Orchestra BioMed Holdings, Inc. - OBIO

Detailed investor-level table based on 13F positions.

Shareholders (13F)

Quarter: Q1 2026 · Compare: Q4 2025
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
RTW INVESTMENTS, LP History No change 8,306,063 35,300 0.35% 0.35% 1 0 0.0% Q1 2026 May 15, 2026
PERCEPTIVE ADVISORS LLC History Reduced 5,037,906 21,411 0.42% 0.38% 2 -89,350 -1.74% Q1 2026 May 15, 2026
VANGUARD CAPITAL MANAGEMENT LLC History New 2,204,319 9,368 0.0% 3 +2,204,319 New Q1 2026 May 15, 2026
VANGUARD GROUP INC History No change 1,604,556 6,658 0.0% 0.0% 4 0 0.0% Q4 2025 Jan 29, 2026
Alyeska Investment Group, L.P. History No change 1,000,000 4,250 0.01% 0.01% 5 0 0.0% Q1 2026 May 15, 2026
Propel Bio Management, LLC History New 896,701 3,830 2.41% 6 +896,701 New Q1 2026 May 14, 2026
MILLENNIUM MANAGEMENT LLC History Added to 702,543 2,985 0.0% 0.0% 7 +459,070 188.55% Q1 2026 May 15, 2026
BlackRock, Inc. History Added to 635,714 2,701 0.0% 0.0% 8 +4,813 0.76% Q1 2026 May 13, 2026
GEODE CAPITAL MANAGEMENT, LLC History Added to 485,492 2,064 0.0% 0.0% 9 +12,129 2.56% Q1 2026 May 15, 2026
Affinity Asset Advisors, LLC History Reduced 402,550 1,710 0.09% 0.14% 10 -170,254 -29.72% Q1 2026 May 14, 2026
CHARLES SCHWAB INVESTMENT MANAGEMENT INC History Added to 265,499 1,128 0.0% 0.0% 11 +1,711 0.65% Q1 2026 May 15, 2026
Knott David M Jr History Added to 253,651 1,078 0.64% 0.48% 12 +3,651 1.46% Q1 2026 May 14, 2026
VANGUARD FIDUCIARY TRUST CO History New 235,214 999 0.0% 13 +235,214 New Q1 2026 May 08, 2026
Simplify Asset Management Inc. History New 219,387 932 0.01% 14 +219,387 New Q1 2026 Apr 27, 2026
MARSHALL WACE, LLP History Added to 188,484 801 0.0% 0.0% 15 +16,803 9.79% Q1 2026 May 14, 2026
683 Capital Management, LLC History Reduced 185,000 786 0.04% 0.04% 16 -19,076 -9.35% Q1 2026 May 15, 2026
STATE STREET CORP History Added to 169,410 719 0.0% 0.0% 17 +10,377 6.53% Q1 2026 May 15, 2026
GOLDMAN SACHS GROUP INC History Added to 155,242 659 0.0% 0.0% 18 +21,169 15.79% Q1 2026 May 15, 2026
DAFNA Capital Management LLC History No change 126,841 539 0.12% 0.12% 19 0 0.0% Q1 2026 May 15, 2026
NORTHERN TRUST CORP History Added to 118,274 502 0.0% 0.0% 20 +7,375 6.65% Q1 2026 May 14, 2026
Qube Research & Technologies Ltd History Added to 108,953 463 0.0% 0.0% 21 +2,211 2.07% Q1 2026 May 15, 2026
IFP Advisors, Inc History Added to 98,887 420 0.01% 0.01% 22 +12,189 14.06% Q1 2026 Apr 13, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History Reduced 97,521 414 0.0% 0.0% 23 -57,609 -37.14% Q1 2026 May 15, 2026
Point72 Asset Management, L.P. History Reduced 87,888 373 0.0% 0.0% 24 -74,058 -45.73% Q1 2026 May 15, 2026
CITADEL ADVISORS LLC History Added to 79,185 336 0.0% 0.0% 25 +8,210 11.57% Q1 2026 May 15, 2026
