Paradigm Biocapital Advisors LP

Q1 2022 13F-HR Holdings

Location
New York, NY
Holdings as of
3/31/2022
Date filed
5/16/2022
Form type
13F-HR
Num holdings
25
Total value ($000)
$378,175
Net value change ($000)
+28,021 (8.0%)
New positions
7
Sold out positions
6
Turnover %
39.7%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q4 2021
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
INCY 18,618 NEW
Sierra Oncology, Inc. 14,396 139.4%
Horizon Therapeutics Public Ltd Co 14,334 NEW
UTHR 13,570 NEW
LEGN 12,235 68.0%
ARVN 11,011 49.9%
Global Blood Therapeutics, Inc. 10,646 46.6%
IMCR 10,329 224.7%
PRTA 9,799 NEW
ASND 8,396 28.6%
Top Reduces (Value $000, Stocks/ETFs)
Mirati Therapeutics, Inc. -30,067 -78.8%
ARENA PHARMACEUTICALS INC -23,400 -100.0%
Seagen Inc. -15,566 -100.0%
ARGX -14,725 -100.0%
ZNTL -11,985 -47.5%
INSM -10,742 -100.0%
GLPG -9,252 -100.0%
ENTA -5,646 -100.0%
VOR -1,911 -26.1%
Gracell Biotechnologies Inc. -1,469 -44.6%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
Filter:
Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type