ProQR Therapeutics N.V. - PRQR

Detailed investor-level table based on 13F positions.
Early Q1 2026 data: only 7 institutional holders reported so far. The full shareholder list will grow as more funds file with the SEC.

Shareholders (13F)

Quarter: Q4 2025 · Compare: Q3 2025
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
ADAGE CAPITAL PARTNERS GP, L.L.C. History No change 6,253,467 12,632 0.02% 0.02% 1 0 0.0% Q4 2025 Feb 17, 2026
Privium Fund Management B.V. History Added to 5,357,762 10,822 1.99% 1.91% 2 +359,475 7.19% Q4 2025 Feb 03, 2026
Aberdeen Group plc History Added to 2,950,676 5,960 0.01% 0.01% 3 +651,853 28.36% Q4 2025 Jan 16, 2026
Affinity Asset Advisors, LLC History Reduced 2,454,278 4,957 0.28% 0.67% 4 -1,145,722 -31.83% Q4 2025 Feb 13, 2026
Sio Capital Management, LLC History Added to 2,164,181 4,371 0.69% 1.12% 5 +89,042 4.29% Q4 2025 Feb 17, 2026
DAFNA Capital Management LLC History No change 1,567,561 3,166 0.74% 0.82% 6 0 0.0% Q4 2025 Feb 17, 2026
Kynam Capital Management, LP History Reduced 1,566,317 3,163 0.2% 0.26% 7 -83,145 -5.04% Q4 2025 Feb 17, 2026
Ikarian Capital, LLC History Added to 1,492,229 3,014 0.24% 0.19% 8 +600,000 67.25% Q4 2025 Feb 18, 2026
MORGAN STANLEY History Reduced 1,367,119 2,761 0.0% 0.0% 9 -1,534,083 -52.88% Q4 2025 Feb 13, 2026
PLATINUM INVESTMENT MANAGEMENT LTD History No change 1,235,514 2,495 0.58% 0.17% 10 0 0.0% Q4 2025 Feb 13, 2026
ArrowMark Colorado Holdings LLC History Reduced 1,164,722 2,352 0.05% 0.05% 11 -81,512 -6.54% Q4 2025 Feb 17, 2026
M28 Capital Management LP History No change 1,019,498 2,059 1.5% 3.19% 12 0 0.0% Q4 2025 Feb 13, 2026
TWO SIGMA INVESTMENTS, LP History Added to 839,384 1,695 0.0% 0.0% 13 +422,084 101.15% Q4 2025 Feb 17, 2026
Point72 Asset Management, L.P. History Added to 813,650 1,643 0.0% 0.0% 14 +63,650 8.49% Q4 2025 Feb 17, 2026
UBS Group AG History Added to 797,664 1,611 0.0% 0.0% 15 +703,114 743.64% Q4 2025 Jan 29, 2026
NOMURA ASSET MANAGEMENT INTERNATIONAL INC. History New 620,000 1,252 0.0% 16 +620,000 New Q4 2025 Feb 17, 2026
CITADEL ADVISORS LLC History Reduced 617,422 1,247 0.0% 0.0% 17 -39,590 -6.03% Q4 2025 Feb 17, 2026
Walleye Capital LLC History Added to 591,785 1,195 0.0% 0.0% 18 +59,808 11.24% Q4 2025 Feb 13, 2026
TWO SIGMA ADVISERS, LP History Added to 452,400 913 0.0% 0.0% 19 +223,800 97.9% Q4 2025 Feb 17, 2026
MILLENNIUM MANAGEMENT LLC History Added to 434,991 878 0.0% 0.0% 20 +194,369 80.78% Q4 2025 Feb 17, 2026
Monaco Asset Management SAM History Reduced 428,803 866 0.15% 0.06% 21 -31,197 -6.78% Q4 2025 Feb 10, 2026
BOOTHBAY FUND MANAGEMENT, LLC History Added to 355,283 717 0.01% 0.01% 22 +106,993 43.09% Q4 2025 Feb 17, 2026
RAYMOND JAMES FINANCIAL INC History Added to 342,886 692 0.0% 0.0% 23 +232,616 210.95% Q4 2025 Feb 18, 2026
NORTHERN TRUST CORP History No change 294,742 595 0.0% 0.0% 24 0 0.0% Q4 2025 Feb 17, 2026
Palo Alto Investors LP History No change 188,807 381 0.05% 0.07% 25 0 0.0% Q4 2025 Feb 17, 2026
BANK OF AMERICA CORP /DE/ History Added to 173,924 351 0.0% 0.0% 26 +54,726 45.91% Q4 2025 Feb 17, 2026
DIADEMA PARTNERS LP History Added to 167,532 338 0.06% 0.09% 27 +9,838 6.24% Q4 2025 Feb 17, 2026
JANE STREET GROUP, LLC History Added to 160,175 323 0.0% 0.0% 28 +149,414 1388.48% Q4 2025 Feb 12, 2026
BNP PARIBAS FINANCIAL MARKETS History Added to 157,149 317 0.0% 0.0% 29 +17,555 12.58% Q4 2025 Feb 10, 2026
FRANKLIN STREET ADVISORS INC /NC History No change 150,000 303 0.02% 0.02% 30 0 0.0% Q4 2025 Jan 21, 2026
XTX Topco Ltd History Added to 117,900 238 0.01% 0.0% 31 +107,713 1057.36% Q4 2025 Feb 17, 2026
DEUTSCHE BANK AG\ History No change 108,762 219 0.0% 0.0% 32 0 0.0% Q4 2025 Feb 11, 2026
Quadrature Capital Ltd History Added to 104,231 210 0.0% 0.0% 33 +68,091 188.41% Q4 2025 Feb 17, 2026