Hudson Bay Capital Management LP History Added to 71,134 302 0.0% 0.0% 26 +21,709 43.92% Q1 2026 May 13, 2026
JANE STREET GROUP, LLC History Reduced 70,980 301 0.0% 0.0% 28 -116,685 -62.18% Q1 2026 May 12, 2026
RENAISSANCE TECHNOLOGIES LLC History Reduced 70,900 301 0.0% 0.0% 27 -80,400 -53.14% Q1 2026 May 14, 2026
BRIDGEWAY CAPITAL MANAGEMENT, LLC History Added to 70,600 300 0.01% 0.0% 29 +45,600 182.4% Q1 2026 May 15, 2026
TWO SIGMA INVESTMENTS, LP History Reduced 60,107 255 0.0% 0.0% 30 -26,445 -30.55% Q1 2026 May 15, 2026
BARCLAYS PLC History Reduced 59,342 252 0.0% 0.0% 31 -35,175 -37.22% Q1 2026 May 14, 2026
Daytona Street Capital LLC History Added to 52,600 235 0.18% 0.07% 32 +31,100 144.65% Q1 2026 Apr 10, 2026
BANK OF AMERICA CORP /DE/ History Added to 52,761 224 0.0% 0.0% 33 +35,214 200.68% Q1 2026 May 15, 2026
Holos Integrated Wealth LLC History No change 51,595 219 0.11% 0.12% 34 0 0.0% Q1 2026 Apr 08, 2026
UBS Group AG History Added to 50,310 213 0.0% 0.0% 35 +38,921 341.74% Q1 2026 May 05, 2026
Brevan Howard Capital Management LP History New 36,769 156 0.0% 36 +36,769 New Q1 2026 May 15, 2026
MORGAN STANLEY History Reduced 35,639 151 0.0% 0.0% 37 -46,212 -56.46% Q1 2026 May 15, 2026
Meramec Financial Planners, LLC History No change 30,000 130 0.05% 0.05% 38 0 0.0% Q1 2026 Apr 27, 2026
Catalyst Funds Management Pty Ltd History New 27,644 117 0.02% 39 +27,644 New Q1 2026 May 11, 2026
TWO SIGMA ADVISERS, LP History No change 27,100 112 0.0% 0.0% 40 0 0.0% Q4 2025 Feb 17, 2026
CITIGROUP INC History Added to 25,529 108 0.0% 0.0% 41 +6,071 31.2% Q1 2026 May 11, 2026
Cannon Global Investment Management, LLC History New 22,607 96 0.19% 42 +22,607 New Q1 2026 Apr 21, 2026
RICE HALL JAMES & ASSOCIATES, LLC History New 19,001 80 0.0% 43 +19,001 New Q1 2026 May 15, 2026
Diametric Capital, LP History New 18,919 80 0.02% 44 +18,919 New Q1 2026 May 15, 2026
HighTower Advisors, LLC History No change 18,275 77 0.0% 0.0% 45 0 0.0% Q1 2026 May 05, 2026
FMR LLC History New 18,076 76 0.0% 46 +18,076 New Q1 2026 May 15, 2026
OMERS ADMINISTRATION Corp History Reduced 16,200 68 0.0% 0.0% 47 -50,900 -75.86% Q1 2026 May 15, 2026
ALGERT GLOBAL LLC History New 14,656 62 0.0% 48 +14,656 New Q1 2026 May 14, 2026
Vanguard Global Advisers, LLC History New 13,948 59 0.0% 49 +13,948 New Q1 2026 May 08, 2026
ABLE Financial Group, LLC History No change 13,402 56 0.01% 0.01% 50 0 0.0% Q1 2026 Apr 20, 2026
Frec Markets, Inc. History New 13,048 55 0.01% 51 +13,048 New Q1 2026 May 13, 2026
PRELUDE CAPITAL MANAGEMENT, LLC History New 12,389 52 0.0% 52 +12,389 New Q1 2026 May 15, 2026
CANADA PENSION PLAN INVESTMENT BOARD History Added to 11,300 48 0.0% 0.0% 53 +4,200 59.15% Q1 2026 May 15, 2026
Schonfeld Strategic Advisors LLC History New 10,953 46 0.0% 54 +10,953 New Q1 2026 May 15, 2026
