C4 Therapeutics, Inc. - CCCC
Detailed investor-level table based on 13F positions.
Early Q1 2026 data: only 8 institutional holders reported so far. The full shareholder list will grow as more funds file with the SEC.
Methodology:
Market value and % of portfolio use SEC reported VALUE ($000).
For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received.
Details.
Rows: 0
| Investor | History | Status | Shares held | Market value ($000) | % of portfolio | Previous % | Rank | Change in shares | % change in shares | Source | Date reported |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Point72 Asset Management, L.P. | History | New | 9,439,328 | 18,029 | 0.02% | — | 1 | +9,439,328 | New | Q4 2025 | Feb 17, 2026 |
| MORGAN STANLEY | History | Added to | 8,981,662 | 17,154 | 0.0% | 0.0% | 2 | +4,009,630 | 80.64% | Q4 2025 | Feb 13, 2026 |
| RA CAPITAL MANAGEMENT, L.P. | History | New | 8,000,000 | 15,280 | 0.16% | — | 3 | +8,000,000 | New | Q4 2025 | Feb 17, 2026 |
| Bain Capital Life Sciences Investors, LLC | History | Added to | 7,171,910 | 13,698 | 1.05% | 0.16% | 4 | +6,060,000 | 545.01% | Q4 2025 | Feb 17, 2026 |
| Lynx1 Capital Management LP | History | No change | 7,098,133 | 13,557 | 2.74% | 3.21% | 5 | 0 | 0.0% | Q4 2025 | Feb 17, 2026 |
| VANGUARD GROUP INC | History | Added to | 4,379,815 | 8,365 | 0.0% | 0.0% | 6 | +1,188,258 | 37.23% | Q4 2025 | Jan 29, 2026 |
| WASATCH ADVISORS LP | History | New | 4,344,918 | 8,298 | 0.05% | — | 7 | +4,344,918 | New | Q4 2025 | Feb 12, 2026 |
| Soleus Capital Management, L.P. | History | Reduced | 3,803,942 | 7,265 | 0.27% | 0.79% | 8 | -3,250,000 | -46.07% | Q4 2025 | Feb 12, 2026 |
| BANK OF AMERICA CORP /DE/ | History | Added to | 2,387,586 | 4,560 | 0.0% | 0.0% | 9 | +334,424 | 16.29% | Q4 2025 | Feb 17, 2026 |
| SILVERARC CAPITAL MANAGEMENT, LLC | History | Added to | 1,994,224 | 3,808 | 0.53% | 0.57% | 10 | +96,841 | 5.1% | Q4 2025 | Feb 12, 2026 |
| BlackRock, Inc. | History | Added to | 1,969,814 | 3,762 | 0.0% | 0.0% | 11 | +374,175 | 23.45% | Q4 2025 | Feb 12, 2026 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | History | Added to | 1,881,183 | 3,593 | 0.0% | 0.0% | 12 | +1,173,246 | 165.73% | Q4 2025 | Feb 17, 2026 |
| RENAISSANCE TECHNOLOGIES LLC | History | Added to | 1,602,580 | 3,060 | 0.0% | 0.0% | 13 | +665,630 | 71.04% | Q4 2025 | Feb 12, 2026 |
| TWO SIGMA INVESTMENTS, LP | History | Added to | 1,509,603 | 2,883 | 0.0% | 0.0% | 14 | +674,877 | 80.85% | Q4 2025 | Feb 17, 2026 |
| ORBIMED ADVISORS LLC | History | Reduced | 1,404,902 | 2,683 | 0.05% | 0.27% | 15 | -3,830,244 | -73.16% | Q4 2025 | Feb 17, 2026 |
| MILLENNIUM MANAGEMENT LLC | History | Reduced | 1,188,969 | 2,270 | 0.0% | 0.0% | 16 | -835,256 | -41.26% | Q4 2025 | Feb 17, 2026 |
| GOLDMAN SACHS GROUP INC | History | Added to | 1,089,020 | 2,080 | 0.0% | 0.0% | 17 | +629,127 | 136.8% | Q4 2025 | Mar 25, 2026 |
| TWO SIGMA ADVISERS, LP | History | Added to | 1,068,200 | 2,040 | 0.0% | 0.0% | 18 | +305,100 | 39.98% | Q4 2025 | Feb 17, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | History | Added to | 988,878 | 1,889 | 0.0% | 0.0% | 19 | +263,574 | 36.34% | Q4 2025 | Feb 09, 2026 |
