SPHERA FUNDS MANAGEMENT LTD.

Q2 2025 13F-HR Detailed Holdings

Location
Tel Aviv, L3
Holdings as of
6/30/2025
Date filed
8/14/2025
Form type
13F-HR
Num holdings
111
Total value ($000)
$426,140
Net value change ($000)
New positions
100
Sold out positions
0
Turnover %
100.0%
Sector allocation + QoQ delta (equities-only)

Holdings broken out by other managers reported in the original SEC filing. View aggregated holdings

You are on the SEC detailed breakdown page. Rows are shown as reported in the filing (including other manager, discretion, and voting authority fields), and are not merged like the standard holdings view. Switch to aggregated holdings.

Snapshot: Change Analysis

Compared to previous filing: —
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
TEVA 27,168
NVMI 20,870
SNDX 14,718
TSEM 11,476
CYTK 10,795
SNY 10,605
BIIB 10,391
AZN 9,438
LLY 8,996
NVDA 8,613
Top Reduces (Value $000, Stocks/ETFs)
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 43,647 (10.2% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
Filter:
Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type Discretion Other Manager Sole Shared None

Other Managers

Num Name File Number
1 Sphera Global Healthcare Management LP 028-15865
2 Sphera Global Healthcare GP Ltd. 028-15864