc. -112,402 -100.0%
Mirati Therapeutics, Inc. -100,670 -43.9%
NTRA -95,919 -55.2%
RCKT -94,343 -27.3%
iTeos Therapeutics, Inc. -93,820 -85.6%
APLS -91,505 -97.2%
MASI -84,745 -34.1%
TMO -70,271 -24.2%
ALNY -60,194 -18.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type Discretion Other Manager Sole Shared None

Other Managers

Num Name File Number
1 RTW MASTER FUND, LTD. 028-16671
2 RTW Innovation Master Fund Ltd. 028-19525
3 RTW Venture Fund Ltd 028-19571