Avidity Partners Management LP

Q3 2025 13F-HR Holdings

Location
Dallas, TX
Holdings as of
9/30/2025
Date filed
11/14/2025
Form type
13F-HR
Num holdings
43
Total value ($000)
$439,395
Net value change ($000)
-62,582 (-12.5%)
New positions
13
Sold out positions
25
Turnover %
52.5%
Sector allocation + QoQ delta (equities-only)
Prev filing: 8/14/2025 Next filing: 2/13/2026 SEC filing

Snapshot: Change Analysis

Compared to Q2 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
DNTH 93,615 288.3%
CGON 25,486 65.4%
MDT 18,153 NEW
BMY 11,618 NEW
PFE 9,336 NEW
ORKA 8,753 221.8%
Metsera, Inc. 7,352 NEW
JNJ 4,969 NEW
CI 4,785 NEW
ABBV 4,584 NEW
Top Reduces (Value $000, Stocks/ETFs)
NTRA -22,338 -66.3%
THC -18,656 -100.0%
BSX -18,524 -53.6%
DXCM -18,375 -100.0%
HNGE -16,681 -100.0%
EXAS -14,838 -78.7%
ISRG -14,726 -100.0%
RGEN -10,131 -76.5%
AXSM -9,865 -100.0%
RVMD -8,410 -100.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type