| JANE STREET GROUP, LLC | History | Added to | 874,794 | 1,670 | 0.0% | 0.0% | 20 | +671,226 | 329.73% | Q4 2025 | Feb 12, 2026 |
| WELLS FARGO & COMPANY/MN | History | Added to | 809,260 | 1,545 | 0.0% | 0.0% | 21 | +790,600 | 4236.87% | Q4 2025 | Feb 13, 2026 |
| ACADIAN ASSET MANAGEMENT LLC | History | Added to | 657,173 | 1,251 | 0.0% | 0.0% | 22 | +529,065 | 412.98% | Q4 2025 | Feb 10, 2026 |
| CITADEL ADVISORS LLC | History | Reduced | 498,608 | 952 | 0.0% | 0.0% | 23 | -37,241 | -6.95% | Q4 2025 | Feb 17, 2026 |
| Walleye Capital LLC | History | Added to | 468,541 | 894 | 0.0% | 0.0% | 24 | +444,041 | 1812.41% | Q4 2025 | Feb 13, 2026 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | History | Added to | 449,432 | 858 | 0.0% | 0.0% | 25 | +98,826 | 28.19% | Q4 2025 | Feb 13, 2026 |
| 683 Capital Management, LLC | History | New | 400,000 | 764 | 0.03% | — | 26 | +400,000 | New | Q4 2025 | Feb 17, 2026 |
| STATE STREET CORP | History | Added to | 342,773 | 654 | 0.0% | 0.0% | 27 | +55,400 | 19.28% | Q4 2025 | Feb 13, 2026 |
| DIMENSIONAL FUND ADVISORS LP | History | Reduced | 296,480 | 566 | 0.0% | 0.0% | 28 | -52,809 | -15.12% | Q4 2025 | Feb 12, 2026 |
| Qube Research & Technologies Ltd | History | Added to | 290,234 | 554 | 0.0% | 0.0% | 29 | +174,261 | 150.26% | Q4 2025 | Feb 17, 2026 |
| Susquehanna Portfolio Strategies, LLC | History | No change | 272,053 | 519 | 0.01% | 0.01% | 30 | 0 | 0.0% | Q4 2025 | Feb 17, 2026 |
| Invesco Ltd. | History | Added to | 268,350 | 512 | 0.0% | 0.0% | 31 | +76,530 | 39.9% | Q4 2025 | Feb 19, 2026 |
| MARSHALL WACE, LLP | History | Added to | 265,027 | 506 | 0.0% | 0.0% | 32 | +158,752 | 149.38% | Q4 2025 | Feb 13, 2026 |
| FMR LLC | History | Added to | 254,406 | 485 | 0.0% | 0.0% | 33 | +43,058 | 20.37% | Q4 2025 | Feb 17, 2026 |
| LPL Financial LLC | History | Added to | 243,305 | 464 | 0.0% | 0.0% | 34 | +42,375 | 21.09% | Q4 2025 | Feb 11, 2026 |
| Hennion & Walsh Asset Management, Inc. | History | Added to | 237,137 | 452 | 0.02% | 0.02% | 35 | +32,104 | 15.66% | Q4 2025 | Jan 14, 2026 |
| BARCLAYS PLC | History | Added to | 219,204 | 418 | 0.0% | 0.0% | 36 | +176,142 | 409.04% | Q4 2025 | Feb 13, 2026 |
| ArrowMark Colorado Holdings LLC | History | No change | 204,505 | 390 | 0.01% | 0.01% | 37 | 0 | 0.0% | Q4 2025 | Feb 17, 2026 |
| NORTHERN TRUST CORP | History | Added to | 166,207 | 317 | 0.0% | 0.0% | 38 | +27,888 | 20.16% | Q4 2025 | Feb 17, 2026 |
| Man Group plc | History | Added to | 156,098 | 298 | 0.0% | 0.0% | 39 | +65,820 | 72.91% | Q4 2025 | Feb 17, 2026 |
| Squarepoint Ops LLC | History | Added to | 136,054 | 259 | 0.0% | 0.0% | 40 | +125,955 | 1247.2% | Q4 2025 | Feb 13, 2026 |
| Quadrature Capital Ltd | History | New | 133,112 | 254 | 0.0% | — | 41 | +133,112 | New | Q4 2025 | Feb 17, 2026 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | History | Added to | 131,100 | 250 | 0.01% | 0.0% | 42 | +51,200 | 64.08% | Q4 2025 | Feb 17, 2026 |
