Prelude Therapeutics Inc - PRLD

Detailed investor-level table based on 13F positions.

Shareholders (13F)

Quarter: Q1 2026 · Compare: Q4 2025
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
ORBIMED ADVISORS LLC History No change 10,909,256 37,309 0.74% 0.65% 1 0 0.0% Q1 2026 May 15, 2026
BAKER BROS. ADVISORS LP History No change 10,123,824 34,623 0.2% 0.17% 2 0 0.0% Q1 2026 May 15, 2026
Kynam Capital Management, LP History Added to 1,592,551 5,446 0.34% 0.15% 3 +803,684 101.88% Q1 2026 May 15, 2026
VANGUARD CAPITAL MANAGEMENT LLC History New 1,230,406 4,207 0.0% 4 +1,230,406 New Q1 2026 May 15, 2026
VANGUARD GROUP INC History No change 1,413,986 4,100 0.0% 0.0% 5 0 0.0% Q4 2025 Jan 29, 2026
EcoR1 Capital, LLC History New 947,049 3,238 0.14% 6 +947,049 New Q1 2026 May 15, 2026
TWO SIGMA INVESTMENTS, LP History Added to 923,626 3,158 0.0% 0.0% 7 +134,931 17.11% Q1 2026 May 15, 2026
SPHERA FUNDS MANAGEMENT LTD. History Added to 558,339 1,909 0.3% 0.07% 8 +435,587 354.85% Q1 2026 May 15, 2026
ACADIAN ASSET MANAGEMENT LLC History Reduced 511,519 1,747 0.0% 0.0% 9 -24,184 -4.51% Q1 2026 May 13, 2026
MILLENNIUM MANAGEMENT LLC History Added to 382,737 1,308 0.0% 0.0% 10 +231,740 153.47% Q1 2026 May 15, 2026
MARSHALL WACE, LLP History Added to 358,906 1,227 0.0% 0.0% 11 +85,023 31.04% Q1 2026 May 14, 2026
MORGAN STANLEY History Reduced 322,161 1,101 0.0% 0.0% 12 -12,755 -3.81% Q1 2026 May 15, 2026
BlackRock, Inc. History Added to 321,886 1,100 0.0% 0.0% 13 +55,606 20.88% Q1 2026 May 13, 2026
GEODE CAPITAL MANAGEMENT, LLC History Added to 302,458 1,034 0.0% 0.0% 14 +29,572 10.84% Q1 2026 May 15, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History Added to 288,788 987 0.0% 0.0% 15 +120,379 71.48% Q1 2026 May 15, 2026
RENAISSANCE TECHNOLOGIES LLC History Added to 275,200 941 0.0% 0.0% 16 +3,900 1.44% Q1 2026 May 14, 2026
GOLDMAN SACHS GROUP INC History Added to 236,469 808 0.0% 0.0% 17 +118,992 101.29% Q1 2026 May 15, 2026
TWO SIGMA ADVISERS, LP History No change 237,300 688 0.0% 0.0% 18 0 0.0% Q4 2025 Feb 17, 2026
JANE STREET GROUP, LLC History Added to 192,963 659 0.0% 0.0% 19 +81,923 73.78% Q1 2026 May 12, 2026
VANGUARD FIDUCIARY TRUST CO History New 157,380 538 0.0% 20 +157,380 New Q1 2026 May 08, 2026
ADAR1 Capital Management, LLC History New 152,825 522 0.03% 21 +152,825 New Q1 2026 May 15, 2026
STATE STREET CORP History Added to 138,231 472 0.0% 0.0% 22 +10,939 8.59% Q1 2026 May 15, 2026
CITADEL ADVISORS LLC History New 124,378 425 0.0% 23 +124,378 New Q1 2026 May 15, 2026
Connor, Clark & Lunn Investment Management Ltd. History Added to 109,085 373 0.0% 0.0% 24 +62,995 136.68% Q1 2026 May 11, 2026
UBS Group AG History Added to 64,505 220 0.0% 0.0% 25 +62,648 3373.61% Q1 2026 May 05, 2026
HRT FINANCIAL LP History New 58,699 200 0.0% 26 +58,699 New Q1 2026 May 14, 2026
XTX Topco Ltd History Added to 57,190 195 0.0% 0.0% 27 +7,031 14.02% Q1 2026 May 15, 2026
BANK OF AMERICA CORP /DE/ History Added to 56,525 193 0.0% 0.0% 28 +46,717 476.32% Q1 2026 May 15, 2026
