Maze Therapeutics, Inc. - MAZE

Detailed investor-level table based on 13F positions.
Early Q1 2026 data: only 1 institutional holders reported so far. The full shareholder list will grow as more funds file with the SEC.

Shareholders (13F)

Quarter: Q4 2025 · Compare: Q3 2025
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
Frazier Life Sciences Management, L.P. History No change 4,567,274 189,222 5.08% 3.55% 1 0 0.0% Q4 2025 Feb 13, 2026
TRV GP IV, LLC History Reduced 4,473,958 185,356 72.65% 57.49% 2 -1,600,000 -26.34% Q4 2025 Feb 13, 2026
Deep Track Capital, LP History Added to 4,246,440 175,930 3.14% 2.86% 3 +297,530 7.53% Q4 2025 Feb 13, 2026
ARCH Venture Management, LLC History No change 4,120,053 170,693 26.19% 21.7% 4 0 0.0% Q4 2025 Feb 17, 2026
JANUS HENDERSON GROUP PLC History Added to 3,142,587 130,197 0.06% 0.01% 5 +2,390,713 317.97% Q4 2025 Feb 17, 2026
BlackRock, Inc. History Added to 2,287,155 94,756 0.0% 0.0% 6 +971,139 73.79% Q4 2025 Feb 12, 2026
a16z Capital Management, L.L.C. History No change 1,702,225 70,523 4.46% 3.16% 7 0 0.0% Q4 2025 Feb 17, 2026
VANGUARD GROUP INC History Added to 1,697,015 70,307 0.0% 0.0% 8 +362,060 27.12% Q4 2025 Jan 29, 2026
VR Adviser, LLC History Added to 1,548,569 64,157 3.17% 1.8% 9 +317,800 25.82% Q4 2025 Feb 17, 2026
Alphabet Inc. History Reduced 1,388,583 57,528 2.23% 2.6% 10 -1,023,888 -42.44% Q4 2025 Feb 13, 2026
General Catalyst Group Management, LLC History No change 1,035,910 42,917 19.35% 0.88% 11 0 0.0% Q4 2025 Feb 17, 2026
Woodline Partners LP History No change 1,035,229 42,889 0.17% 0.13% 12 0 0.0% Q4 2025 Feb 17, 2026
TRV GP V, LLC History No change 950,800 39,391 9.18% 6.97% 13 0 0.0% Q4 2025 Feb 13, 2026
Logos Global Management LP History Reduced 950,000 39,358 2.38% 2.85% 14 -277,300 -22.59% Q4 2025 Feb 17, 2026
Bellevue Group AG History New 887,708 36,777 0.7% 15 +887,708 New Q4 2025 Feb 17, 2026
MARSHALL WACE, LLP History Added to 847,472 35,110 0.03% 0.02% 16 +69,771 8.97% Q4 2025 Feb 13, 2026
ArrowMark Colorado Holdings LLC History Added to 767,383 31,792 0.7% 0.26% 17 +222,251 40.77% Q4 2025 Feb 17, 2026
Casdin Capital, LLC History No change 758,857 31,439 1.95% 1.64% 18 0 0.0% Q4 2025 Feb 17, 2026
FMR LLC History Added to 728,605 30,186 0.0% 0.0% 19 +72,991 11.13% Q4 2025 Feb 17, 2026
Ikarian Capital, LLC History Reduced 644,680 26,709 2.09% 1.94% 20 -96,145 -12.98% Q4 2025 Feb 18, 2026
Caligan Partners LP History New 550,191 22,794 1.88% 21 +550,191 New Q4 2025 Feb 17, 2026
STATE STREET CORP History Added to 533,005 22,082 0.0% 0.0% 22 +148,303 38.55% Q4 2025 Feb 13, 2026
GEODE CAPITAL MANAGEMENT, LLC History Added to 527,281 21,850 0.0% 0.0% 23 +53,732 11.35% Q4 2025 Feb 09, 2026
Foresite Capital Management IV, LLC History No change 522,657 21,653 9.43% 7.42% 24 0 0.0% Q4 2025 Feb 17, 2026
Squadron Capital Management LLC History New 490,000 20,300 8.6% 25 +490,000 New Q4 2025 Feb 17, 2026
BESSEMER GROUP INC History No change 481,790 19,961 0.03% 0.02% 26 0 0.0% Q4 2025 Feb 05, 2026