| Mariner, LLC | History | Reduced | 128,050 | 244 | 0.0% | 0.0% | 43 | -187 | -0.15% | Q4 2025 | Feb 13, 2026 |
| OMERS ADMINISTRATION Corp | History | New | 117,700 | 224 | 0.0% | — | 44 | +117,700 | New | Q4 2025 | Feb 13, 2026 |
| Hudson Bay Capital Management LP | History | New | 111,551 | 213 | 0.0% | — | 45 | +111,551 | New | Q4 2025 | Feb 13, 2026 |
| Atom Investors LP | History | New | 104,964 | 200 | 0.02% | — | 46 | +104,964 | New | Q4 2025 | Feb 17, 2026 |
| XTX Topco Ltd | History | Reduced | 104,458 | 199 | 0.01% | 0.02% | 47 | -45,504 | -30.34% | Q4 2025 | Feb 17, 2026 |
| Graham Capital Management, L.P. | History | Added to | 102,198 | 195 | 0.0% | 0.0% | 48 | +61,570 | 151.55% | Q4 2025 | Feb 17, 2026 |
| Vienna Powszechne Towarzystwo Emerytalne S.A. Vienna Insurance Group | History | No change | 85,000 | 162 | 0.08% | 0.11% | 49 | 0 | 0.0% | Q4 2025 | Feb 05, 2026 |
| AMERICAN CENTURY COMPANIES INC | History | Added to | 68,245 | 130 | 0.0% | 0.0% | 50 | +43,997 | 181.45% | Q4 2025 | Feb 13, 2026 |
| SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | History | No change | 67,617 | 129 | 0.0% | 0.01% | 51 | 0 | 0.0% | Q4 2025 | Feb 17, 2026 |
| Crestwood Advisors Group, LLC | History | No change | 66,536 | 127 | 0.0% | 0.0% | 52 | 0 | 0.0% | Q4 2025 | Feb 03, 2026 |
| ExodusPoint Capital Management, LP | History | New | 62,165 | 118 | 0.0% | — | 53 | +62,165 | New | Q4 2025 | Feb 17, 2026 |
| INTREPID FAMILY OFFICE LLC | History | Reduced | 55,000 | 105 | 0.09% | 0.13% | 54 | -15,000 | -21.43% | Q4 2025 | Feb 17, 2026 |
| D. E. Shaw & Co., Inc. | History | Added to | 52,879 | 100 | 0.0% | 0.0% | 55 | +41,016 | 345.75% | Q4 2025 | Feb 17, 2026 |
| UBS Group AG | History | Reduced | 52,752 | 100 | 0.0% | 0.0% | 56 | -8,898 | -14.43% | Q4 2025 | Jan 29, 2026 |
| CITIGROUP INC | History | Added to | 49,840 | 95 | 0.0% | 0.0% | 57 | +46,576 | 1426.96% | Q4 2025 | Feb 13, 2026 |
| Catalyst Funds Management Pty Ltd | History | No change | 42,500 | 81 | 0.02% | 0.01% | 58 | 0 | 0.0% | Q4 2025 | Feb 09, 2026 |
| GROUP ONE TRADING LLC | History | Added to | 38,994 | 74 | 0.0% | 0.0% | 59 | +26,562 | 213.66% | Q4 2025 | Feb 12, 2026 |
| Focus Partners Wealth | History | New | 38,187 | 72 | 0.0% | — | 60 | +38,187 | New | Q4 2025 | Feb 13, 2026 |
| Connor, Clark & Lunn Investment Management Ltd. | History | New | 37,721 | 72 | 0.0% | — | 61 | +37,721 | New | Q4 2025 | Feb 10, 2026 |
| Jefferies Financial Group Inc. | History | Reduced | 35,340 | 67 | 0.0% | 0.0% | 62 | -2,860 | -7.49% | Q4 2025 | Feb 09, 2026 |
| Lighthouse Investment Partners, LLC | History | New | 33,660 | 64 | 0.0% | — | 63 | +33,660 | New | Q4 2025 | Feb 17, 2026 |
| Callan Family Office, LLC | History | New | 31,743 | 60 | 0.0% | — | 64 | +31,743 | New | Q4 2025 | Feb 12, 2026 |
| SIMPLEX TRADING, LLC | History | Added to | 30,658 | 58 | 0.0% | 0.0% | 65 | +22,822 | 291.25% | Q4 2025 | Feb 11, 2026 |
