Design Therapeutics, Inc. - DSGN

Detailed investor-level table based on 13F positions.

Shareholders (13F)

Quarter: Q2 2026 · Compare: Q1 2026
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
SR ONE CAPITAL MANAGEMENT, LP History No change 6,526,476 94,438 9.09% 7.59% 1 0 0.0% Q2 2026 Aug 12, 2026
Logos Global Management LP History Added to 3,000,000 43,410 1.87% 1.04% 2 +1,050,000 53.85% Q2 2026 Aug 14, 2026
BAKER BROS. ADVISORS LP History Added to 2,678,430 38,756 0.19% 0.16% 3 +92,452 3.58% Q2 2026 Aug 14, 2026
DRIEHAUS CAPITAL MANAGEMENT LLC History Added to 2,661,115 38,506 0.22% 0.14% 4 +916,128 52.5% Q2 2026 Aug 14, 2026
BlackRock, Inc. History Added to 2,660,024 38,490 0.0% 0.0% 5 +526,260 24.66% Q2 2026 Aug 07, 2026
Caption Management, LLC History Added to 2,618,098 37,883 0.18% 0.01% 6 +2,531,390 2919.44% Q2 2026 Aug 14, 2026
Point72 Asset Management, L.P. History Reduced 2,366,453 34,242 0.04% 0.04% 7 -356,301 -13.09% Q2 2026 Aug 14, 2026
Trails Edge Capital Partners, LP History Added to 2,001,282 28,958 4.6% 2.08% 8 +1,149,269 134.89% Q2 2026 Aug 14, 2026
Frazier Life Sciences Management, L.P. History New 1,809,854 26,188 0.57% 9 +1,809,854 New Q2 2026 Aug 14, 2026
Vivo Capital, LLC History No change 1,612,903 23,338 2.13% 1.43% 10 0 0.0% Q2 2026 Aug 14, 2026
VANGUARD CAPITAL MANAGEMENT LLC History Added to 1,571,022 22,732 0.0% 0.0% 11 +221,172 16.38% Q2 2026 Aug 13, 2026
Almitas Capital LLC History Reduced 1,026,893 14,859 3.56% 3.68% 12 -503,442 -32.9% Q2 2026 Aug 14, 2026
GEODE CAPITAL MANAGEMENT, LLC History Added to 958,417 13,871 0.0% 0.0% 13 +265,899 38.4% Q2 2026 Aug 12, 2026
Sofinnova Investments, Inc. History New 865,135 12,518 0.65% 14 +865,135 New Q2 2026 Aug 14, 2026
FMR LLC History Reduced 776,462 11,235 0.0% 0.0% 15 -21,949 -2.75% Q2 2026 Aug 13, 2026
MORGAN STANLEY History Added to 765,425 11,075 0.0% 0.0% 16 +108,860 16.58% Q2 2026 Aug 13, 2026
STATE STREET CORP History Added to 736,221 10,653 0.0% 0.0% 17 +76,646 11.62% Q2 2026 Aug 07, 2026
Woodline Partners LP History Reduced 700,354 10,134 0.03% 0.04% 18 -261,147 -27.16% Q2 2026 Aug 14, 2026
DIMENSIONAL FUND ADVISORS LP History Added to 694,743 10,051 0.0% 0.0% 19 +262,903 60.88% Q2 2026 Aug 11, 2026
GOLDMAN SACHS GROUP INC History Added to 656,584 9,500 0.0% 0.0% 20 +151,866 30.09% Q2 2026 Aug 14, 2026
JACOBS LEVY EQUITY MANAGEMENT, INC History Added to 565,597 8,184 0.03% 0.01% 21 +276,212 95.45% Q2 2026 Aug 14, 2026
ACADIAN ASSET MANAGEMENT LLC History Reduced 537,479 7,774 0.01% 0.01% 22 -79,002 -12.81% Q2 2026 Aug 13, 2026