Matrix Capital Management Company, LP History Reduced 480,000 19,886 34.51% 40.17% 27 -1,173,684 -70.97% Q4 2025 Feb 13, 2026
HHLR ADVISORS, LTD. History No change 457,535 18,955 0.61% 0.29% 28 0 0.0% Q4 2025 Feb 17, 2026
CITADEL ADVISORS LLC History New 448,217 18,569 0.0% 29 +448,217 New Q4 2025 Feb 17, 2026
BOOTHBAY FUND MANAGEMENT, LLC History Added to 409,372 16,960 0.25% 0.13% 30 +57,497 16.34% Q4 2025 Feb 17, 2026
DRIEHAUS CAPITAL MANAGEMENT LLC History No change 378,015 15,661 0.11% 0.07% 31 0 0.0% Q4 2025 Feb 17, 2026
EVENTIDE ASSET MANAGEMENT, LLC History New 324,041 13,425 0.21% 32 +324,041 New Q4 2025 Feb 13, 2026
WASHINGTON UNIVERSITY History Added to 280,802 11,633 5.88% 3.06% 33 +70,121 33.28% Q4 2025 Jan 16, 2026
MORGAN STANLEY History Added to 258,086 10,692 0.0% 0.0% 34 +45,324 21.3% Q4 2025 Feb 13, 2026
Mass General Brigham, Inc History New 239,994 9,942 1.23% 35 +239,994 New Q4 2025 Jan 27, 2026
Parkman Healthcare Partners LLC History Added to 209,266 8,669 0.83% 0.54% 36 +9,266 4.63% Q4 2025 Feb 17, 2026
BALYASNY ASSET MANAGEMENT L.P. History Reduced 199,212 8,253 0.01% 0.01% 37 -234,513 -54.07% Q4 2025 Feb 17, 2026
Alyeska Investment Group, L.P. History Added to 196,124 8,125 0.02% 0.01% 38 +71,124 56.9% Q4 2025 Feb 13, 2026
Ensign Peak Advisors, Inc History Added to 185,794 7,697 0.01% 0.0% 39 +115,129 162.92% Q4 2025 Feb 12, 2026
ADAR1 Capital Management, LLC History Added to 179,532 7,438 0.55% 0.06% 40 +153,487 589.31% Q4 2025 Feb 18, 2026
NORTHERN TRUST CORP History Reduced 176,259 7,302 0.0% 0.0% 41 -631 -0.36% Q4 2025 Feb 17, 2026
CHARLES SCHWAB INVESTMENT MANAGEMENT INC History Added to 175,969 7,290 0.0% 0.0% 42 +8,041 4.79% Q4 2025 Feb 13, 2026
TCG Crossover Management, LLC History New 173,816 7,201 0.24% 43 +173,816 New Q4 2025 Feb 17, 2026
HighVista Strategies LLC History New 170,353 7,057 1.82% 44 +170,353 New Q4 2025 Feb 17, 2026
MILLENNIUM MANAGEMENT LLC History New 154,470 6,399 0.0% 45 +154,470 New Q4 2025 Feb 17, 2026
Invesco Ltd. History Added to 134,033 5,552 0.0% 0.0% 46 +1,971 1.49% Q4 2025 Feb 19, 2026
STEMPOINT CAPITAL LP History New 125,877 5,215 0.89% 47 +125,877 New Q4 2025 Feb 17, 2026
Freestone Grove Partners LP History New 118,876 4,925 0.04% 48 +118,876 New Q4 2025 Feb 17, 2026
PRICE T ROWE ASSOCIATES INC /MD/ History Added to 115,711 4,794 0.0% 0.0% 49 +105,237 1004.75% Q4 2025 Feb 17, 2026
GOLDMAN SACHS GROUP INC History New 114,455 4,741 0.0% 50 +114,455 New Q4 2025 Mar 25, 2026
Integral Health Asset Management, LLC History New 100,000 4,143 0.21% 51 +100,000 New Q4 2025 Feb 17, 2026
AMERIPRISE FINANCIAL INC History New 96,688 4,005 0.0% 52 +96,688 New Q4 2025 Feb 17, 2026
Foresite Capital Management V, LLC History No change 86,291 3,575 2.17% 2.06% 53 0 0.0% Q4 2025 Feb 17, 2026
MPM BioImpact LLC History New 81,145 3,361 0.38% 54 +81,145 New Q4 2025 Feb 17, 2026
SPHERA FUNDS MANAGEMENT LTD. History Reduced 71,843 2,976 0.58% 0.84% 55 -82,500 -53.45% Q4 2025 Feb 17, 2026
