Prelude Therapeutics Inc - PRLD

Detailed investor-level table based on 13F positions.

Shareholders (13F)

Quarter: Q2 2026 · Compare: Q1 2026
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
ORBIMED ADVISORS LLC History Added to 13,724,571 73,151 1.36% 0.74% 1 +2,815,315 25.81% Q2 2026 Aug 14, 2026
BAKER BROS. ADVISORS LP History No change 10,123,824 53,959 0.27% 0.2% 2 0 0.0% Q2 2026 Aug 14, 2026
RA CAPITAL MANAGEMENT, L.P. History New 6,475,882 34,516 0.3% — 3 +6,475,882 New Q2 2026 Aug 14, 2026
Soleus Capital Management, L.P. History New 3,378,378 18,006 0.62% — 4 +3,378,378 New Q2 2026 Aug 11, 2026
Kynam Capital Management, LP History Added to 2,415,087 12,872 0.71% 0.34% 5 +822,536 51.65% Q2 2026 Aug 14, 2026
VANGUARD CAPITAL MANAGEMENT LLC History Added to 2,009,445 10,710 0.0% 0.0% 6 +779,039 63.32% Q2 2026 Aug 13, 2026
BlackRock, Inc. History Added to 1,797,501 9,580 0.0% 0.0% 7 +1,475,615 458.43% Q2 2026 Aug 07, 2026
SPHERA FUNDS MANAGEMENT LTD. History Added to 1,019,832 5,435 0.71% 0.3% 8 +461,493 82.65% Q2 2026 Aug 14, 2026
TWO SIGMA INVESTMENTS, LP History Added to 993,369 5,294 0.0% 0.0% 9 +69,743 7.55% Q2 2026 Aug 14, 2026
ADAR1 Capital Management, LLC History Added to 900,900 4,801 0.22% 0.03% 10 +748,075 489.5% Q2 2026 Aug 14, 2026
MILLENNIUM MANAGEMENT LLC History Added to 844,993 4,503 0.0% 0.0% 11 +462,256 120.78% Q2 2026 Aug 14, 2026
GEODE CAPITAL MANAGEMENT, LLC History Added to 841,862 4,487 0.0% 0.0% 12 +539,404 178.34% Q2 2026 Aug 12, 2026
ADAGE CAPITAL PARTNERS GP, L.L.C. History New 766,095 4,083 0.01% — 13 +766,095 New Q2 2026 Aug 14, 2026
ACADIAN ASSET MANAGEMENT LLC History Added to 611,359 3,253 0.0% 0.0% 14 +99,840 19.52% Q2 2026 Aug 13, 2026
MORGAN STANLEY History Added to 503,860 2,685 0.0% 0.0% 15 +181,699 56.4% Q2 2026 Aug 13, 2026
STATE STREET CORP History Added to 428,787 2,285 0.0% 0.0% 16 +290,556 210.2% Q2 2026 Sep 22, 2026
UBS Group AG History Added to 318,797 1,699 0.0% 0.0% 17 +254,292 394.22% Q2 2026 Aug 13, 2026
VANGUARD FIDUCIARY TRUST CO History Added to 284,886 1,518 0.0% 0.0% 18 +127,506 81.02% Q2 2026 Aug 13, 2026
RENAISSANCE TECHNOLOGIES LLC History Added to 281,200 1,498 0.0% 0.0% 19 +6,000 2.18% Q2 2026 Aug 13, 2026
NORTHERN TRUST CORP History Added to 240,599 1,282 0.0% 0.0% 20 +190,479 380.05% Q2 2026 Aug 13, 2026
VANGUARD PORTFOLIO MANAGEMENT LLC History New 193,920 1,033 0.0% — 21 +193,920 New Q2 2026 Aug 13, 2026
MARSHALL WACE, LLP History Reduced 190,692 1,016 0.0% 0.0% 22 -168,214 -46.87% Q2 2026 Aug 13, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History Reduced 174,700 931 0.0% 0.0% 23 -114,088 -39.51% Q2 2026 Aug 14, 2026
Connor, Clark & Lunn Investment Management Ltd. History Added to 125,606 669 0.0% 0.0% 24 +16,521 15.15% Q2 2026 Aug 12, 2026
GOLDMAN SACHS GROUP INC History Reduced 120,834 644 0.0% 0.0% 25 -115,635 -48.9% Q2 2026 Aug 14, 2026
JANE STREET GROUP, LLC History Reduced 84,200 448 0.0% 0.0% 26 -108,763 -56.36% Q2 2026 Aug 14, 2026
