Paradigm Biocapital Advisors LP

Q2 2022 13F-HR Holdings

Location
New York, NY
Holdings as of
6/30/2022
Date filed
8/15/2022
Form type
13F-HR
Num holdings
23
Total value ($000)
$501,530
Net value change ($000)
+123,355 (32.6%)
New positions
5
Sold out positions
7
Turnover %
30.5%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q1 2022
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
Mirati Therapeutics, Inc. 36,215 447.7%
ARGX 33,651 NEW
UTHR 24,855 183.2%
INCY 23,625 126.9%
LEGN 23,598 78.1%
Sierra Oncology, Inc. 19,343 78.2%
BCYC 17,594 NEW
Global Blood Therapeutics, Inc. 12,695 37.9%
IMCR 9,975 66.8%
TGTX 8,350 NEW
Top Reduces (Value $000, Stocks/ETFs)
IVERIC bio, Inc. -15,322 -100.0%
IOVA -15,109 -100.0%
Horizon Therapeutics Public Ltd Co -14,334 -100.0%
ZNTL -13,269 -100.0%
CCCC -11,566 -95.4%
ARVN -11,289 -34.1%
PRTA -9,799 -100.0%
KYMR -9,608 -100.0%
VRDN -8,107 -34.9%
OYST -5,724 -49.8%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type