Siren, L.L.C. History New 523,212 7,570 0.15% 23 +523,212 New Q2 2026 Aug 13, 2026
Qube Research & Technologies Ltd History Added to 437,079 6,324 0.01% 0.0% 24 +402,896 1178.64% Q2 2026 Aug 14, 2026
RENAISSANCE TECHNOLOGIES LLC History Reduced 387,913 5,613 0.01% 0.01% 25 -20,287 -4.97% Q2 2026 Aug 13, 2026
KENNEDY CAPITAL MANAGEMENT LLC History Added to 384,036 5,557 0.1% 0.06% 26 +112,482 41.42% Q2 2026 Aug 14, 2026
NORTHERN TRUST CORP History Added to 353,197 5,110 0.0% 0.0% 27 +52,918 17.62% Q2 2026 Aug 13, 2026
ALGERT GLOBAL LLC History Added to 296,085 4,284 0.05% 0.03% 28 +91,346 44.62% Q2 2026 Aug 13, 2026
ACUTA CAPITAL PARTNERS, LLC History Added to 282,564 4,088 2.85% 1.09% 29 +136,664 93.67% Q2 2026 Aug 14, 2026
CHARLES SCHWAB INVESTMENT MANAGEMENT INC History Added to 271,264 3,925 0.0% 0.0% 30 +29,779 12.33% Q2 2026 Aug 14, 2026
VANGUARD PORTFOLIO MANAGEMENT LLC History Added to 251,442 3,638 0.0% 0.0% 31 +112,877 81.46% Q2 2026 Aug 13, 2026
VANGUARD FIDUCIARY TRUST CO History Added to 230,202 3,331 0.0% 0.0% 32 +34,544 17.66% Q2 2026 Aug 13, 2026
PRUDENTIAL FINANCIAL INC History Added to 224,170 3,243 0.0% 0.0% 33 +178,360 389.35% Q2 2026 Aug 12, 2026
D. E. Shaw & Co., Inc. History Reduced 195,645 2,830 0.0% 0.0% 34 -274,625 -58.4% Q2 2026 Aug 14, 2026
Eversept Partners, LP History New 190,000 2,749 0.14% 35 +190,000 New Q2 2026 Aug 14, 2026
KVP Capital Advisors, LP History New 185,000 2,676 1.96% 36 +185,000 New Q2 2026 Aug 13, 2026
J. Goldman & Co LP History New 176,770 2,557 0.07% 37 +176,770 New Q2 2026 Aug 14, 2026
MILLENNIUM MANAGEMENT LLC History Added to 147,714 2,137 0.0% 0.0% 38 +38,786 35.61% Q2 2026 Aug 14, 2026
RAYMOND JAMES FINANCIAL INC History Added to 138,521 2,004 0.0% 0.0% 39 +30,072 27.73% Q2 2026 Aug 14, 2026
BALYASNY ASSET MANAGEMENT L.P. History New 111,103 1,607 0.0% 40 +111,103 New Q2 2026 Aug 14, 2026
Elmind Capital, LP History Reduced 107,900 1,561 0.39% 0.63% 41 -100,000 -48.1% Q2 2026 Aug 14, 2026
Nuveen, LLC History Reduced 104,734 1,515 0.0% 0.0% 42 -22,081 -17.41% Q2 2026 Aug 11, 2026
DAFNA Capital Management LLC History New 102,600 1,484 0.28% 43 +102,600 New Q2 2026 Aug 14, 2026
CITADEL ADVISORS LLC History Reduced 95,871 1,387 0.0% 0.0% 44 -135,642 -58.59% Q2 2026 Sep 02, 2026
Bank of New York Mellon Corp History Added to 92,069 1,332 0.0% 0.0% 45 +12,424 15.6% Q2 2026 Aug 06, 2026
China Universal Asset Management Co., Ltd. History Added to 89,940 1,301 0.08% 0.03% 46 +54,831 156.17% Q2 2026 Jul 24, 2026
SummitTX Capital, L.P. History New 80,663 1,167 0.03% 47 +80,663 New Q2 2026 Aug 14, 2026
