BICYCLE THERAPEUTICS PLC - BCYC
Detailed investor-level table based on 13F positions.
Methodology:
Market value and % of portfolio use SEC reported VALUE ($000).
For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received.
Details.
Rows: 0
| Investor | History | Status | Shares held | Market value ($000) | % of portfolio | Previous % | Rank | Change in shares | % change in shares | Source | Date reported |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP | History | No change | 10,885,357 | 46,153 | 0.23% | 0.23% | 1 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| FCPM III SERVICES B.V. | History | No change | 3,468,430 | 14,706 | 1.96% | 1.96% | 2 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| ARMISTICE CAPITAL, LLC | History | No change | 3,398,000 | 14,407 | 0.18% | 0.18% | 3 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Long Focus Capital Management, LLC | History | No change | 3,310,687 | 14,037 | 0.36% | 0.36% | 4 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| ACADIAN ASSET MANAGEMENT LLC | History | No change | 1,968,025 | 8,319 | 0.01% | 0.01% | 5 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| RENAISSANCE TECHNOLOGIES LLC | History | No change | 1,533,400 | 6,501 | 0.01% | 0.01% | 6 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| GSK plc | History | No change | 1,529,561 | 6,485 | 1.08% | 1.08% | 7 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| PRICE T ROWE ASSOCIATES INC /MD/ | History | No change | 902,150 | 3,826 | 0.0% | 0.0% | 8 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| MARSHALL WACE, LLP | History | No change | 797,940 | 3,383 | 0.0% | 0.0% | 9 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| Qube Research & Technologies Ltd | History | No change | 775,567 | 3,288 | 0.0% | 0.0% | 10 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| MORGAN STANLEY | History | No change | 667,269 | 2,829 | 0.0% | 0.0% | 11 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| CITADEL ADVISORS LLC | History | No change | 627,725 | 2,661 | 0.0% | 0.0% | 12 | 0 | 0.0% | Q2 2026 | Sep 02, 2026 |
| SCHRODER INVESTMENT MANAGEMENT GROUP | History | No change | 615,833 | 2,555 | 0.0% | 0.0% | 13 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| MILLENNIUM MANAGEMENT LLC | History | No change | 553,967 | 2,348 | 0.0% | 0.0% | 14 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| DIADEMA PARTNERS LP | History | No change | 462,724 | 1,961 | 0.25% | 0.25% | 15 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| JANE STREET GROUP, LLC | History | No change | 454,763 | 1,928 | 0.0% | 0.0% | 16 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Peapod Lane Capital LLC | History | Reduced | 501,708 | 1,846 | 1.38% | 1.54% | 17 | -36,270 | -6.74% | Q3 2026 | Oct 22, 2026 |
| TWO SIGMA INVESTMENTS, LP | History | No change | 434,577 | 1,842 | 0.0% | 0.0% | 18 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | History | No change | 352,357 | 1,493 | 0.0% | 0.0% | 19 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Birchview Capital, LP | History | No change | 313,616 | 1,329 | 0.62% | 0.62% | 20 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| BlackRock, Inc. | History | No change | 280,386 | 1,188 | 0.0% | 0.0% | 21 | 0 | 0.0% | Q2 2026 | Aug 07, 2026 |