Hillsdale Investment Management Inc. History New 81,400 433 0.01% — 27 +81,400 New Q2 2026 Aug 12, 2026
CITADEL ADVISORS LLC History Reduced 69,954 372 0.0% 0.0% 28 -54,424 -43.76% Q2 2026 Sep 02, 2026
Bank of New York Mellon Corp History New 68,187 363 0.0% — 29 +68,187 New Q2 2026 Aug 06, 2026
CHARLES SCHWAB INVESTMENT MANAGEMENT INC History New 67,622 360 0.0% — 30 +67,622 New Q2 2026 Aug 14, 2026
BRIDGEWAY CAPITAL MANAGEMENT, LLC History Added to 64,500 343 0.01% 0.0% 31 +11,000 20.56% Q2 2026 Aug 14, 2026
Squarepoint Ops LLC History New 59,540 317 0.0% — 32 +59,540 New Q2 2026 Aug 14, 2026
PANAGORA ASSET MANAGEMENT INC History New 47,574 253 0.0% — 33 +47,574 New Q2 2026 Aug 06, 2026
Mariner, LLC History New 45,261 241 0.0% — 34 +45,261 New Q2 2026 Aug 13, 2026
Nuveen, LLC History New 37,023 197 0.0% — 35 +37,023 New Q2 2026 Aug 11, 2026
DIMENSIONAL FUND ADVISORS LP History No change 35,210 186 0.0% 0.0% 36 0 0.0% Q2 2026 Aug 11, 2026
Invesco Ltd. History New 34,742 185 0.0% — 37 +34,742 New Q2 2026 Aug 14, 2026
State of Wyoming History New 32,862 175 0.02% — 39 +32,862 New Q2 2026 Aug 06, 2026
Cerity Partners LLC History No change 32,875 175 0.0% 0.0% 38 0 0.0% Q2 2026 Aug 14, 2026
Graham Capital Management, L.P. History Added to 29,770 158 0.0% 0.0% 40 +18,427 162.45% Q2 2026 Aug 14, 2026
DEUTSCHE BANK AG\ History New 27,824 148 0.0% — 41 +27,824 New Q2 2026 Aug 07, 2026
WELLS FARGO & COMPANY/MN History New 25,325 134 0.0% — 42 +25,325 New Q2 2026 Aug 14, 2026
BANK OF AMERICA CORP /DE/ History Reduced 23,875 127 0.0% 0.0% 43 -32,650 -57.76% Q2 2026 Aug 14, 2026
PRICE T ROWE ASSOCIATES INC /MD/ History New 22,758 122 0.0% — 44 +22,758 New Q2 2026 Aug 14, 2026
RHUMBLINE ADVISERS History New 22,074 117 0.0% — 45 +22,074 New Q2 2026 Aug 11, 2026
Vanguard Global Advisers, LLC History Added to 16,210 86 0.0% 0.0% 46 +11,574 249.65% Q2 2026 Aug 13, 2026
ExodusPoint Capital Management, LP History New 15,475 82 0.0% — 47 +15,475 New Q2 2026 Aug 14, 2026
BARCLAYS PLC History Added to 14,529 77 0.0% 0.0% 48 +5,929 68.94% Q2 2026 Aug 14, 2026
NEW YORK STATE COMMON RETIREMENT FUND History New 14,200 75 0.0% — 49 +14,200 New Q2 2026 Jul 29, 2026
HSBC HOLDINGS PLC History No change 13,652 74 0.0% 0.0% 50 0 0.0% Q2 2026 Aug 14, 2026
MANGROVE PARTNERS IM, LLC History New 13,352 71 0.0% — 51 +13,352 New Q2 2026 Aug 14, 2026
CITIGROUP INC History Added to 13,033 69 0.0% — 52 +13,028 260560.0% Q2 2026 Aug 03, 2026
Qube Research & Technologies Ltd History Reduced 13,110 69 0.0% 0.0% 53 -3,307 -20.14% Q2 2026 Aug 14, 2026
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. History New 12,784 68 0.0% — 55 +12,784 New Q2 2026 Aug 14, 2026
GSA CAPITAL PARTNERS LLP History New 12,672 68 0.0% — 54 +12,672 New Q2 2026 Aug 06, 2026
JPMORGAN CHASE & CO History Added to 13,538 66 0.0% — 56 +13,476 21735.48% Q2 2026 Aug 12, 2026
Spark Investment Management LLC History New 10,600 56 0.11% — 57 +10,600 New Q2 2026 Aug 10, 2026