AMERICAN CENTURY COMPANIES INC History Added to 76,825 1,111 0.0% 0.0% 48 +11,187 17.04% Q2 2026 Aug 12, 2026
Palumbo Wealth Management LLC History Added to 71,744 1,038 0.22% 0.19% 49 +336 0.47% Q2 2026 Aug 12, 2026
AQR CAPITAL MANAGEMENT LLC History Added to 71,114 1,029 0.0% 0.0% 50 +45,157 173.97% Q2 2026 Aug 14, 2026
AMERIPRISE FINANCIAL INC History Added to 67,598 978 0.0% 0.0% 51 +32,608 93.19% Q2 2026 Aug 14, 2026
Russell Investments Group, Ltd. History Added to 66,859 967 0.0% 0.0% 52 +41,422 162.84% Q2 2026 Aug 06, 2026
ALPS ADVISORS INC History Added to 63,391 917 0.0% 0.0% 53 +13,182 26.25% Q2 2026 Jul 29, 2026
STATE OF WISCONSIN INVESTMENT BOARD History Added to 59,249 857 0.0% 0.0% 54 +10,035 20.39% Q2 2026 Aug 14, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History New 55,650 805 0.0% 55 +55,650 New Q2 2026 Aug 14, 2026
STRS OHIO History Added to 50,500 730 0.0% 0.0% 56 +5,800 12.98% Q2 2026 Jul 30, 2026
Verdad Advisers, LP History Reduced 47,557 688 0.66% 1.11% 57 -44,753 -48.48% Q2 2026 Aug 14, 2026
BANK OF AMERICA CORP /DE/ History Added to 43,728 632 0.0% 0.0% 58 +20,464 87.96% Q2 2026 Aug 14, 2026
ExodusPoint Capital Management, LP History New 41,286 597 0.0% 59 +41,286 New Q2 2026 Aug 14, 2026
RHUMBLINE ADVISERS History Added to 38,132 551 0.0% 0.0% 60 +3,272 9.39% Q2 2026 Aug 11, 2026
Vanguard Global Advisers, LLC History Added to 35,534 514 0.0% 0.0% 61 +23,695 200.14% Q2 2026 Aug 13, 2026
UBS Group AG History Added to 34,761 502 0.0% 0.0% 62 +17,670 103.39% Q2 2026 Aug 13, 2026
Susquehanna Portfolio Strategies, LLC History New 33,375 482 0.01% 63 +33,375 New Q2 2026 Aug 14, 2026
TWO SIGMA INVESTMENTS, LP History Added to 32,925 476 0.0% 0.0% 64 +16,625 101.99% Q2 2026 Aug 14, 2026
CANADA PENSION PLAN INVESTMENT BOARD History Reduced 32,600 471 0.0% 0.0% 65 -27,800 -46.03% Q2 2026 Aug 14, 2026
OPPENHEIMER & CO INC History New 32,087 464 0.0% 66 +32,087 New Q2 2026 Aug 03, 2026
ALLIANCEBERNSTEIN L.P. History Reduced 43,230 459 0.0% 0.0% 67 -2,890 -6.27% Q2 2026 Aug 14, 2026
DEUTSCHE BANK AG\ History Added to 30,613 442 0.0% 0.0% 68 +9,969 48.29% Q2 2026 Aug 07, 2026
Virtus Investment Advisers, LLC History New 29,827 431 0.1% 69 +29,827 New Q2 2026 Aug 11, 2026
Squarepoint Ops LLC History Reduced 29,630 428 0.0% 0.0% 70 -56,487 -65.59% Q2 2026 Aug 14, 2026
Trexquant Investment LP History Reduced 28,150 407 0.0% 0.01% 71 -88,961 -75.96% Q2 2026 Aug 14, 2026
WELLS FARGO & COMPANY/MN History Added to 28,072 406 0.0% 0.0% 72 +19,045 210.98% Q2 2026 Aug 14, 2026
