Frazier Life Sciences Management, L.P.

Q3 2023 13F-HR Holdings

Location
Menlo Park, CA
Holdings as of
9/30/2023
Date filed
11/14/2023
Form type
13F-HR
Num holdings
52
Total value ($000)
$1,505,659
Net value change ($000)
-168,852 (-10.1%)
New positions
7
Sold out positions
4
Turnover %
21.1%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q2 2023
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
MIRM 91,668 81.3%
BBIO 37,674 110.1%
RCKT 28,748 NEW
APLS 23,358 NEW
ANTX 22,333 NEW
CRNX 21,790 85.5%
RYTM 18,625 52.1%
SVRA 15,120 NEW
SLNO 13,720 NEW
APGE 8,520 NEW
Top Reduces (Value $000, Stocks/ETFs)
CHINOOK THERAPEUTICS, INC. -166,956 -100.0%
SNDX -68,914 -88.8%
PHAT -39,932 -27.6%
ARQT -36,648 -44.3%
HilleVax, Inc. -36,583 -21.8%
NAMS -17,048 -13.2%
MORPHIC HLDG INC -15,222 -100.0%
Theseus Pharmaceuticals, Inc. -14,928 -71.2%
VRNA -13,110 -21.1%
REATA PHARMACEUTICALS INC -10,240 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 1,566 (0.1% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type