SummitTX Capital, L.P. History New 69,560 2,881 0.09% 56 +69,560 New Q4 2025 Feb 17, 2026
RAYMOND JAMES FINANCIAL INC History New 67,718 2,805 0.0% 57 +67,718 New Q4 2025 Feb 18, 2026
WELLINGTON MANAGEMENT GROUP LLP History New 61,205 2,535 0.0% 58 +61,205 New Q4 2025 Feb 17, 2026
Bank of New York Mellon Corp History Added to 60,436 2,503 0.0% 0.0% 59 +15,196 33.59% Q4 2025 Feb 10, 2026
OSAIC HOLDINGS, INC. History Added to 59,762 2,475 0.0% 0.0% 60 +29,237 95.78% Q4 2025 Feb 17, 2026
Nuveen, LLC History Added to 57,258 2,372 0.0% 0.0% 61 +26,954 88.95% Q4 2025 Feb 12, 2026
FRANKLIN RESOURCES INC History Added to 55,229 2,288 0.0% 0.0% 62 +37,031 203.49% Q4 2025 Feb 11, 2026
Trexquant Investment LP History New 52,459 2,173 0.02% 63 +52,459 New Q4 2025 Feb 17, 2026
SEVEN GRAND MANAGERS, LLC History New 50,000 2,071 0.16% 64 +50,000 New Q4 2025 Feb 10, 2026
Schonfeld Strategic Advisors LLC History Reduced 48,200 1,996 0.01% 0.02% 65 -65,849 -57.74% Q4 2025 Feb 17, 2026
BARCLAYS PLC History Added to 39,508 1,636 0.0% 0.0% 66 +11,992 43.58% Q4 2025 Feb 13, 2026
D. E. Shaw & Co., Inc. History New 33,694 1,395 0.0% 67 +33,694 New Q4 2025 Feb 17, 2026
ALLIANCEBERNSTEIN L.P. History Reduced 33,220 1,376 0.0% 0.0% 68 -26,880 -44.73% Q4 2025 Feb 17, 2026
XTX Topco Ltd History Added to 33,021 1,368 0.04% 0.04% 69 +6,154 22.91% Q4 2025 Feb 17, 2026
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. History Added to 31,295 1,296 0.0% 0.0% 70 +22,217 244.73% Q4 2025 Feb 17, 2026
Cinctive Capital Management LP History New 29,134 1,207 0.07% 71 +29,134 New Q4 2025 Feb 17, 2026
UBS Group AG History Added to 28,698 1,188 0.0% 0.0% 72 +905 3.26% Q4 2025 Jan 29, 2026
AQR CAPITAL MANAGEMENT LLC History Reduced 27,439 1,136 0.0% 0.0% 73 -176 -0.64% Q4 2025 Feb 17, 2026
RENAISSANCE TECHNOLOGIES LLC History Reduced 27,100 1,122 0.0% 0.0% 74 -59,000 -68.52% Q4 2025 Feb 12, 2026
TUDOR INVESTMENT CORP ET AL History New 24,059 996 0.0% 75 +24,059 New Q4 2025 Feb 17, 2026
WELLS FARGO & COMPANY/MN History Added to 24,008 994 0.0% 0.0% 76 +9,229 62.45% Q4 2025 Feb 13, 2026
RHUMBLINE ADVISERS History Added to 23,731 983 0.0% 0.0% 77 +2,761 13.17% Q4 2025 Feb 13, 2026
GILDER GAGNON HOWE & CO LLC History New 23,282 964 0.01% 78 +23,282 New Q4 2025 Feb 17, 2026
Russell Investments Group, Ltd. History Added to 22,545 934 0.0% 0.0% 79 +20,638 1082.22% Q4 2025 Feb 17, 2026
Verition Fund Management LLC History New 22,512 932 0.0% 80 +22,512 New Q4 2025 Feb 13, 2026
AMERICAN CENTURY COMPANIES INC History New 21,509 891 0.0% 81 +21,509 New Q4 2025 Feb 13, 2026
ACUTA CAPITAL PARTNERS, LLC History New 20,000 828 0.56% 83 +20,000 New Q4 2025 Feb 17, 2026
JPMORGAN CHASE & CO History Added to 20,007 828 0.0% 0.0% 82 +12,117 153.57% Q4 2025 Feb 11, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History Added to 19,400 803 0.0% 0.0% 84 +3,235 20.01% Q4 2025 Feb 17, 2026
BANK OF AMERICA CORP /DE/ History Added to 18,381 761 0.0% 0.0% 85 +8,807 91.99% Q4 2025 Feb 17, 2026
DEUTSCHE BANK AG\ History Added to 15,522 643 0.0% 0.0% 86 +6,637 74.7% Q4 2025 Feb 11, 2026