GEODE CAPITAL MANAGEMENT, LLC History Added to 84,909 171 0.0% 0.0% 34 +36,087 73.92% Q4 2025 Feb 09, 2026
OneDigital Investment Advisors LLC History Added to 85,000 171 0.0% 0.0% 35 +5,000 6.25% Q4 2025 Feb 13, 2026
Lynx1 Capital Management LP History New 68,486 138 0.03% 36 +68,486 New Q4 2025 Feb 17, 2026
GROUP ONE TRADING LLC History Added to 59,288 119 0.0% 0.0% 37 +53,388 904.88% Q4 2025 Feb 12, 2026
Persistent Asset Partners Ltd History Added to 45,154 91 0.04% 0.05% 38 +8,874 24.46% Q4 2025 Feb 17, 2026
Velan Capital Investment Management LP History No change 45,000 90 0.05% 0.09% 39 0 0.0% Q4 2025 Feb 13, 2026
SIMPLEX TRADING, LLC History Added to 44,269 89 0.0% 40 +44,169 44169.0% Q4 2025 Feb 11, 2026
FIFTH THIRD BANCORP History No change 30,000 60 0.0% 0.0% 41 0 0.0% Q4 2025 Feb 02, 2026
RFG Advisory, LLC History No change 30,000 60 0.0% 0.0% 42 0 0.0% Q4 2025 Feb 03, 2026
Invesco Ltd. History New 25,347 51 0.0% 43 +25,347 New Q4 2025 Feb 19, 2026
MOODY LYNN & LIEBERSON, LLC History New 25,000 50 0.0% 44 +25,000 New Q4 2025 Jan 15, 2026
Vanguard Personalized Indexing Management, LLC History No change 22,314 45 0.0% 0.0% 45 0 0.0% Q4 2025 Feb 13, 2026
Keating Financial Advisory Services, Inc. History New 20,000 40 0.01% 47 +20,000 New Q4 2025 Feb 09, 2026
PNC FINANCIAL SERVICES GROUP, INC. History Added to 20,097 40 0.0% 0.0% 46 +570 2.92% Q4 2025 Feb 06, 2026
Mariner, LLC History No change 19,219 38 0.0% 0.0% 48 0 0.0% Q4 2025 Feb 13, 2026
GUGGENHEIM CAPITAL LLC History New 17,224 34 0.0% 49 +17,224 New Q4 2025 Feb 17, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History Reduced 14,000 28 0.0% 0.0% 50 -11,245 -44.54% Q4 2025 Feb 17, 2026
Atom Investors LP History No change 13,107 26 0.0% 0.0% 51 0 0.0% Q4 2025 Feb 17, 2026
ROYAL BANK OF CANADA History New 10,303 20 0.0% 53 +10,303 New Q4 2025 Feb 17, 2026
NANO CAP NEW MILLENNIUM GROWTH FUND L P History New 10,000 20 0.02% 54 +10,000 New Q4 2025 Feb 06, 2026
TRUIST FINANCIAL CORP History No change 10,000 20 0.0% 0.0% 52 0 0.0% Q4 2025 Feb 02, 2026
ADAR1 Capital Management, LLC History No change 10,000 20 0.0% 0.0% 55 0 0.0% Q4 2025 Feb 18, 2026
WELLS FARGO & COMPANY/MN History Reduced 4,000 8 0.0% 0.0% 56 -1,610 -28.7% Q4 2025 Feb 13, 2026
BlackRock, Inc. History No change 3,945 7 0.0% 0.0% 57 0 0.0% Q4 2025 Feb 12, 2026
Farther Finance Advisors, LLC History New 1,000 2 0.0% 60 +1,000 New Q4 2025 Jan 23, 2026
Tower Research Capital LLC (TRC) History Added to 1,211 2 0.0% 0.0% 58 +318 35.61% Q4 2025 Feb 17, 2026
Steward Partners Investment Advisory, LLC History No change 1,300 2 0.0% 0.0% 59 0 0.0% Q4 2025 Feb 12, 2026
PFS Partners, LLC History No change 1,000 2 0.0% 0.0% 61 0 0.0% Q4 2025 Jan 16, 2026
SBI Securities Co., Ltd. History Reduced 515 1 0.0% 0.0% 62 -37 -6.7% Q4 2025 Feb 03, 2026
Siren, L.L.C. History Closed out 0 0 0.13% -1,552,183 -100.0% Q3 2025 Nov 13, 2025
MACQUARIE GROUP LTD History Closed out 0 0 0.0% -620,000 -100.0% Q3 2025 Nov 13, 2025
Woodline Partners LP History Closed out 0 0 0.0% -92,140 -100.0% Q3 2025 Nov 14, 2025
CITIGROUP INC History Closed out 0 0 0.0% -22,724 -100.0% Q3 2025 Nov 10, 2025
Kestra Advisory Services, LLC History Closed out 0 0 0.0% -10,000 -100.0% Q3 2025 Nov 14, 2025
OSAIC HOLDINGS, INC. History Closed out 0 0 0.0% -6,000 -100.0% Q3 2025 Nov 14, 2025
JPMORGAN CHASE & CO History Reduced 283 0 -185 -39.53% Q4 2025 Feb 11, 2026
Activest Wealth Management History Closed out 0 0 -100 -100.0% Q3 2025 Nov 03, 2025
Rockefeller Capital Management L.P. History No change 34 0 0 0.0% Q4 2025 Mar 16, 2026
TD Waterhouse Canada Inc. History No change 40 0 0 0.0% Q4 2025 Jan 27, 2026
Medallion Wealth Advisors, LLC History No change 10 0 0 0.0% Q4 2025 Apr 24, 2026