Corient Private Wealth LP History No change 27,169 393 0.0% 0.0% 73 0 0.0% Q2 2026 Aug 27, 2026
BRIDGEWAY CAPITAL MANAGEMENT, LLC History Reduced 27,000 390 0.01% 0.01% 74 -25,000 -48.08% Q2 2026 Aug 14, 2026
Quantinno Capital Management LP History Added to 26,901 389 0.0% 0.0% 75 +12,773 90.41% Q2 2026 Aug 13, 2026
PRICE T ROWE ASSOCIATES INC /MD/ History Added to 25,606 371 0.0% 0.0% 76 +9,236 56.42% Q2 2026 Aug 14, 2026
SEI INVESTMENTS CO History Reduced 22,740 329 0.0% 0.0% 77 -110,463 -82.93% Q2 2026 Aug 14, 2026
XTX Topco Ltd History Reduced 22,383 323 0.0% 0.01% 78 -38,556 -63.27% Q2 2026 Aug 14, 2026
AlphaCentric Advisors LLC History Added to 21,537 311 0.26% 0.22% 79 +306 1.44% Q2 2026 Jul 24, 2026
Invesco Ltd. History Reduced 21,429 310 0.0% 0.0% 80 -120,491 -84.9% Q2 2026 Aug 14, 2026
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO History Added to 20,700 299 0.0% 0.0% 81 +5,507 36.25% Q2 2026 Aug 17, 2026
MetLife Investment Management, LLC History Added to 20,609 298 0.0% 0.0% 82 +5,360 35.15% Q2 2026 Aug 13, 2026
WELLINGTON MANAGEMENT GROUP LLP History New 19,400 280 0.0% 83 +19,400 New Q2 2026 Aug 14, 2026
JPMORGAN CHASE & CO History Added to 16,904 240 0.0% 0.0% 84 +2,770 19.6% Q2 2026 Aug 12, 2026
Creative Planning History New 15,844 229 0.0% 86 +15,844 New Q2 2026 Aug 13, 2026
CITIGROUP INC History Added to 15,880 229 0.0% 0.0% 85 +11,617 272.51% Q2 2026 Aug 03, 2026
NISA INVESTMENT ADVISORS, LLC History No change 14,824 214 0.0% 0.0% 87 0 0.0% Q2 2026 Aug 10, 2026
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. History Added to 14,171 205 0.0% 0.0% 88 +2,808 24.71% Q2 2026 Aug 14, 2026
Y-Intercept (Hong Kong) Ltd History New 12,910 186 0.0% 89 +12,910 New Q2 2026 Jul 13, 2026
SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC History New 12,553 181 0.0% 90 +12,553 New Q2 2026 Aug 14, 2026
ROYAL BANK OF CANADA History Added to 12,254 178 0.0% 0.0% 91 +888 7.81% Q2 2026 Aug 14, 2026
BARCLAYS PLC History Reduced 11,707 169 0.0% 0.0% 92 -44,083 -79.02% Q2 2026 Aug 14, 2026
NEW YORK STATE COMMON RETIREMENT FUND History Added to 10,826 156 0.0% 0.0% 93 +8,800 434.35% Q2 2026 Jul 29, 2026
GSA CAPITAL PARTNERS LLP History New 10,328 149 0.01% 94 +10,328 New Q2 2026 Aug 06, 2026
Police & Firemen's Retirement System of New Jersey History Added to 9,849 142 0.0% 0.0% 95 +3,251 49.27% Q2 2026 Jul 23, 2026
BNP PARIBAS FINANCIAL MARKETS History Reduced 5,751 83 0.0% 0.0% 96 -44,521 -88.56% Q2 2026 Aug 13, 2026
Clearstead Advisors, LLC History Added to 5,610 81 0.0% 0.0% 97 +5,000 819.67% Q2 2026 Aug 06, 2026