| CANADA PENSION PLAN INVESTMENT BOARD | History | New | 29,500 | 56 | 0.0% | — | 66 | +29,500 | New | Q4 2025 | Feb 17, 2026 |
| FARALLON CAPITAL MANAGEMENT LLC | History | No change | 28,000 | 53 | 0.0% | 0.0% | 67 | 0 | 0.0% | Q4 2025 | Feb 17, 2026 |
| Tower Research Capital LLC (TRC) | History | Added to | 25,980 | 49 | 0.0% | 0.0% | 68 | +17,566 | 208.77% | Q4 2025 | Feb 17, 2026 |
| Cresset Asset Management, LLC | History | No change | 25,000 | 47 | 0.0% | 0.0% | 69 | 0 | 0.0% | Q4 2025 | Feb 17, 2026 |
| Engineers Gate Manager LP | History | Added to | 24,416 | 46 | 0.0% | 0.0% | 70 | +8,130 | 49.92% | Q4 2025 | Feb 17, 2026 |
| Corient Private Wealth LLC | History | Reduced | 21,387 | 40 | 0.0% | 0.0% | 71 | -1,315 | -5.79% | Q4 2025 | Mar 09, 2026 |
| Virtu Financial LLC | History | New | 20,655 | 39 | 0.0% | — | 72 | +20,655 | New | Q4 2025 | Feb 23, 2026 |
| Delta Investment Management, LLC | History | New | 20,000 | 38 | 0.01% | — | 73 | +20,000 | New | Q4 2025 | Jan 30, 2026 |
| EWA, LLC | History | Reduced | 16,889 | 32 | 0.01% | 0.01% | 74 | -2,621 | -13.43% | Q4 2025 | Feb 03, 2026 |
| China Universal Asset Management Co., Ltd. | History | Added to | 15,792 | 30 | 0.0% | 0.0% | 75 | +3,317 | 26.59% | Q4 2025 | Jan 29, 2026 |
| Vanguard Personalized Indexing Management, LLC | History | Added to | 15,224 | 29 | 0.0% | 0.0% | 76 | +650 | 4.46% | Q4 2025 | Feb 13, 2026 |
| PRUDENTIAL FINANCIAL INC | History | Added to | 15,050 | 28 | 0.0% | 0.0% | 77 | +750 | 5.24% | Q4 2025 | Feb 13, 2026 |
| R Squared Ltd | History | Reduced | 13,674 | 26 | 0.01% | 0.02% | 79 | -4,206 | -23.52% | Q4 2025 | Jan 30, 2026 |
| HSBC HOLDINGS PLC | History | No change | 13,629 | 26 | 0.0% | 0.0% | 78 | 0 | 0.0% | Q4 2025 | Mar 20, 2026 |
| Northern Lights Advisors, Inc. | History | New | 12,930 | 24 | 0.02% | — | 82 | +12,930 | New | Q4 2025 | Apr 20, 2026 |
| Jain Global LLC | History | New | 12,762 | 24 | 0.0% | — | 81 | +12,762 | New | Q4 2025 | Feb 17, 2026 |
| PRICE T ROWE ASSOCIATES INC /MD/ | History | No change | 12,400 | 24 | 0.0% | 0.0% | 80 | 0 | 0.0% | Q4 2025 | Feb 17, 2026 |
| NINE MASTS CAPITAL Ltd | History | New | 11,472 | 21 | 0.0% | — | 83 | +11,472 | New | Q4 2025 | Feb 10, 2026 |
| Bronte Capital Management Pty Ltd. | History | New | 10,033 | 19 | 0.0% | — | 84 | +10,033 | New | Q4 2025 | Feb 03, 2026 |
| Blackston Financial Advisory Group, LLC | History | New | 10,000 | 19 | 0.01% | — | 86 | +10,000 | New | Q4 2025 | Feb 06, 2026 |
| Ethic Inc. | History | Reduced | 10,278 | 19 | 0.0% | 0.0% | 85 | -230 | -2.19% | Q4 2025 | Feb 03, 2026 |
| Simplicity Wealth,LLC | History | Reduced | 10,202 | 19 | 0.0% | 0.0% | 87 | -11 | -0.11% | Q4 2025 | Jan 30, 2026 |
| Abel Hall, LLC | History | No change | 10,140 | 19 | 0.0% | 0.01% | 88 | 0 | 0.0% | Q4 2025 | Feb 17, 2026 |
| JPMORGAN CHASE & CO | History | Added to | 5,945 | 11 | 0.0% | 0.0% | 89 | +1,516 | 34.23% | Q4 2025 | Feb 11, 2026 |
| Mirae Asset Global Investments Co., Ltd. | History | Added to | 4,709 | 8 | 0.0% | 0.0% | 90 | +1,958 | 71.17% | Q4 2025 | Jan 26, 2026 |
