4525EP200
Detailed investor-level table based on 13F positions.
Methodology:
Market value and % of portfolio use SEC reported VALUE ($000).
For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received.
Details.
Rows: 0
| Investor | History | Status | Shares held | Market value ($000) | % of portfolio | Previous % | Rank | Change in shares | % change in shares | Source | Date reported |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Aberdeen Group plc | History | New | 824,393 | 12,670 | 0.02% | — | 1 | +824,393 | New | Q2 2026 | Jul 31, 2026 |
| BVF INC/IL | History | New | 765,295 | 11,762 | 0.3% | — | 2 | +765,295 | New | Q2 2026 | Aug 14, 2026 |
| MILLENNIUM MANAGEMENT LLC | History | New | 740,347 | 11,379 | 0.0% | — | 3 | +740,347 | New | Q2 2026 | Aug 14, 2026 |
| Avidity Partners Management LP | History | New | 669,941 | 10,296 | 1.65% | — | 4 | +669,941 | New | Q2 2026 | Aug 14, 2026 |
| BRAIDWELL LP | History | New | 645,010 | 9,913 | 0.37% | — | 5 | +645,010 | New | Q2 2026 | Aug 14, 2026 |
| Laurion Capital Management LP | History | New | 610,326 | 9,380 | 0.24% | — | 6 | +610,326 | New | Q2 2026 | Aug 13, 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC | History | New | 571,561 | 8,784 | 0.0% | — | 7 | +571,561 | New | Q2 2026 | Aug 13, 2026 |
| Jones Hill Capital LP | History | New | 539,814 | 8,296 | 1.76% | — | 8 | +539,814 | New | Q2 2026 | Aug 13, 2026 |
| Woodline Partners LP | History | New | 471,528 | 7,247 | 0.02% | — | 9 | +471,528 | New | Q2 2026 | Aug 14, 2026 |
| Soleus Capital Management, L.P. | History | New | 450,000 | 6,916 | 0.24% | — | 10 | +450,000 | New | Q2 2026 | Aug 11, 2026 |
| Propel Bio Management, LLC | History | New | 325,022 | 4,995 | 2.61% | — | 11 | +325,022 | New | Q2 2026 | Aug 13, 2026 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | History | New | 259,690 | 3,991 | 0.0% | — | 12 | +259,690 | New | Q2 2026 | Aug 14, 2026 |
| Nantahala Capital Management, LLC | History | New | 250,646 | 3,852 | 0.13% | — | 13 | +250,646 | New | Q2 2026 | Aug 14, 2026 |
| UBS Group AG | History | New | 175,756 | 2,701 | 0.0% | — | 14 | +175,756 | New | Q2 2026 | Aug 13, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | History | New | 170,675 | 2,624 | 0.0% | — | 15 | +170,675 | New | Q2 2026 | Aug 12, 2026 |
| 683 Capital Management, LLC | History | New | 147,245 | 2,263 | 0.11% | — | 16 | +147,245 | New | Q2 2026 | Aug 14, 2026 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | History | New | 139,860 | 2,149 | 0.0% | — | 17 | +139,860 | New | Q2 2026 | Aug 14, 2026 |
| BlackRock, Inc. | History | New | 132,791 | 2,040 | 0.0% | — | 18 | +132,791 | New | Q2 2026 | Aug 07, 2026 |
| JANE STREET GROUP, LLC | History | New | 104,987 | 1,613 | 0.0% | — | 19 | +104,987 | New | Q2 2026 | Aug 14, 2026 |
| MARSHALL WACE, LLP | History | Reduced | 104,816 | 1,611 | 0.0% | 0.0% | 20 | -848,150 | -89.0% | Q2 2026 | Aug 13, 2026 |
| Jefferies Financial Group Inc. | History | New | 84,900 | 1,304 | 0.01% | — | 21 | +84,900 | New | Q2 2026 | Aug 17, 2026 |
| VANGUARD FIDUCIARY TRUST CO | History | New | 82,029 | 1,260 | 0.0% | — | 22 | +82,029 | New | Q2 2026 | Aug 13, 2026 |
| Ikarian Capital, LLC | History | New | 67,464 | 1,036 | 0.11% | — | 23 | +67,464 | New | Q2 2026 | Aug 14, 2026 |
| STATE STREET CORP | History | New | 61,259 | 941 | 0.0% | — | 24 | +61,259 | New | Q2 2026 | Sep 22, 2026 |
| Quadrature Capital Ltd | History | New | 37,786 | 580 | 0.0% | — | 25 | +37,786 | New | Q2 2026 | Aug 06, 2026 |
| CITADEL ADVISORS LLC | History | New | 35,380 | 543 | 0.0% | — | 26 | +35,380 | New | Q2 2026 | Sep 02, 2026 |