Tower Research Capital LLC (TRC) History Added to 4,908 71 0.0% 0.0% 98 +3,363 217.67% Q2 2026 Aug 11, 2026
Rockefeller Capital Management L.P. History No change 3,684 53 0.0% 0.0% 99 0 0.0% Q2 2026 Aug 13, 2026
CAZ INVESTMENTS LP History No change 3,500 50 0.05% 0.04% 100 0 0.0% Q2 2026 Aug 13, 2026
Zurcher Kantonalbank (Zurich Cantonalbank) History Added to 3,025 43 0.0% 0.0% 102 +1,431 89.77% Q2 2026 Aug 11, 2026
Legal & General Group Plc History Added to 2,987 43 0.0% 0.0% 101 +910 43.81% Q2 2026 Aug 14, 2026
Ameritas Investment Partners, Inc. History Added to 2,793 40 0.0% 0.0% 103 +223 8.68% Q2 2026 Aug 13, 2026
Mirae Asset Global Investments Co., Ltd. History Reduced 2,793 40 0.0% 0.0% 104 -178 -5.99% Q2 2026 Jul 22, 2026
State of Wyoming History New 2,566 37 0.0% 105 +2,566 New Q2 2026 Aug 06, 2026
PNC FINANCIAL SERVICES GROUP, INC. History No change 1,816 26 0.0% 0.0% 106 0 0.0% Q2 2026 Aug 07, 2026
GAMMA Investing LLC History Reduced 1,450 20 0.0% 0.0% 107 -22 -1.49% Q2 2026 Jul 07, 2026
Caitong International Asset Management Co., Ltd History Added to 1,259 18 0.0% 108 +1,258 125800.0% Q2 2026 Aug 04, 2026
GF FUND MANAGEMENT CO. LTD. History Reduced 1,209 17 0.0% 0.0% 109 -62 -4.88% Q2 2026 Aug 07, 2026
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC History No change 1,143 16 0.0% 0.0% 110 0 0.0% Q2 2026 Aug 13, 2026
Allied Private Wealth LLC History New 880 13 0.01% 111 +880 New Q2 2026 Jul 09, 2026
SIMPLEX TRADING, LLC History New 772 11 0.0% 112 +772 New Q2 2026 Aug 12, 2026
Private Wealth Management Group, LLC History No change 533 7 0.0% 0.0% 113 0 0.0% Q2 2026 Jul 27, 2026
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM History Reduced 335 4 0.0% 0.0% 114 -957 -74.07% Q2 2026 Aug 24, 2026
CWM, LLC History No change 423 4 0.0% 0.0% 115 0 0.0% Q1 2026 May 14, 2026
OSAIC HOLDINGS, INC. History Reduced 225 3 0.0% 0.0% 117 -81 -26.47% Q2 2026 Aug 14, 2026
MassMutual Private Wealth & Trust, FSB History No change 239 3 0.0% 0.0% 116 0 0.0% Q2 2026 Jul 02, 2026
Stone House Investment Management, LLC History No change 239 3 0.0% 0.0% 118 0 0.0% Q2 2026 Aug 05, 2026
Physician Wealth Advisors, Inc. History No change 268 3 0.0% 0.0% 119 0 0.0% Q2 2026 Jul 20, 2026
Arax Advisory Partners History New 180 2 0.0% 122 +180 New Q2 2026 Aug 10, 2026
Optiver Holding B.V. History Reduced 160 2 0.0% 0.0% 121 -64 -28.57% Q2 2026 Aug 12, 2026
Larson Financial Group LLC History No change 181 2 0.0% 0.0% 120 0 0.0% Q2 2026 Aug 14, 2026
Sterling Capital Management LLC History Reduced 108 1 0.0% 0.0% 124 -683 -86.35% Q2 2026 Jul 28, 2026