| OSAIC HOLDINGS, INC. | History | Added to | 4,544 | 8 | 0.0% | 0.0% | 91 | +14 | 0.31% | Q4 2025 | Feb 17, 2026 |
| NBC SECURITIES, INC. | History | New | 4,000 | 7 | 0.0% | — | 92 | +4,000 | New | Q4 2025 | Jan 29, 2026 |
| RHUMBLINE ADVISERS | History | No change | 2,716 | 5 | 0.0% | 0.0% | 93 | 0 | 0.0% | Q4 2025 | Feb 13, 2026 |
| BNP PARIBAS FINANCIAL MARKETS | History | Reduced | 2,161 | 4 | 0.0% | 0.0% | 94 | -78,645 | -97.33% | Q4 2025 | Feb 10, 2026 |
| GF FUND MANAGEMENT CO. LTD. | History | Added to | 1,903 | 3 | 0.0% | 0.0% | 95 | +440 | 30.08% | Q4 2025 | Jan 27, 2026 |
| Federation des caisses Desjardins du Quebec | History | New | 1,000 | 1 | 0.0% | — | 97 | +1,000 | New | Q4 2025 | Feb 12, 2026 |
| ROYAL BANK OF CANADA | History | New | 671 | 1 | 0.0% | — | 96 | +671 | New | Q4 2025 | Feb 17, 2026 |
| TANG CAPITAL MANAGEMENT LLC | History | Closed out | 0 | 0 | — | 0.08% | — | -900,000 | -100.0% | Q3 2025 | Nov 14, 2025 |
| Shay Capital LLC | History | Closed out | 0 | 0 | — | 0.08% | — | -420,000 | -100.0% | Q3 2025 | Nov 14, 2025 |
| DIADEMA PARTNERS LP | History | Closed out | 0 | 0 | — | 0.08% | — | -140,700 | -100.0% | Q3 2025 | Nov 14, 2025 |
| ALGERT GLOBAL LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -106,300 | -100.0% | Q3 2025 | Nov 14, 2025 |
| State of Wyoming | History | Closed out | 0 | 0 | — | 0.02% | — | -82,509 | -100.0% | Q3 2025 | Nov 04, 2025 |
| Voleon Capital Management LP | History | Closed out | 0 | 0 | — | 0.0% | — | -28,420 | -100.0% | Q3 2025 | Nov 14, 2025 |
| COMMONWEALTH EQUITY SERVICES, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -20,510 | -100.0% | Q3 2025 | Oct 22, 2025 |
| Caitong International Asset Management Co., Ltd | History | Closed out | 0 | 0 | — | 0.03% | — | -19,146 | -100.0% | Q3 2025 | Nov 19, 2025 |
| CAPTRUST FINANCIAL ADVISORS | History | Closed out | 0 | 0 | — | 0.0% | — | -14,889 | -100.0% | Q3 2025 | Nov 19, 2025 |
| B. Riley Wealth Advisors, Inc. | History | Closed out | 0 | 0 | — | 0.0% | — | -11,000 | -100.0% | Q3 2025 | Oct 31, 2025 |
| JFS WEALTH ADVISORS, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -1,000 | -100.0% | Q3 2025 | Nov 10, 2025 |
| OPTIMA CAPITAL LLC | History | New | 226 | 0 | — | — | — | +226 | New | Q4 2025 | Jan 23, 2026 |
| CWM, LLC | History | Closed out | 0 | 0 | — | — | — | -146 | -100.0% | Q3 2025 | Oct 15, 2025 |
| Wealthspire Advisors, LLC | History | Closed out | 0 | 0 | — | — | — | -100 | -100.0% | Q3 2025 | Nov 14, 2025 |
| Advisory Services Network, LLC | History | Closed out | 0 | 0 | — | — | — | -74 | -100.0% | Q3 2025 | Nov 18, 2025 |
| SBI Securities Co., Ltd. | History | Reduced | 100 | 0 | — | — | — | -52 | -34.21% | Q4 2025 | Feb 03, 2026 |
| Arax Advisory Partners | History | Reduced | 19 | 0 | — | — | — | -36 | -65.45% | Q4 2025 | Feb 13, 2026 |
| IFP Advisors, Inc | History | Closed out | 0 | 0 | — | — | — | -17 | -100.0% | Q3 2025 | Feb 06, 2026 |
| NISA INVESTMENT ADVISORS, LLC | History | No change | 156 | 0 | — | — | — | 0 | 0.0% | Q4 2025 | Jan 15, 2026 |