Milestone Pharmaceuticals Inc. - MIST

Detailed investor-level table based on 13F positions.
Early Q1 2026 data: only 9 institutional holders reported so far. The full shareholder list will grow as more funds file with the SEC.

Shareholders (13F)

Quarter: Q4 2025 · Compare: Q3 2025
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
Propel Bio Management, LLC History Reduced 4,118,321 8,319 7.1% 10.26% 1 -1,006,569 -19.64% Q4 2025 Feb 11, 2026
ADAGE CAPITAL PARTNERS GP, L.L.C. History Reduced 2,810,037 5,676 0.01% 0.02% 2 -4,165,963 -59.72% Q4 2025 Feb 17, 2026
RTW INVESTMENTS, LP History New 2,506,102 5,062 0.05% 3 +2,506,102 New Q4 2025 Feb 17, 2026
MARSHALL WACE, LLP History Added to 1,656,821 3,346 0.0% 0.0% 4 +1,231,793 289.81% Q4 2025 Feb 13, 2026
TWO SIGMA INVESTMENTS, LP History Added to 1,514,461 3,059 0.0% 0.0% 5 +847,910 127.21% Q4 2025 Feb 17, 2026
Simplify Asset Management Inc. History Reduced 1,506,405 3,042 0.05% 0.1% 6 -1,326,569 -46.83% Q4 2025 Feb 09, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History Added to 1,249,400 2,523 0.0% 0.0% 7 +704,428 129.26% Q4 2025 Feb 17, 2026
JANE STREET GROUP, LLC History Added to 1,217,130 2,458 0.0% 0.0% 8 +795,938 188.97% Q4 2025 Feb 12, 2026
Pathstone Holdings, LLC History New 1,017,040 2,104 0.01% 9 +1,017,040 New Q4 2025 Feb 13, 2026
MORGAN STANLEY History Reduced 781,875 1,579 0.0% 0.0% 10 -2,187,192 -73.67% Q4 2025 Feb 13, 2026
Lion Point Capital, LP History Added to 755,000 1,525 7.89% 7.48% 11 +96,447 14.65% Q4 2025 Feb 17, 2026
TORONTO DOMINION BANK History No change 750,000 1,515 0.0% 0.0% 12 0 0.0% Q4 2025 Feb 17, 2026
Boxer Capital Management, LLC History No change 666,666 1,346 0.29% 0.42% 13 0 0.0% Q4 2025 Feb 17, 2026
Stonepine Capital Management, LLC History New 662,666 1,338 0.98% 14 +662,666 New Q4 2025 Feb 13, 2026
CITADEL ADVISORS LLC History Added to 637,232 1,287 0.0% 0.0% 15 +45,565 7.7% Q4 2025 Feb 17, 2026
TWO SIGMA ADVISERS, LP History Added to 619,592 1,251 0.0% 0.0% 16 +385,551 164.74% Q4 2025 Feb 17, 2026
GROUP ONE TRADING LLC History Added to 569,599 1,150 0.0% 0.0% 17 +547,577 2486.5% Q4 2025 Feb 12, 2026
UBS Group AG History Added to 491,868 993 0.0% 0.0% 18 +94,334 23.73% Q4 2025 Jan 29, 2026
Point72 Asset Management, L.P. History New 482,355 974 0.0% 19 +482,355 New Q4 2025 Feb 17, 2026
MILLENNIUM MANAGEMENT LLC History Added to 402,635 813 0.0% 0.0% 20 +1,076 0.27% Q4 2025 Feb 17, 2026
Aptus Capital Advisors, LLC History Added to 263,200 531 0.0% 0.0% 21 +53,000 25.21% Q4 2025 Feb 13, 2026
GUARDIAN WEALTH ADVISORS, LLC / NC History Added to 263,200 531 0.03% 0.03% 22 +53,000 25.21% Q4 2025 Feb 17, 2026
Squarepoint Ops LLC History New 249,344 503 0.0% 23 +249,344 New Q4 2025 Feb 13, 2026
GSA CAPITAL PARTNERS LLP History Added to 236,138 477 0.04% 0.01% 24 +157,391 199.87% Q4 2025 Feb 06, 2026
NOMURA HOLDINGS INC History New 225,000 454 0.0% 25 +225,000 New Q4 2025 Feb 17, 2026
