CRESCENT BIOPHARMA, INC. - CBIO

Detailed investor-level table based on 13F positions.

Shareholders (13F)

Quarter: Q4 2025 · Compare: Q3 2025
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
FMR LLC History Added to 4,133,514 49,023 0.0% 0.0% 1 +2,718,834 192.19% Q4 2025 Feb 17, 2026
BVF INC/IL History Added to 2,748,763 32,600 1.1% 0.67% 2 +1,360,900 98.06% Q4 2025 Feb 17, 2026
Fairmount Funds Management LLC History Added to 2,747,866 32,589 2.48% 1.48% 3 +1,360,000 97.99% Q4 2025 Feb 17, 2026
VR Adviser, LLC History Added to 2,133,576 25,304 1.25% 0.93% 4 +745,712 53.73% Q4 2025 Feb 17, 2026
FCPM III SERVICES B.V. History New 1,677,852 19,899 2.61% 5 +1,677,852 New Q4 2025 Feb 17, 2026
Vestal Point Capital, LP History New 1,500,000 17,790 0.6% 6 +1,500,000 New Q4 2025 Feb 17, 2026
Opaleye Management Inc. History New 1,178,300 13,974 1.84% 7 +1,178,300 New Q4 2025 Feb 17, 2026
TANG CAPITAL MANAGEMENT LLC History Added to 872,398 10,346 0.51% 0.31% 8 +192,574 28.33% Q4 2025 Feb 17, 2026
ADAR1 Capital Management, LLC History New 606,000 7,187 0.53% 9 +606,000 New Q4 2025 Feb 18, 2026
Logos Global Management LP History No change 600,000 7,116 0.43% 0.64% 10 0 0.0% Q4 2025 Feb 17, 2026
VANGUARD GROUP INC History Reduced 557,506 6,612 0.0% 0.0% 11 -100,394 -15.26% Q4 2025 Jan 29, 2026
PERCEPTIVE ADVISORS LLC History No change 453,686 5,380 0.1% 0.16% 12 0 0.0% Q4 2025 Feb 17, 2026
Deep Track Capital, LP History No change 453,686 5,380 0.1% 0.15% 13 0 0.0% Q4 2025 Feb 13, 2026
Boxer Capital Management, LLC History No change 453,686 5,380 1.18% 1.72% 14 0 0.0% Q4 2025 Feb 17, 2026
RTW INVESTMENTS, LP History New 372,856 4,422 0.04% 15 +372,856 New Q4 2025 Feb 17, 2026
NEXTBio Capital Management LP History New 372,856 4,422 2.59% 16 +372,856 New Q4 2025 Feb 13, 2026
Remedium Capital Partners, LLC History New 361,250 4,284 2.52% 17 +361,250 New Q4 2025 Feb 12, 2026
PRICE T ROWE ASSOCIATES INC /MD/ History Reduced 338,125 4,011 0.0% 0.0% 18 -45,470 -11.85% Q4 2025 Feb 17, 2026
DRIEHAUS CAPITAL MANAGEMENT LLC History No change 302,457 3,587 0.02% 0.03% 19 0 0.0% Q4 2025 Feb 17, 2026
Point72 Asset Management, L.P. History New 300,000 3,558 0.0% 20 +300,000 New Q4 2025 Feb 17, 2026
HEIGHTS CAPITAL MANAGEMENT, INC History New 264,000 3,131 1.12% 21 +264,000 New Q4 2025 Feb 17, 2026
Alyeska Investment Group, L.P. History New 264,000 3,108 0.01% 22 +264,000 New Q4 2025 Feb 13, 2026
WELLINGTON MANAGEMENT GROUP LLP History Added to 143,412 1,626 0.0% 0.0% 23 +125,714 710.33% Q4 2025 Feb 17, 2026
TWO SIGMA INVESTMENTS, LP History Added to 125,224 1,485 0.0% 0.0% 24 +96,906 342.21% Q4 2025 Feb 17, 2026
BALYASNY ASSET MANAGEMENT L.P. History New 111,715 1,324 0.0% 25 +111,715 New Q4 2025 Feb 17, 2026
BlackRock, Inc. History Added to 109,230 1,295 0.0% 0.0% 26 +115 0.11% Q4 2025 Feb 12, 2026
GEODE CAPITAL MANAGEMENT, LLC History Added to 91,079 1,081 0.0% 0.0% 27 +21,945 31.74% Q4 2025 Feb 09, 2026
Stonepine Capital Management, LLC History New 87,682 1,039 0.76% 28 +87,682 New Q4 2025 Feb 13, 2026
Blackstone Inc. History No change 75,614 896 0.0% 0.0% 29 0 0.0% Q4 2025 Feb 17, 2026
