SPHERA FUNDS MANAGEMENT LTD.

Q2 2026 13F-HR Holdings

Location
Tel Aviv, L3
Holdings as of
6/30/2026
Date filed
8/14/2026
Form type
13F-HR
Num holdings
105
Total value ($000)
$766,540
Net value change ($000)
+136,857 (21.7%)
New positions
22
Sold out positions
17
Turnover %
26.4%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Snapshot: Change Analysis

Compared to Q1 2026
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
TEVA 16,577 48.4%
CYTK 16,117 614.2%
INSM 12,666 NEW
BMRN 10,897 137.9%
RYTM 8,927 NEW
LRCX 8,004 NEW
AMAT 7,982 NEW
IDYA 7,320 NEW
NVCT 7,042 NEW
HRMY 6,432 NEW
Top Reduces (Value $000, Stocks/ETFs)
NVMI -9,511 -41.0%
FOLD -8,725 -100.0%
CLBT -8,702 -100.0%
APLS -8,646 -100.0%
PANW -8,465 -100.0%
CAMT -8,038 -100.0%
SLNO -7,241 -100.0%
AMZN -6,652 -100.0%
AAOI -6,209 -100.0%
ENPH -5,385 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 67,715 (8.8% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type