| MOORE CAPITAL MANAGEMENT, LP | History | No change | 275,000 | 1,166 | 0.02% | 0.02% | 22 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Rangeley Capital, LLC | History | No change | 253,500 | 1,074 | 0.98% | 0.98% | 23 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| FLAX POND CAPITAL, LLC | History | No change | 196,136 | 910 | 0.72% | 0.72% | 24 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| Palo Alto Investors LP | History | No change | 201,890 | 856 | 0.12% | 0.12% | 25 | 0 | 0.0% | Q2 2026 | Aug 19, 2026 |
| Sculptor Capital LP | History | No change | 197,904 | 839 | 0.01% | 0.01% | 26 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Eversept Partners, LP | History | No change | 190,715 | 808 | 0.04% | 0.04% | 27 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Jump Financial, LLC | History | No change | 167,100 | 708 | 0.01% | 0.01% | 28 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| Point72 Asset Management, L.P. | History | No change | 149,936 | 635 | 0.0% | 0.0% | 29 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| PINNACLE ASSOCIATES LTD | History | Reduced | 160,551 | 590 | 0.01% | 0.01% | 30 | -29,439 | -15.5% | Q3 2026 | Oct 20, 2026 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | History | No change | 127,863 | 542 | 0.0% | 0.0% | 31 | 0 | 0.0% | Q2 2026 | Sep 09, 2026 |
| GOLDMAN SACHS GROUP INC | History | No change | 121,281 | 514 | 0.0% | 0.0% | 32 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Persistent Asset Partners Ltd | History | No change | 117,254 | 497 | 0.15% | 0.15% | 33 | 0 | 0.0% | Q2 2026 | Aug 06, 2026 |
| XTX Topco Ltd | History | No change | 109,801 | 465 | 0.01% | 0.01% | 34 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Quadrature Capital Ltd | History | No change | 104,092 | 441 | 0.0% | 0.0% | 35 | 0 | 0.0% | Q2 2026 | Aug 06, 2026 |
| TD ASSET MANAGEMENT INC | History | No change | 91,992 | 390 | 0.0% | 0.0% | 36 | 0 | 0.0% | Q2 2026 | Aug 04, 2026 |
| Virtus Investment Advisers, LLC | History | No change | 80,789 | 342 | 0.08% | 0.08% | 37 | 0 | 0.0% | Q2 2026 | Aug 11, 2026 |
| NANO CAP NEW MILLENNIUM GROWTH FUND L P | History | No change | 80,000 | 339 | 0.26% | 0.26% | 38 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| EntryPoint Capital, LLC | History | No change | 77,743 | 329 | 0.08% | 0.08% | 39 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| HRT FINANCIAL LP | History | No change | 66,237 | 280 | 0.0% | 0.0% | 40 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| DAFNA Capital Management LLC | History | No change | 64,492 | 273 | 0.05% | 0.05% | 41 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| State of Tennessee, Department of Treasury | History | No change | 61,153 | 259 | 0.0% | 0.0% | 42 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| ALPS ADVISORS INC | History | Added to | 66,501 | 244 | 0.0% | 0.0% | 43 | +15,379 | 30.08% | Q3 2026 | Nov 02, 2026 |
| SEI INVESTMENTS CO | History | No change | 52,784 | 223 | 0.0% | 0.0% | 44 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Verdad Advisers, LP | History | No change | 51,100 | 216 | 0.21% | 0.21% | 45 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| ADAR1 Capital Management, LLC | History | No change | 50,638 | 214 | 0.01% | 0.01% | 46 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| SIMPLEX TRADING, LLC | History | Added to | 46,923 | 172 | 0.0% | 0.0% | 47 | +11,691 | 33.18% | Q3 2026 | Nov 04, 2026 |
| GSA CAPITAL PARTNERS LLP | History | No change | 30,785 | 131 | 0.01% | 0.01% | 48 | 0 | 0.0% | Q2 2026 | Aug 06, 2026 |
