Frazier Life Sciences Management, L.P.

Q1 2024 13F-HR Holdings

Location
Palo Alto, CA
Holdings as of
3/31/2024
Date filed
5/15/2024
Form type
13F-HR
Num holdings
50
Total value ($000)
$2,369,981
Net value change ($000)
+499,632 (26.7%)
New positions
7
Sold out positions
6
Turnover %
7.8%
Sector allocation + QoQ delta (equities-only)
Prev filing: 2/14/2024 Next filing: 8/15/2024 SEC filing

Snapshot: Change Analysis

Compared to Q4 2023
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
NAMS 153,656 113.4%
ALPINE IMMUNE SCIENCES, INC. 64,436 108.0%
ARQT 58,754 207.6%
KRYS 53,249 43.4%
ORIC 37,250 189.0%
CGON 33,803 NEW
EWTX 31,078 106.5%
TARS 28,780 79.5%
PEPG 22,091 NEW
SLNO 18,765 100.3%
Top Reduces (Value $000, Stocks/ETFs)
MIRM -28,580 -14.9%
ANTX -23,944 -84.1%
MDGL -16,059 -100.0%
DYN -15,758 -100.0%
ACAD -14,188 -62.0%
CRNX -14,142 -100.0%
RYTM -14,109 -12.9%
VRNA -11,424 -19.1%
APGE -11,176 -100.0%
89bio, Inc. -10,700 -47.9%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type