BNP PARIBAS FINANCIAL MARKETS History New 221,951 448 0.0% 26 +221,951 New Q4 2025 Feb 10, 2026
ACADIAN ASSET MANAGEMENT LLC History New 176,200 353 0.0% 27 +176,200 New Q4 2025 Feb 10, 2026
XTX Topco Ltd History Reduced 171,960 347 0.01% 0.02% 28 -15,341 -8.19% Q4 2025 Feb 17, 2026
LPL Financial LLC History Added to 142,463 287 0.0% 0.0% 29 +47,163 49.49% Q4 2025 Feb 11, 2026
Graham Capital Management, L.P. History New 133,620 269 0.01% 30 +133,620 New Q4 2025 Feb 17, 2026
Valeo Financial Advisors, LLC History No change 130,699 264 0.01% 0.01% 31 0 0.0% Q4 2025 Feb 04, 2026
ADAR1 Capital Management, LLC History New 100,100 202 0.01% 33 +100,100 New Q4 2025 Feb 18, 2026
TRU INDEPENDENCE ASSET MANAGEMENT 2, LLC History New 100,000 202 0.13% 32 +100,000 New Q4 2025 Feb 24, 2026
SG Americas Securities, LLC History New 97,375 197 0.0% 34 +97,375 New Q4 2025 Jan 09, 2026
Cascades Capital Asset Management, LLC History Added to 77,510 156 0.07% 0.07% 35 +175 0.23% Q4 2025 Feb 04, 2026
GEODE CAPITAL MANAGEMENT, LLC History No change 74,022 149 0.0% 0.0% 36 0 0.0% Q4 2025 Feb 09, 2026
Engineers Gate Manager LP History New 59,053 119 0.0% 37 +59,053 New Q4 2025 Feb 17, 2026
October Effect Ltd History New 52,100 105 0.12% 38 +52,100 New Q4 2025 Jan 20, 2026
Cambridge Investment Research Advisors, Inc. History Added to 47,140 95 0.0% 0.0% 39 +34,442 271.24% Q4 2025 Feb 05, 2026
NORTHERN TRUST CORP History No change 39,258 79 0.0% 0.0% 40 0 0.0% Q4 2025 Feb 17, 2026
Focus Partners Wealth History No change 36,000 72 0.0% 0.0% 41 0 0.0% Q4 2025 Feb 13, 2026
Qube Research & Technologies Ltd History New 34,596 69 0.0% 42 +34,596 New Q4 2025 Feb 17, 2026
CITIGROUP INC History Added to 33,858 68 0.0% 0.0% 43 +26,046 333.41% Q4 2025 Feb 13, 2026
Scientech Research LLC History New 30,124 60 0.04% 44 +30,124 New Q4 2025 Feb 17, 2026
Federation des caisses Desjardins du Quebec History No change 29,781 60 0.0% 0.0% 45 0 0.0% Q4 2025 Feb 12, 2026
Bay Rivers Group History Added to 28,861 58 0.02% 0.01% 46 +12,170 72.91% Q4 2025 Jan 07, 2026
RAYMOND JAMES FINANCIAL INC History No change 26,600 53 0.0% 0.0% 47 0 0.0% Q4 2025 Feb 18, 2026
Mariner, LLC History No change 25,000 50 0.0% 0.0% 48 0 0.0% Q4 2025 Feb 13, 2026
Safeguard Investment Advisory Group, LLC History No change 25,044 50 0.01% 0.01% 49 0 0.0% Q4 2025 Feb 13, 2026
Creative Planning History No change 23,410 47 0.0% 0.0% 50 0 0.0% Q4 2025 Feb 17, 2026
Invesco Ltd. History New 21,893 44 0.0% 52 +21,893 New Q4 2025 Feb 19, 2026
STATE STREET CORP History Reduced 21,875 44 0.0% 0.0% 51 -345 -1.55% Q4 2025 Feb 13, 2026
Cetera Investment Advisers History New 20,722 41 0.0% 53 +20,722 New Q4 2025 Feb 17, 2026
JOURNEY STRATEGIC WEALTH LLC History Added to 30,000 40 0.0% 0.0% 54 +20,000 200.0% Q4 2025 Feb 13, 2026
Stephenson & Company, Inc. History No change 20,000 40 0.02% 0.02% 55 0 0.0% Q4 2025 Jan 27, 2026
Quantbot Technologies LP History New 18,990 38 0.0% 56 +18,990 New Q4 2025 Feb 10, 2026