LOS ANGELES CAPITAL MANAGEMENT LLC History New 19,100 634 0.0% 87 +19,100 New Q4 2025 Feb 11, 2026
TWO SIGMA ADVISERS, LP History New 14,800 613 0.0% 88 +14,800 New Q4 2025 Feb 17, 2026
PSP Research LLC History New 12,672 525 0.46% 89 +12,672 New Q4 2025 Feb 06, 2026
MetLife Investment Management, LLC History No change 11,801 488 0.0% 0.0% 90 0 0.0% Q4 2025 Feb 12, 2026
China Universal Asset Management Co., Ltd. History Added to 11,441 474 0.04% 0.0% 91 +9,441 472.05% Q4 2025 Jan 29, 2026
CITIGROUP INC History Added to 11,252 466 0.0% 0.0% 92 +10,983 4082.9% Q4 2025 Feb 13, 2026
STRS OHIO History Reduced 11,200 464 0.0% 0.0% 93 -6,700 -37.43% Q4 2025 Feb 02, 2026
Falcon Wealth Planning History New 10,030 415 0.03% 94 +10,030 New Q4 2025 Feb 03, 2026
PEAK6 LLC History New 9,200 381 0.0% 95 +9,200 New Q4 2025 Mar 12, 2026
SG Americas Securities, LLC History Added to 8,493 352 0.0% 0.0% 96 +3,478 69.35% Q4 2025 Jan 09, 2026
TWO SIGMA INVESTMENTS, LP History Reduced 7,245 300 0.0% 0.0% 97 -3,905 -35.02% Q4 2025 Feb 17, 2026
Caitong International Asset Management Co., Ltd History New 7,002 290 0.07% 98 +7,002 New Q4 2025 Mar 03, 2026
MANUFACTURERS LIFE INSURANCE COMPANY, THE History New 6,897 285 0.0% 99 +6,897 New Q4 2025 Feb 13, 2026
Virtus Investment Advisers, LLC History Reduced 6,846 283 0.08% 0.06% 100 -1,551 -18.47% Q4 2025 Feb 17, 2026
NEW YORK STATE COMMON RETIREMENT FUND History No change 6,700 277 0.0% 0.0% 101 0 0.0% Q4 2025 Feb 12, 2026
Persistent Asset Partners Ltd History New 6,605 273 0.12% 102 +6,605 New Q4 2025 Feb 17, 2026
INTECH INVESTMENT MANAGEMENT LLC History New 6,443 266 0.0% 103 +6,443 New Q4 2025 Feb 10, 2026
LANDSCAPE CAPITAL MANAGEMENT, L.L.C. History New 6,050 250 0.02% 105 +6,050 New Q4 2025 Feb 13, 2026
ProShare Advisors LLC History New 6,047 250 0.0% 104 +6,047 New Q4 2025 Feb 06, 2026
PROFUND ADVISORS LLC History New 6,016 249 0.01% 106 +6,016 New Q4 2025 Feb 06, 2026
Police & Firemen's Retirement System of New Jersey History Added to 5,961 246 0.0% 0.0% 107 +931 18.51% Q4 2025 Feb 13, 2026
SEI INVESTMENTS CO History New 5,668 234 0.0% 108 +5,668 New Q4 2025 Feb 13, 2026
BNP PARIBAS FINANCIAL MARKETS History Reduced 5,473 226 0.0% 0.0% 109 -6,545 -54.46% Q4 2025 Feb 10, 2026
CIBC Private Wealth Group LLC History New 5,400 223 0.0% 110 +5,400 New Q4 2025 Feb 12, 2026
Legal & General Group Plc History Added to 5,379 222 0.0% 0.0% 111 +160 3.07% Q4 2025 Feb 09, 2026
Rafferty Asset Management, LLC History New 5,244 217 0.0% 112 +5,244 New Q4 2025 Feb 13, 2026
Quantbot Technologies LP History New 5,221 216 0.01% 113 +5,221 New Q4 2025 Feb 10, 2026
WestHill Financial Advisors, Inc. History New 5,186 214 0.04% 114 +5,186 New Q4 2025 Jan 21, 2026
Brevan Howard Capital Management LP History New 5,042 208 0.0% 115 +5,042 New Q4 2025 Feb 17, 2026
IFP Advisors, Inc History New 3,514 145 0.0% 116 +3,514 New Q4 2025 Feb 06, 2026
Mirae Asset Global Investments Co., Ltd. History New 2,338 96 0.0% 117 +2,338 New Q4 2025 Jan 26, 2026