| Trexquant Investment LP | History | No change | 31,044 | 131 | 0.0% | 0.0% | 49 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| STATE STREET CORP | History | No change | 30,829 | 130 | 0.0% | 0.0% | 50 | 0 | 0.0% | Q2 2026 | Sep 22, 2026 |
| AXQ CAPITAL, LP | History | No change | 27,368 | 116 | 0.01% | 0.01% | 51 | 0 | 0.0% | Q2 2026 | Aug 06, 2026 |
| WOODSTOCK CORP | History | No change | 29,146 | 107 | 0.01% | 0.01% | 52 | 0 | 0.0% | Q3 2026 | Oct 13, 2026 |
| D. E. Shaw & Co., Inc. | History | No change | 25,457 | 107 | 0.0% | 0.0% | 53 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Invesco Ltd. | History | No change | 24,802 | 105 | 0.0% | 0.0% | 54 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| National Philanthropic Trust | History | No change | 24,723 | 104 | 0.0% | 0.0% | 55 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Forefront Analytics, LLC | History | No change | 21,822 | 92 | 0.1% | 0.1% | 56 | 0 | 0.0% | Q2 2026 | Aug 12, 2026 |
| Walleye Capital LLC | History | No change | 20,900 | 88 | 0.0% | 0.0% | 57 | 0 | 0.0% | Q2 2026 | Aug 03, 2026 |
| STIFEL FINANCIAL CORP | History | No change | 20,479 | 86 | 0.0% | 0.0% | 58 | 0 | 0.0% | Q2 2026 | Aug 12, 2026 |
| Vontobel Holding Ltd. | History | Added to | 23,000 | 84 | 0.0% | 0.0% | 59 | +3,000 | 15.0% | Q3 2026 | Oct 16, 2026 |
| AIGEN INVESTMENT MANAGEMENT, LP | History | No change | 19,319 | 81 | 0.02% | 0.02% | 60 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | History | No change | 19,035 | 80 | 0.0% | 0.0% | 61 | 0 | 0.0% | Q2 2026 | Aug 12, 2026 |
| Pinnacle Wealth Management Advisory Group, LLC | History | Added to | 20,985 | 77 | 0.0% | 0.0% | 62 | +10,000 | 91.03% | Q3 2026 | Oct 23, 2026 |
| State of New Jersey Common Pension Fund D | History | No change | 20,105 | 73 | 0.0% | 0.0% | 63 | 0 | 0.0% | Q3 2026 | Nov 05, 2026 |
| RHUMBLINE ADVISERS | History | No change | 15,967 | 67 | 0.0% | 0.0% | 64 | 0 | 0.0% | Q2 2026 | Aug 11, 2026 |
| UBS Group AG | History | No change | 15,459 | 65 | 0.0% | 0.0% | 65 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| PORTLAND INVESTMENT COUNSEL INC. | History | No change | 15,000 | 63 | 0.02% | 0.02% | 66 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| Federation des caisses Desjardins du Quebec | History | No change | 14,302 | 60 | 0.0% | 0.0% | 67 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| Erste Asset Management GmbH | History | No change | 14,000 | 58 | 0.0% | 0.0% | 68 | 0 | 0.0% | Q2 2026 | Jul 28, 2026 |
| Cerity Partners LLC | History | No change | 13,570 | 57 | 0.0% | 0.0% | 69 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Schonfeld Strategic Advisors LLC | History | No change | 13,399 | 56 | 0.0% | 0.0% | 70 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| JPMORGAN CHASE & CO | History | No change | 13,056 | 54 | 0.0% | 0.0% | 71 | 0 | 0.0% | Q2 2026 | Aug 12, 2026 |
| HORIZON KINETICS ASSET MANAGEMENT LLC | History | No change | 12,584 | 53 | 0.0% | 0.0% | 72 | 0 | 0.0% | Q2 2026 | Aug 11, 2026 |
| Aquatic Capital Management LLC | History | No change | 12,343 | 52 | 0.0% | 0.0% | 73 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Jain Global LLC | History | No change | 12,000 | 50 | 0.0% | 0.0% | 74 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Crossmark Global Holdings, Inc. | History | Reduced | 11,214 | 41 | 0.0% | 0.0% | 75 | -188 | -1.65% | Q3 2026 | Oct 21, 2026 |
| COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS | History | No change | 10,116 | 37 | 0.0% | 0.0% | 76 | 0 | 0.0% | Q3 2026 | Nov 03, 2026 |
| China Universal Asset Management Co., Ltd. | History | Added to | 8,523 | 31 | 0.0% | 0.0% | 77 | +1,103 | 14.87% | Q3 2026 | Oct 27, 2026 |
| GAMMA Investing LLC | History | Reduced | 7,561 | 27 | 0.0% | 0.0% | 78 | -143 | -1.86% | Q3 2026 | Oct 08, 2026 |
| State of Wyoming | History | Reduced | 7,129 | 26 | 0.0% | 0.0% | 79 | -3,631 | -33.75% | Q3 2026 | Oct 28, 2026 |
| NATIXIS | History | No change | 4,645 | 19 | 0.0% | 0.0% | 80 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| Tower Research Capital LLC (TRC) | History | No change | 3,669 | 15 | 0.0% | 0.0% | 81 | 0 | 0.0% | Q2 2026 | Aug 11, 2026 |
| BARCLAYS PLC | History | No change | 3,149 | 13 | 0.0% | 0.0% | 82 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| ROYAL BANK OF CANADA | History | No change | 2,500 | 11 | 0.0% | 0.0% | 83 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Mirae Asset Global Investments Co., Ltd. | History | Added to | 2,387 | 8 | 0.0% | 0.0% | 85 | +302 | 14.48% | Q3 2026 | Oct 28, 2026 |
| GROUP ONE TRADING LLC | History | No change | 1,938 | 8 | 0.0% | 0.0% | 84 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| CITIGROUP INC | History | Added to | 1,241 | 4 | 0.0% | 0.0% | 86 | +66 | 5.62% | Q3 2026 | Nov 04, 2026 |
| BNP PARIBAS FINANCIAL MARKETS | History | No change | 1,016 | 4 | 0.0% | 0.0% | 87 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| GF FUND MANAGEMENT CO. LTD. | History | Added to | 1,046 | 3 | 0.0% | 0.0% | 88 | +84 | 8.73% | Q3 2026 | Oct 26, 2026 |
| JONES FINANCIAL COMPANIES LLLP | History | No change | 700 | 2 | 0.0% | 0.0% | 89 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Quarry LP | History | No change | 537 | 2 | 0.0% | 0.0% | 90 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Arax Advisory Partners | History | No change | 304 | 1 | 0.0% | 0.0% | 91 | 0 | 0.0% | Q2 2026 | Aug 10, 2026 |
| HighMark Wealth Management LLC | History | No change | 435 | 1 | 0.0% | 0.0% | 92 | 0 | 0.0% | Q2 2026 | Aug 12, 2026 |
| Marquette Asset Management, LLC | History | Closed out | 0 | 0 | — | 0.04% | — | -72,854 | -100.0% | Q3 2026 | Oct 09, 2026 |
| FNY Investment Advisers, LLC | History | Closed out | 0 | 0 | — | 0.04% | — | -26,250 | -100.0% | Q3 2026 | Oct 16, 2026 |
| ASSETMARK, INC | History | Closed out | 0 | 0 | — | 0.0% | — | -1,588 | -100.0% | Q3 2026 | Oct 21, 2026 |
| Caitong International Asset Management Co., Ltd | History | Added to | 126 | 0 | — | — | — | +9 | 7.69% | Q3 2026 | Oct 29, 2026 |
| WELLS FARGO & COMPANY/MN | History | No change | 200 | 0 | — | — | — | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A. | History | No change | 9 | 0 | — | — | — | 0 | 0.0% | Q3 2026 | Oct 22, 2026 |
| Winch Advisory Services, LLC | History | No change | 172 | 0 | — | — | — | 0 | 0.0% | Q2 2026 | Aug 06, 2026 |
| OSAIC HOLDINGS, INC. | History | No change | 10 | 0 | — | — | — | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| EverSource Wealth Advisors, LLC | History | No change | 147 | 0 | — | — | — | 0 | 0.0% | Q3 2026 | Nov 04, 2026 |
| SBI Securities Co., Ltd. | History | No change | 6 | 0 | — | — | — | 0 | 0.0% | Q3 2026 | Oct 21, 2026 |
| Caitlin John, LLC | History | No change | 2 | 0 | — | — | — | 0 | 0.0% | Q2 2026 | Aug 17, 2026 |