81221K108
Detailed investor-level table based on 13F positions.
Methodology:
Market value and % of portfolio use SEC reported VALUE ($000).
For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received.
Details.
Rows: 0
| Investor | History | Status | Shares held | Market value ($000) | % of portfolio | Previous % | Rank | Change in shares | % change in shares | Source | Date reported |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ARCH Venture Management, LLC | History | No change | 6,294,951 | 136,600 | 12.42% | 12.42% | 1 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| GENERAL ATLANTIC, L.P. | History | No change | 6,101,582 | 132,526 | 4.56% | 4.56% | 2 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Sofinnova Investments, Inc. | History | No change | 3,564,871 | 77,428 | 4.0% | 4.0% | 3 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| GOLDMAN SACHS GROUP INC | History | No change | 2,178,642 | 47,320 | 0.0% | 0.0% | 4 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| TRV GP VI, LLC | History | No change | 2,061,222 | 44,769 | 19.27% | 19.27% | 5 | 0 | 0.0% | Q2 2026 | Aug 07, 2026 |
| CANADA PENSION PLAN INVESTMENT BOARD | History | No change | 1,975,791 | 42,914 | 0.02% | 0.02% | 6 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Foresite Capital Management VI LLC | History | No change | 1,779,521 | 38,651 | 6.02% | 6.02% | 7 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| FMR LLC | History | Added to | 1,837,672 | 37,065 | 0.0% | 0.0% | 8 | +652,572 | 55.06% | Q3 2026 | Nov 10, 2026 |
| JPMORGAN CHASE & CO | History | Reduced | 1,596,602 | 29,840 | 0.0% | 0.0% | 9 | -219,243 | -12.07% | Q3 2026 | Nov 12, 2026 |
| PRICE T ROWE ASSOCIATES INC /MD/ | History | No change | 1,308,604 | 28,424 | 0.0% | 0.0% | 10 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Bellevue Group AG | History | No change | 1,100,000 | 23,892 | 0.5% | 0.5% | 11 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| JENNISON ASSOCIATES LLC | History | No change | 1,079,669 | 23,450 | 0.01% | 0.01% | 12 | 0 | 0.0% | Q2 2026 | Aug 03, 2026 |
| Siren, L.L.C. | History | No change | 1,095,316 | 22,092 | 0.52% | 0.48% | 13 | 0 | 0.0% | Q3 2026 | Nov 12, 2026 |
| RA CAPITAL MANAGEMENT, L.P. | History | No change | 700,000 | 15,204 | 0.13% | 0.13% | 14 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC | History | No change | 599,217 | 13,014 | 0.0% | 0.0% | 15 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| Woodline Partners LP | History | No change | 586,345 | 12,735 | 0.04% | 0.04% | 16 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| PERCEPTIVE ADVISORS LLC | History | No change | 500,000 | 10,860 | 0.16% | 0.16% | 17 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| BRAIDWELL LP | History | No change | 500,000 | 10,860 | 0.4% | 0.4% | 18 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| PRINCIPAL FINANCIAL GROUP INC | History | Reduced | 377,391 | 7,611 | 0.0% | 0.0% | 19 | -37,281 | -8.99% | Q3 2026 | Nov 02, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | History | Added to | 377,231 | 7,610 | 0.0% | 0.0% | 20 | +201,365 | 114.5% | Q3 2026 | Nov 06, 2026 |
| Aberdeen Group plc | History | Reduced | 298,537 | 6,021 | 0.01% | 0.01% | 21 | -11,818 | -3.81% | Q3 2026 | Nov 10, 2026 |
| STATE STREET CORP | History | Added to | 250,798 | 5,058 | 0.0% | 0.0% | 22 | +184,148 | 276.29% | Q3 2026 | Nov 12, 2026 |
| BlackRock, Inc. | History | No change | 229,863 | 4,992 | 0.0% | 0.0% | 23 | 0 | 0.0% | Q2 2026 | Aug 07, 2026 |
| SEVEN GRAND MANAGERS, LLC | History | No change | 225,000 | 4,887 | 0.2% | 0.2% | 24 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| CITADEL ADVISORS LLC | History | No change | 191,144 | 4,151 | 0.0% | 0.0% | 25 | 0 | 0.0% | Q2 2026 | Sep 02, 2026 |
| Pier Capital, LLC | History | No change | 169,985 | 3,692 | 0.49% | 0.49% | 26 | 0 | 0.0% | Q2 2026 | Aug 05, 2026 |
| AMERIPRISE FINANCIAL INC | History | No change | 131,788 | 2,862 | 0.0% | 0.0% | 27 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | History | No change | 97,693 | 2,121 | 0.0% | 0.0% | 28 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| VANGUARD FIDUCIARY TRUST CO | History | No change | 87,772 | 1,906 | 0.0% | 0.0% | 29 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| AdvisorShares Investments LLC | History | New | 94,000 | 1,895 | 0.24% | — | 30 | +94,000 | New | Q3 2026 | Nov 09, 2026 |
| Pentwater Capital Management LP | History | No change | 83,000 | 1,802 | 0.01% | 0.01% | 31 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | History | No change | 82,565 | 1,793 | 0.0% | 0.0% | 32 | 0 | 0.0% | Q2 2026 | Sep 09, 2026 |
