Soleus Capital Management, L.P.

Q3 2025 13F-HR Holdings

Location
Greenwich, CT
Holdings as of
9/30/2025
Date filed
11/14/2025
Form type
13F-HR
Num holdings
88
Total value ($000)
$1,986,447
Net value change ($000)
+476,336 (31.5%)
New positions
18
Sold out positions
25
Turnover %
17.5%
Sector allocation + QoQ delta (equities-only)
Prev filing: 8/15/2025 Next filing: 2/12/2026 SEC filing

Snapshot: Change Analysis

Compared to Q2 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
TGTX 58,132 72.0%
ELV 56,671 208.1%
KRYS 52,984 41.8%
INSP 39,887 282.0%
TWST 39,478 302.8%
FOLD 36,957 NEW
INDV 35,345 NEW
TERN 30,572 100.4%
MDGL 28,922 1194.6%
ANIP 27,855 841.3%
Top Reduces (Value $000, Stocks/ETFs)
STAA -36,649 -73.2%
ALNY -27,856 -80.0%
GRFS -27,142 -52.2%
UNH -26,907 -100.0%
SRDX -23,443 -100.0%
HUM -19,461 -100.0%
URGN -16,389 -54.7%
ASND -14,671 -100.0%
Theratechnologies Inc. -11,331 -100.0%
EOLS -10,613 -54.4%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 115,230 (5.8% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type