Versant Capital Management, Inc History New 86 1 0.0% 126 +86 New Q2 2026 Jul 02, 2026
NATIONAL BANK OF CANADA /FI/ History Added to 83 1 0.0% 123 +74 822.22% Q2 2026 Aug 10, 2026
Allworth Financial LP History Reduced 96 1 0.0% 0.0% 125 -34 -26.15% Q2 2026 Aug 11, 2026
RA CAPITAL MANAGEMENT, L.P. History Closed out 0 0 0.34% -2,972,973 -100.0% Q2 2026 Aug 14, 2026
Kynam Capital Management, LP History Closed out 0 0 0.51% -784,606 -100.0% Q2 2026 Aug 14, 2026
MARSHALL WACE, LLP History Closed out 0 0 0.0% -151,008 -100.0% Q2 2026 Aug 13, 2026
Lynx1 Capital Management LP History Closed out 0 0 0.2% -119,516 -100.0% Q2 2026 Aug 13, 2026
JANE STREET GROUP, LLC History Closed out 0 0 0.0% -103,902 -100.0% Q2 2026 Aug 14, 2026
Informed Momentum Co LLC History Closed out 0 0 0.1% -78,949 -100.0% Q2 2026 Aug 13, 2026
Velan Capital Investment Management LP History Closed out 0 0 0.13% -20,000 -100.0% Q2 2026 Aug 14, 2026
Engineers Gate Manager LP History Closed out 0 0 0.0% -16,090 -100.0% Q2 2026 Aug 14, 2026
Brevan Howard Capital Management LP History Closed out 0 0 0.0% -15,294 -100.0% Q2 2026 Aug 14, 2026
Dynamic Technology Lab Private Ltd History Closed out 0 0 0.03% -14,749 -100.0% Q2 2026 Aug 13, 2026
Mariner, LLC History Closed out 0 0 0.0% -13,066 -100.0% Q2 2026 Aug 13, 2026
Baader Bank Aktiengesellschaft History Closed out 0 0 0.01% -12,792 -100.0% Q2 2026 Jul 23, 2026
MIRABELLA FINANCIAL SERVICES LLP History Closed out 0 0 0.01% -11,814 -100.0% Q2 2026 Jul 31, 2026
ADAR1 Capital Management, LLC History Closed out 0 0 0.01% -10,000 -100.0% Q2 2026 Aug 14, 2026
Farther Finance Advisors, LLC History Reduced 20 0 0.0% -366 -94.82% Q2 2026 Jul 17, 2026
Silver Grove Financial Group, Inc. History New 58 0 +58 New Q2 2026 Aug 13, 2026
Root Financial Partners, LLC History Closed out 0 0 -38 -100.0% Q2 2026 Jul 29, 2026
US BANCORP \DE\ History Reduced 26 0 -35 -57.38% Q2 2026 Aug 12, 2026
Quarry LP History New 31 0 +31 New Q2 2026 Aug 14, 2026
True Wealth Design, LLC History Added to 18 0 +17 1700.0% Q2 2026 Jul 16, 2026
EverSource Wealth Advisors, LLC History Added to 25 0 +15 150.0% Q2 2026 Jul 24, 2026
SBI Securities Co., Ltd. History New 10 0 +10 New Q2 2026 Jul 22, 2026
MAI Capital Management History Closed out 0 0 -8 -100.0% Q2 2026 Aug 14, 2026
SJS Investment Consulting Inc. History New 4 0 +4 New Q2 2026 Jul 22, 2026
ROTHSCHILD INVESTMENT LLC History Reduced 22 0 -1 -4.35% Q2 2026 Aug 06, 2026
Capital Advisors, Ltd. LLC History No change 12 0 0 0.0% Q2 2026 Jul 16, 2026
Essential Partners LLC History No change 1 0 0 0.0% Q2 2026 Aug 10, 2026