| Alyeska Investment Group, L.P. | History | No change | 75,000 | 1,629 | 0.0% | 0.0% | 33 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| ALPS ADVISORS INC | History | Added to | 70,921 | 1,430 | 0.01% | 0.01% | 34 | +16,593 | 30.54% | Q3 2026 | Nov 02, 2026 |
| TD ASSET MANAGEMENT INC | History | No change | 47,944 | 1,041 | 0.0% | 0.0% | 35 | 0 | 0.0% | Q2 2026 | Aug 04, 2026 |
| MILLENNIUM MANAGEMENT LLC | History | No change | 45,337 | 984 | 0.0% | 0.0% | 36 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| GSA CAPITAL PARTNERS LLP | History | No change | 33,178 | 721 | 0.05% | 0.05% | 37 | 0 | 0.0% | Q2 2026 | Aug 06, 2026 |
| DAFNA Capital Management LLC | History | No change | 32,400 | 703 | 0.13% | 0.13% | 38 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| NORTHERN TRUST CORP | History | No change | 31,802 | 690 | 0.0% | 0.0% | 39 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| Bank of New York Mellon Corp | History | New | 29,489 | 594 | 0.0% | — | 40 | +29,489 | New | Q3 2026 | Nov 05, 2026 |
| ADAR1 Capital Management, LLC | History | No change | 26,000 | 564 | 0.03% | 0.03% | 41 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Ghisallo Capital Management LLC | History | No change | 25,000 | 543 | 0.01% | 0.01% | 42 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Burkehill Global Management, LP | History | No change | 25,000 | 543 | 0.02% | 0.02% | 43 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Nuveen, LLC | History | New | 18,603 | 375 | 0.0% | — | 44 | +18,603 | New | Q3 2026 | Nov 10, 2026 |
| HighTower Advisors, LLC | History | No change | 16,666 | 336 | 0.0% | 0.0% | 45 | 0 | 0.0% | Q3 2026 | Nov 09, 2026 |
| Invesco Ltd. | History | New | 14,107 | 284 | 0.0% | — | 46 | +14,107 | New | Q3 2026 | Nov 12, 2026 |
| MORGAN STANLEY | History | No change | 11,692 | 253 | 0.0% | 0.0% | 47 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| UBS Group AG | History | Reduced | 12,463 | 251 | 0.0% | 0.0% | 48 | -266,721 | -95.54% | Q3 2026 | Nov 10, 2026 |
| DEUTSCHE BANK AG\ | History | New | 12,024 | 242 | 0.0% | — | 49 | +12,024 | New | Q3 2026 | Nov 06, 2026 |
| XTX Topco Ltd | History | No change | 10,983 | 238 | 0.0% | 0.0% | 50 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| RHUMBLINE ADVISERS | History | New | 11,677 | 235 | 0.0% | — | 51 | +11,677 | New | Q3 2026 | Nov 10, 2026 |
| Weiss Asset Management LP | History | No change | 10,000 | 217 | 0.0% | 0.0% | 52 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Zimmer Partners, LP | History | No change | 10,000 | 217 | 0.0% | 0.0% | 53 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | History | No change | 9,081 | 197 | 0.0% | 0.0% | 54 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| Vanguard Global Advisers, LLC | History | No change | 7,159 | 155 | 0.0% | 0.0% | 55 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| CITIGROUP INC | History | Added to | 6,820 | 137 | 0.0% | 0.0% | 56 | +4,366 | 177.91% | Q3 2026 | Nov 04, 2026 |
| BARCLAYS PLC | History | Added to | 5,600 | 112 | 0.0% | 0.0% | 57 | +4,763 | 569.06% | Q3 2026 | Nov 06, 2026 |
| STRS OHIO | History | New | 3,800 | 76 | 0.0% | — | 58 | +3,800 | New | Q3 2026 | Oct 30, 2026 |
| Police & Firemen's Retirement System of New Jersey | History | New | 3,342 | 67 | 0.0% | — | 59 | +3,342 | New | Q3 2026 | Nov 09, 2026 |
| BNP PARIBAS FINANCIAL MARKETS | History | New | 3,300 | 66 | 0.0% | — | 60 | +3,300 | New | Q3 2026 | Nov 12, 2026 |
| JONES FINANCIAL COMPANIES LLLP | History | No change | 2,256 | 48 | 0.0% | 0.0% | 61 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| ASSETMARK, INC | History | Added to | 1,767 | 35 | 0.0% | 0.0% | 62 | +336 | 23.48% | Q3 2026 | Oct 21, 2026 |
| Russell Investments Group, Ltd. | History | New | 1,093 | 22 | 0.0% | — | 63 | +1,093 | New | Q3 2026 | Nov 06, 2026 |
| Sterling Capital Management LLC | History | New | 391 | 7 | 0.0% | — | 64 | +391 | New | Q3 2026 | Oct 22, 2026 |
| Farther Finance Advisors, LLC | History | New | 334 | 6 | 0.0% | — | 65 | +334 | New | Q3 2026 | Oct 08, 2026 |
| Global Retirement Partners, LLC | History | New | 171 | 3 | 0.0% | — | 66 | +171 | New | Q3 2026 | Nov 10, 2026 |
| OSAIC HOLDINGS, INC. | History | New | 100 | 2 | 0.0% | — | 67 | +100 | New | Q3 2026 | Nov 12, 2026 |
| Squarepoint Ops LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -24,753 | -100.0% | Q3 2026 | Nov 09, 2026 |