BRIDGEWAY CAPITAL MANAGEMENT, LLC History No change 53,500 182 0.0% 0.0% 29 0 0.0% Q1 2026 May 15, 2026
NORTHERN TRUST CORP History No change 50,120 171 0.0% 0.0% 30 0 0.0% Q1 2026 May 14, 2026
Focus Partners Wealth History No change 50,007 171 0.0% 0.0% 31 0 0.0% Q1 2026 May 14, 2026
DIMENSIONAL FUND ADVISORS LP History New 35,210 119 0.0% 32 +35,210 New Q1 2026 May 07, 2026
Cerity Partners LLC History Reduced 32,875 112 0.0% 0.0% 33 -78 -0.24% Q1 2026 May 15, 2026
OMERS ADMINISTRATION Corp History Reduced 32,700 111 0.0% 0.0% 34 -40,300 -55.21% Q1 2026 May 15, 2026
PRUDENTIAL FINANCIAL INC History Added to 17,420 59 0.0% 0.0% 35 +1,900 12.24% Q1 2026 May 13, 2026
Qube Research & Technologies Ltd History Reduced 16,417 56 0.0% 0.0% 36 -5,134 -23.82% Q1 2026 May 15, 2026
Point72 Asset Management, L.P. History Reduced 16,329 55 0.0% 0.0% 37 -42,839 -72.4% Q1 2026 May 15, 2026
HSBC HOLDINGS PLC History No change 13,652 47 0.0% 0.0% 38 0 0.0% Q1 2026 Apr 30, 2026
Diametric Capital, LP History New 11,980 40 0.01% 40 +11,980 New Q1 2026 May 15, 2026
NINE MASTS CAPITAL Ltd History New 11,699 40 0.01% 39 +11,699 New Q1 2026 May 12, 2026
Graham Capital Management, L.P. History New 11,343 38 0.0% 41 +11,343 New Q1 2026 May 15, 2026
AMERICAN CENTURY COMPANIES INC History New 10,294 35 0.0% 42 +10,294 New Q1 2026 May 15, 2026
BARCLAYS PLC History Reduced 8,600 29 0.0% 0.0% 43 -2 -0.02% Q1 2026 May 14, 2026
FMR LLC History Reduced 6,009 20 0.0% 0.0% 44 -143 -2.32% Q1 2026 May 15, 2026
Vanguard Global Advisers, LLC History New 4,636 15 0.0% 45 +4,636 New Q1 2026 May 08, 2026
GROUP ONE TRADING LLC History Added to 3,907 13 0.0% 0.0% 46 +3,407 681.4% Q1 2026 May 13, 2026
SBI Securities Co., Ltd. History Reduced 2,641 9 0.0% 0.0% 47 -100 -3.65% Q1 2026 Apr 27, 2026
ROYAL BANK OF CANADA History Added to 2,331 8 0.0% 0.0% 48 +589 33.81% Q1 2026 May 15, 2026
NISA INVESTMENT ADVISORS, LLC History No change 1,634 5 0.0% 0.0% 49 0 0.0% Q1 2026 Apr 30, 2026
PNC FINANCIAL SERVICES GROUP, INC. History No change 1,171 4 0.0% 0.0% 50 0 0.0% Q1 2026 May 08, 2026
CALDWELL SUTTER CAPITAL, INC. History Reduced 1,000 3 0.0% 0.0% 51 -1,000 -50.0% Q1 2026 May 05, 2026
CWM, LLC History Reduced 573 1 0.0% 0.0% 52 -119 -17.2% Q1 2026 May 14, 2026
PRICE T ROWE ASSOCIATES INC /MD/ History Closed out 0 0 0.0% -755,956 -100.0% Q1 2026 May 15, 2026
TD ASSET MANAGEMENT INC History Closed out 0 0 0.0% -160,652 -100.0% Q1 2026 May 11, 2026
MANUFACTURERS LIFE INSURANCE COMPANY, THE History Closed out 0 0 0.0% -70,546 -100.0% Q1 2026 May 15, 2026
Fortitude Family Office, LLC History New 230 0 +230 New Q1 2026 Apr 15, 2026
CITIGROUP INC History Added to 5 0 +4 400.0% Q1 2026 May 11, 2026
IFP Advisors, Inc History Closed out 0 0 -1 -100.0% Q1 2026 Apr 13, 2026
JPMORGAN CHASE & CO History No change 62 0 0 0.0% Q1 2026 May 13, 2026
BNP PARIBAS FINANCIAL MARKETS History No change 95 0 0 0.0% Q1 2026 May 12, 2026
Optiver Holding B.V. History No change 20 0 0 0.0% Q1 2026 Jun 02, 2026