CWM, LLC History Added to 2,229 92 0.0% 0.0% 118 +91 4.26% Q4 2025 Jan 26, 2026
Ameritas Investment Partners, Inc. History No change 1,632 67 0.0% 0.0% 119 0 0.0% Q4 2025 Feb 11, 2026
Tower Research Capital LLC (TRC) History Reduced 1,349 55 0.0% 0.0% 120 -663 -32.95% Q4 2025 Feb 17, 2026
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM History Added to 1,321 54 0.0% 0.0% 121 +766 138.02% Q4 2025 Feb 17, 2026
Sterling Capital Management LLC History Reduced 1,161 48 0.0% 0.0% 122 -99 -7.86% Q4 2025 Feb 13, 2026
GF FUND MANAGEMENT CO. LTD. History New 944 39 0.0% 123 +944 New Q4 2025 Jan 27, 2026
AMALGAMATED BANK History Added to 674 28 0.0% 0.0% 124 +369 120.98% Q4 2025 Feb 05, 2026
ROYAL BANK OF CANADA History New 646 27 0.0% 125 +646 New Q4 2025 Feb 17, 2026
Farther Finance Advisors, LLC History Reduced 359 14 0.0% 0.0% 126 -24 -6.27% Q4 2025 Jan 23, 2026
NISA INVESTMENT ADVISORS, LLC History Added to 204 8 0.0% 127 +178 684.62% Q4 2025 Jan 15, 2026
Daiwa Securities Group Inc. History New 160 7 0.0% 128 +160 New Q4 2025 Feb 11, 2026
GAMMA Investing LLC History Added to 172 7 0.0% 0.0% 129 +13 8.18% Q4 2025 Jan 05, 2026
EverSource Wealth Advisors, LLC History No change 149 6 0.0% 0.0% 130 0 0.0% Q4 2025 Feb 06, 2026
Torren Management, LLC History New 112 4 0.0% 132 +112 New Q4 2025 Jan 30, 2026
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC History New 99 4 0.0% 131 +99 New Q4 2025 Feb 13, 2026
JONES FINANCIAL COMPANIES LLLP History New 90 3 0.0% 133 +90 New Q4 2025 Feb 17, 2026
SageView Advisory Group, LLC History New 54 2 0.0% 136 +54 New Q4 2025 Feb 17, 2026
PNC FINANCIAL SERVICES GROUP, INC. History Reduced 58 2 0.0% 0.0% 134 -35 -37.63% Q4 2025 Feb 06, 2026
SBI Securities Co., Ltd. History Added to 67 2 0.0% 0.0% 135 +6 9.84% Q4 2025 Feb 03, 2026
US BANCORP \DE\ History New 41 1 0.0% 137 +41 New Q4 2025 Jan 30, 2026
Cornerstone Financial Management LLC History New 28 1 0.0% 138 +28 New Q4 2025 Feb 13, 2026
Octagon Capital Advisors LP History Closed out 0 0 0.7% -177,667 -100.0% Q3 2025 Nov 14, 2025
Nantahala Capital Management, LLC History Closed out 0 0 0.08% -93,351 -100.0% Q3 2025 Nov 14, 2025
HARVARD MANAGEMENT CO INC History Closed out 0 0 0.11% -92,396 -100.0% Q3 2025 Nov 14, 2025
Caption Management, LLC History Closed out 0 0 0.01% -34,000 -100.0% Q3 2025 Nov 14, 2025
WINTON GROUP Ltd History Closed out 0 0 0.01% -14,487 -100.0% Q3 2025 Nov 13, 2025
ALPS ADVISORS INC History Closed out 0 0 0.0% -13,742 -100.0% Q3 2025 Nov 05, 2025
Arax Advisory Partners History Closed out 0 0 0.0% -307 -100.0% Q3 2025 Nov 14, 2025
SIGNATUREFD, LLC History New 14 0 +14 New Q4 2025 Jan 20, 2026
Rachor Investment Advisory Services, LLC History New 6 0 +6 New Q4 2025 Jan 30, 2026
Allworth Financial LP History New 5 0 +5 New Q4 2025 Feb 05, 2026
ROTHSCHILD INVESTMENT LLC History No change 10 0 0 0.0% Q4 2025 Feb 10, 2026
Sunbelt Securities, Inc. History No change 12 0 0 0.0% Q4 2025 Feb 20, 2026
True Wealth Design, LLC History No change 5 0 0 0.0% Q4 2025 Jan 08, 2026