RTW INVESTMENTS, LP

Q4 2024 13F-HR Holdings

Location
New York, NY
Holdings as of
12/31/2024
Date filed
2/14/2025
Form type
13F-HR
Num holdings
72
Total value ($000)
$6,612,776
Net value change ($000)
-298,371 (-4.3%)
New positions
9
Sold out positions
5
Turnover %
8.9%
Sector allocation + QoQ delta (equities-only)
Prev filing: 11/14/2024 Next filing: 5/15/2025 SEC filing

Snapshot: Change Analysis

Compared to Q3 2024
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
MDGL 192,092 45.4%
VRNA 84,568 NEW
NTRA 81,301 24.7%
GMED 80,394 NEW
SYK 69,117 48.2%
TARS 66,971 59.7%
ZLAB 65,714 NEW
ARGX 59,448 16.8%
PTCT 59,441 21.7%
PEN 50,193 32.5%
Top Reduces (Value $000, Stocks/ETFs)
GERN -200,268 -100.0%
RNAM -142,855 -38.2%
DYN -121,975 -49.8%
RCKT -104,358 -31.9%
BRKR -94,963 -39.5%
MASI -82,034 -42.1%
IMTX -67,597 -59.2%
ACAD -51,075 -24.2%
GKOS -50,326 -100.0%
APGE -36,451 -22.9%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type