Woodline Partners LP History New 74,000 877 0.0% 30 +74,000 New Q4 2025 Feb 17, 2026
Burkehill Global Management, LP History New 74,000 844 0.06% 31 +74,000 New Q4 2025 Feb 17, 2026
Jefferies Financial Group Inc. History Reduced 64,244 761 0.0% 0.01% 32 -38,470 -37.45% Q4 2025 Feb 09, 2026
MILLENNIUM MANAGEMENT LLC History New 61,882 733 0.0% 33 +61,882 New Q4 2025 Feb 17, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History New 57,048 676 0.0% 34 +57,048 New Q4 2025 Feb 17, 2026
RENAISSANCE TECHNOLOGIES LLC History Added to 46,700 553 0.0% 0.0% 35 +19,800 73.61% Q4 2025 Feb 12, 2026
TWO SIGMA ADVISERS, LP History New 32,500 385 0.0% 36 +32,500 New Q4 2025 Feb 17, 2026
MORGAN STANLEY History Added to 27,521 326 0.0% 0.0% 37 +27,376 18880.0% Q4 2025 Feb 13, 2026
STATE STREET CORP History Added to 26,217 310 0.0% 0.0% 38 +7,600 40.82% Q4 2025 Feb 13, 2026
GOLDMAN SACHS GROUP INC History Reduced 25,245 299 0.0% 0.0% 39 -11,730 -31.72% Q4 2025 Mar 25, 2026
MOORE CAPITAL MANAGEMENT, LP History New 25,000 296 0.0% 40 +25,000 New Q4 2025 Feb 17, 2026
MANUFACTURERS LIFE INSURANCE COMPANY, THE History New 24,903 288 0.0% 41 +24,903 New Q4 2025 Feb 13, 2026
JPMORGAN CHASE & CO History Added to 23,339 276 0.0% 42 +23,322 137188.24% Q4 2025 Feb 11, 2026
JANE STREET GROUP, LLC History New 22,965 272 0.0% 43 +22,965 New Q4 2025 Feb 12, 2026
MARSHALL WACE, LLP History Reduced 21,826 258 0.0% 0.0% 44 -21,868 -50.05% Q4 2025 Feb 13, 2026
NORTHERN TRUST CORP History Added to 17,229 204 0.0% 0.0% 45 +413 2.46% Q4 2025 Feb 17, 2026
Quadrature Capital Ltd History New 13,246 157 0.0% 46 +13,246 New Q4 2025 Feb 17, 2026
HRT FINANCIAL LP History New 13,083 155 0.0% 47 +13,083 New Q4 2025 Feb 12, 2026
OMERS ADMINISTRATION Corp History New 11,600 137 0.0% 48 +11,600 New Q4 2025 Feb 13, 2026
UBS Group AG History Reduced 7,125 84 0.0% 0.0% 49 -5,536 -43.72% Q4 2025 Jan 29, 2026
BANK OF AMERICA CORP /DE/ History Added to 5,573 66 0.0% 0.0% 50 +1,710 44.27% Q4 2025 Feb 17, 2026
BNP PARIBAS FINANCIAL MARKETS History Added to 3,585 42 0.0% 51 +3,581 89525.0% Q4 2025 Feb 10, 2026
CITIGROUP INC History Reduced 623 7 0.0% 0.0% 52 -175 -21.93% Q4 2025 Feb 13, 2026
Tower Research Capital LLC (TRC) History Added to 409 4 0.0% 0.0% 53 +209 104.5% Q4 2025 Feb 17, 2026
Commodore Capital LP History Closed out 0 0 0.26% -450,829 -100.0% Q3 2025 Nov 14, 2025
Frazier Life Sciences Management, L.P. History Closed out 0 0 0.1% -272,951 -100.0% Q3 2025 Nov 14, 2025
ADAGE CAPITAL PARTNERS GP, L.L.C. History Closed out 0 0 0.0% -200,005 -100.0% Q3 2025 Nov 14, 2025
Soleus Capital Management, L.P. History Closed out 0 0 0.12% -200,000 -100.0% Q3 2025 Nov 14, 2025
CITADEL ADVISORS LLC History Closed out 0 0 0.0% -25,593 -100.0% Q3 2025 Nov 14, 2025
Affinity Asset Advisors, LLC History Closed out 0 0 0.02% -17,998 -100.0% Q3 2025 Nov 13, 2025
GROUP ONE TRADING LLC History Reduced 4 0 -78 -95.12% Q4 2025 Feb 12, 2026
Avion Wealth History New 40 0 +40 New Q4 2025 Jan 23, 2026
ROYAL BANK OF CANADA History New 20 0 +20 New Q4 2025 Feb 17, 2026
OSAIC HOLDINGS, INC. History No change 26 0 0 0.0% Q4 2025 Feb 17, 2026
SBI Securities Co., Ltd. History No change 68 0 0 0.0% Q4 2025 Feb 03, 2026