NATIONAL BANK OF CANADA /FI/ History No change 18,700 37 0.0% 0.0% 57 0 0.0% Q4 2025 Feb 17, 2026
Bayesian Capital Management, LP History New 17,215 34 0.08% 58 +17,215 New Q4 2025 Feb 17, 2026
JONES FINANCIAL COMPANIES LLLP History Added to 16,000 32 0.0% 0.0% 59 +5,000 45.45% Q4 2025 Feb 17, 2026
SJS Investment Consulting Inc. History New 15,000 30 0.0% 60 +15,000 New Q4 2025 Jan 21, 2026
Beta Wealth Group, Inc. History No change 14,127 28 0.01% 0.01% 61 0 0.0% Q4 2025 Feb 13, 2026
Eaton Financial Holdings Company, LLC History New 12,750 25 0.01% 63 +12,750 New Q4 2025 Feb 09, 2026
Strategic Family Wealth Counselors, L.L.C. History New 12,675 25 0.01% 62 +12,675 New Q4 2025 Feb 04, 2026
Bronte Capital Management Pty Ltd. History New 10,414 21 0.0% 64 +10,414 New Q4 2025 Feb 03, 2026
INTEGRAL INVESTMENT ADVISORS, INC. History New 10,000 20 0.0% 68 +10,000 New Q4 2025 Feb 06, 2026
AQR CAPITAL MANAGEMENT LLC History No change 10,000 20 0.0% 0.0% 65 0 0.0% Q4 2025 Feb 17, 2026
Ancora Advisors LLC History No change 10,000 20 0.0% 0.0% 66 0 0.0% Q4 2025 Feb 17, 2026
Secure Asset Management, LLC History No change 10,000 20 0.0% 0.0% 67 0 0.0% Q4 2025 Jan 20, 2026
Taylor Financial Group, Inc. History No change 10,000 20 0.01% 0.01% 69 0 0.0% Q4 2025 Feb 06, 2026
Tower Research Capital LLC (TRC) History New 8,980 18 0.0% 70 +8,980 New Q4 2025 Feb 17, 2026
ROYAL BANK OF CANADA History New 6,698 13 0.0% 71 +6,698 New Q4 2025 Feb 17, 2026
US BANCORP \DE\ History No change 3,200 6 0.0% 0.0% 72 0 0.0% Q4 2025 Jan 30, 2026
Rockefeller Capital Management L.P. History New 1,700 3 0.0% 74 +1,700 New Q4 2025 Mar 16, 2026
Arax Advisory Partners History Added to 1,591 3 0.0% 0.0% 73 +514 47.73% Q4 2025 Feb 13, 2026
BANK OF AMERICA CORP /DE/ History Reduced 841 1 0.0% 0.0% 75 -15,211 -94.76% Q4 2025 Feb 17, 2026
ORBIMED ADVISORS LLC History Closed out 0 0 0.15% -3,221,828 -100.0% Q3 2025 Nov 14, 2025
SPHERA FUNDS MANAGEMENT LTD. History Closed out 0 0 0.35% -820,000 -100.0% Q3 2025 Nov 14, 2025
Affinity Asset Advisors, LLC History Closed out 0 0 0.12% -666,666 -100.0% Q3 2025 Nov 13, 2025
GOLDMAN SACHS GROUP INC History Closed out 0 0 0.0% -356,567 -100.0% Q3 2025 Nov 14, 2025
Quadrature Capital Ltd History Closed out 0 0 0.01% -223,470 -100.0% Q3 2025 Nov 13, 2025
HRT FINANCIAL LP History Closed out 0 0 0.0% -138,812 -100.0% Q3 2025 Nov 14, 2025
SIMPLEX TRADING, LLC History Closed out 0 0 0.0% -103,120 -100.0% Q3 2025 Nov 12, 2025
SAPIENT CAPITAL LLC History Closed out 0 0 0.0% -12,200 -100.0% Q3 2025 Oct 17, 2025
Wealthspire Advisors, LLC History Closed out 0 0 0.0% -1,129 -100.0% Q3 2025 Nov 14, 2025
Medallion Wealth Advisors, LLC History New 340 0 +340 New Q4 2025 Apr 24, 2026
Rialto Wealth Management, LLC History New 300 0 +300 New Q4 2025 Jan 12, 2026
Key Capital Management, INC History New 212 0 +212 New Q4 2025 Jan 26, 2026
SBI Securities Co., Ltd. History No change 6 0 0 0.0% Q4 2025 Feb 03, 2026