| Simplify Asset Management Inc. | History | New | 30,725 | 472 | 0.01% | — | 28 | +30,725 | New | Q2 2026 | Jul 16, 2026 |
| NORTHERN TRUST CORP | History | New | 30,720 | 472 | 0.0% | — | 27 | +30,720 | New | Q2 2026 | Aug 13, 2026 |
| MORGAN STANLEY | History | New | 23,748 | 365 | 0.0% | — | 29 | +23,748 | New | Q2 2026 | Aug 13, 2026 |
| Brevan Howard Capital Management LP | History | New | 23,181 | 356 | 0.0% | — | 30 | +23,181 | New | Q2 2026 | Aug 14, 2026 |
| BNP PARIBAS FINANCIAL MARKETS | History | New | 22,909 | 352 | 0.0% | — | 31 | +22,909 | New | Q2 2026 | Aug 13, 2026 |
| LPL Financial LLC | History | New | 17,441 | 268 | 0.0% | — | 32 | +17,441 | New | Q2 2026 | Aug 07, 2026 |
| MML INVESTORS SERVICES, LLC | History | New | 14,662 | 225 | 0.0% | — | 33 | +14,662 | New | Q2 2026 | Aug 07, 2026 |
| ALPS ADVISORS INC | History | New | 13,824 | 212 | 0.0% | — | 34 | +13,824 | New | Q2 2026 | Jul 29, 2026 |
| BOOTHBAY FUND MANAGEMENT, LLC | History | New | 13,057 | 200 | 0.0% | — | 35 | +13,057 | New | Q2 2026 | Aug 14, 2026 |
| Point72 Asset Management, L.P. | History | New | 10,806 | 166 | 0.0% | — | 36 | +10,806 | New | Q2 2026 | Aug 14, 2026 |
| Strategies Wealth Advisors, LLC | History | New | 10,000 | 153 | 0.01% | — | 37 | +10,000 | New | Q2 2026 | Aug 14, 2026 |
| China Universal Asset Management Co., Ltd. | History | New | 6,400 | 98 | 0.01% | — | 38 | +6,400 | New | Q2 2026 | Jul 24, 2026 |
| CITIGROUP INC | History | New | 4,569 | 70 | 0.0% | — | 39 | +4,569 | New | Q2 2026 | Aug 03, 2026 |
| Vanguard Global Advisers, LLC | History | New | 3,186 | 48 | 0.0% | — | 40 | +3,186 | New | Q2 2026 | Aug 13, 2026 |
| Belvedere Trading LLC | History | New | 20,900 | 32 | 0.0% | — | 41 | +20,900 | New | Q2 2026 | Jul 31, 2026 |
| ROYAL BANK OF CANADA | History | New | 1,000 | 15 | 0.0% | — | 42 | +1,000 | New | Q2 2026 | Aug 14, 2026 |
| OSAIC HOLDINGS, INC. | History | New | 1,000 | 15 | 0.0% | — | 43 | +1,000 | New | Q2 2026 | Aug 14, 2026 |
| Providence Capital Advisors, LLC | History | New | 682 | 10 | 0.0% | — | 44 | +682 | New | Q2 2026 | Aug 11, 2026 |
| BARCLAYS PLC | History | New | 494 | 7 | 0.0% | — | 45 | +494 | New | Q2 2026 | Aug 14, 2026 |
| SBI Securities Co., Ltd. | History | New | 373 | 5 | 0.0% | — | 46 | +373 | New | Q2 2026 | Jul 22, 2026 |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | History | New | 150 | 2 | 0.0% | — | 48 | +150 | New | Q2 2026 | Aug 12, 2026 |
| GROUP ONE TRADING LLC | History | New | 145 | 2 | 0.0% | — | 47 | +145 | New | Q2 2026 | Aug 13, 2026 |
| FMR LLC | History | New | 128 | 1 | 0.0% | — | 50 | +128 | New | Q2 2026 | Aug 13, 2026 |
| Rockefeller Capital Management L.P. | History | New | 100 | 1 | 0.0% | — | 52 | +100 | New | Q2 2026 | Aug 13, 2026 |
| WELLS FARGO & COMPANY/MN | History | New | 87 | 1 | 0.0% | — | 49 | +87 | New | Q2 2026 | Aug 14, 2026 |
| Allworth Financial LP | History | New | 84 | 1 | 0.0% | — | 51 | +84 | New | Q2 2026 | Aug 11, 2026 |
| JPMORGAN CHASE & CO | History | New | 38 | 0 | — | — | — | +38 | New | Q2 2026 | Aug 12, 2026 |
| SHP Wealth Management | History | New | 14 | 0 | — | — | — | +14 | New | Q2 2026 | Aug 11, 2026 |
| CALDWELL SUTTER CAPITAL, INC. | History | Added to | 10 | 0 | — | — | — | +7 | 233.33% | Q2 2026 | Aug 05, 2026 |
| DANSKE BANK A/S | History | New | 2 | 0 | — | — | — | +2 | New | Q2 2026 | Aug 10, 2026 |
| Caitong International Asset Management Co., Ltd | History | New | 2 | 0 | — | — | — | +2 | New | Q2 2026 | Aug 04, 2026 |
| Parallel Advisors, LLC | History | Closed out | 0 | 0 | — | — | — | -2 | -100.0% | Q2 2026 | Aug 05, 2026 |