Police & Firemen's Retirement System of New Jersey History New 10,492 55 0.0% — 58 +10,492 New Q2 2026 Jul 23, 2026
ALLIANCEBERNSTEIN L.P. History New 10,530 36 0.0% — 59 +10,530 New Q2 2026 Aug 14, 2026
LOS ANGELES CAPITAL MANAGEMENT LLC History New 6,430 34 0.0% — 60 +6,430 New Q2 2026 Aug 13, 2026
FMR LLC History Reduced 5,629 30 0.0% 0.0% 61 -380 -6.32% Q2 2026 Aug 13, 2026
STRS OHIO History New 5,500 29 0.0% — 62 +5,500 New Q2 2026 Jul 30, 2026
BNP PARIBAS FINANCIAL MARKETS History Added to 4,104 21 0.0% — 63 +4,009 4220.0% Q2 2026 Aug 13, 2026
GROUP ONE TRADING LLC History No change 3,907 20 0.0% 0.0% 64 0 0.0% Q2 2026 Aug 13, 2026
Legal & General Group Plc History New 2,699 14 0.0% — 66 +2,699 New Q2 2026 Aug 14, 2026
ROYAL BANK OF CANADA History Added to 2,658 14 0.0% 0.0% 65 +327 14.03% Q2 2026 Aug 14, 2026
Ameritas Investment Partners, Inc. History New 2,520 13 0.0% — 67 +2,520 New Q2 2026 Aug 13, 2026
Tower Research Capital LLC (TRC) History New 2,377 12 0.0% — 68 +2,377 New Q2 2026 Aug 11, 2026
Russell Investments Group, Ltd. History New 2,220 11 0.0% — 69 +2,220 New Q2 2026 Aug 06, 2026
NISA INVESTMENT ADVISORS, LLC History No change 1,634 8 0.0% 0.0% 70 0 0.0% Q2 2026 Aug 10, 2026
PNC FINANCIAL SERVICES GROUP, INC. History No change 1,171 6 0.0% 0.0% 71 0 0.0% Q2 2026 Aug 07, 2026
Quarry LP History New 755 4 0.0% — 72 +755 New Q2 2026 Aug 14, 2026
CWM, LLC History No change 573 1 0.0% 0.0% 73 0 0.0% Q1 2026 May 14, 2026
Fortitude Family Office, LLC History No change 230 1 0.0% — 74 0 0.0% Q2 2026 Jul 20, 2026
EcoR1 Capital, LLC History Closed out 0 0 — 0.14% — -947,049 -100.0% Q2 2026 Aug 14, 2026
HRT FINANCIAL LP History Closed out 0 0 — 0.0% — -58,699 -100.0% Q2 2026 Aug 14, 2026
XTX Topco Ltd History Closed out 0 0 — 0.0% — -57,190 -100.0% Q2 2026 Aug 14, 2026
Focus Partners Wealth History Closed out 0 0 — 0.0% — -50,007 -100.0% Q2 2026 Aug 12, 2026
OMERS ADMINISTRATION Corp History Closed out 0 0 — 0.0% — -32,700 -100.0% Q2 2026 Aug 13, 2026
PRUDENTIAL FINANCIAL INC History Closed out 0 0 — 0.0% — -17,420 -100.0% Q2 2026 Aug 12, 2026
Point72 Asset Management, L.P. History Closed out 0 0 — 0.0% — -16,329 -100.0% Q2 2026 Aug 14, 2026
Diametric Capital, LP History Closed out 0 0 — 0.01% — -11,980 -100.0% Q2 2026 Aug 14, 2026
NINE MASTS CAPITAL Ltd History Closed out 0 0 — 0.01% — -11,699 -100.0% Q2 2026 Aug 07, 2026
AMERICAN CENTURY COMPANIES INC History Closed out 0 0 — 0.0% — -10,294 -100.0% Q2 2026 Aug 12, 2026
SBI Securities Co., Ltd. History Reduced 22 0 — 0.0% — -2,619 -99.17% Q2 2026 Jul 22, 2026
CALDWELL SUTTER CAPITAL, INC. History Closed out 0 0 — 0.0% — -1,000 -100.0% Q2 2026 Aug 05, 2026
Sterling Capital Management LLC History New 97 0 — — — +97 New Q2 2026 Jul 28, 2026
Caitong International Asset Management Co., Ltd History New 18 0 — — — +18 New Q2 2026 Aug 04, 2026
Optiver Holding B.V. History Reduced 4 0 — — — -16 -80.0% Q2 2026 Aug 12, 2026