Garden State Investment Advisory Services LLC History New 10,562 44 0.01% 56 +10,562 New Q1 2026 May 13, 2026
NewEdge Advisors, LLC History No change 44,083 44 0.0% 0.0% 55 0 0.0% Q1 2026 May 15, 2026
China Universal Asset Management Co., Ltd. History Added to 10,020 42 0.0% 0.0% 57 +819 8.9% Q1 2026 Apr 27, 2026
JPMORGAN CHASE & CO History Reduced 4,258 17 0.0% 0.0% 58 -328 -7.15% Q1 2026 May 13, 2026
Mirae Asset Global Investments Co., Ltd. History Added to 2,945 12 0.0% 0.0% 59 +201 7.33% Q1 2026 May 04, 2026
SIMPLEX TRADING, LLC History Reduced 2,381 10 0.0% 0.0% 60 -21,919 -90.2% Q1 2026 May 14, 2026
AdvisorNet Financial, Inc History New 1,696 7 0.0% 61 +1,696 New Q1 2026 Apr 17, 2026
BNP PARIBAS FINANCIAL MARKETS History Reduced 1,456 6 0.0% 0.0% 62 -15,551 -91.44% Q1 2026 May 12, 2026
GF FUND MANAGEMENT CO. LTD. History Added to 1,260 5 0.0% 0.0% 63 +151 13.62% Q1 2026 Apr 15, 2026
ROYAL BANK OF CANADA History Added to 936 4 0.0% 0.0% 64 +565 152.29% Q1 2026 May 15, 2026
GROUP ONE TRADING LLC History Reduced 700 2 0.0% 0.0% 65 -16,200 -95.86% Q1 2026 May 13, 2026
Tower Research Capital LLC (TRC) History Reduced 547 2 0.0% 0.0% 66 -99 -15.33% Q1 2026 May 15, 2026
JONES FINANCIAL COMPANIES LLLP History New 388 1 0.0% 67 +388 New Q1 2026 May 15, 2026
PRICE T ROWE ASSOCIATES INC /MD/ History Closed out 0 0 0.0% -364,645 -100.0% Q1 2026 May 15, 2026
ExodusPoint Capital Management, LP History Closed out 0 0 0.0% -95,635 -100.0% Q1 2026 May 14, 2026
XTX Topco Ltd History Closed out 0 0 0.01% -50,358 -100.0% Q1 2026 May 15, 2026
TD ASSET MANAGEMENT INC History Closed out 0 0 0.0% -45,692 -100.0% Q1 2026 May 11, 2026
Squarepoint Ops LLC History Closed out 0 0 0.0% -44,343 -100.0% Q1 2026 May 15, 2026
MANUFACTURERS LIFE INSURANCE COMPANY, THE History Closed out 0 0 0.0% -32,518 -100.0% Q1 2026 May 15, 2026
Lighthouse Investment Partners, LLC History Closed out 0 0 0.0% -24,900 -100.0% Q1 2026 May 14, 2026
Cresset Asset Management, LLC History Closed out 0 0 0.0% -20,000 -100.0% Q1 2026 May 15, 2026
BALYASNY ASSET MANAGEMENT L.P. History Closed out 0 0 0.0% -18,268 -100.0% Q1 2026 May 15, 2026
AQR CAPITAL MANAGEMENT LLC History Closed out 0 0 0.0% -16,290 -100.0% Q1 2026 May 15, 2026
Creative Planning History Closed out 0 0 0.0% -16,290 -100.0% Q1 2026 May 12, 2026
Virtu Financial LLC History Closed out 0 0 0.0% -13,623 -100.0% Q1 2026 May 14, 2026
GSA CAPITAL PARTNERS LLP History Closed out 0 0 0.0% -10,773 -100.0% Q1 2026 May 08, 2026
HARBOUR INVESTMENTS, INC. History Closed out 0 0 0.0% -1,988 -100.0% Q1 2026 May 15, 2026
Optiver Holding B.V. History Closed out 0 0 0.0% -312 -100.0% Q1 2026 May 15, 2026
SBI Securities Co., Ltd. History No change 6 0 0 0.0% Q1 2026 Apr 27, 2026