CASSAVA SCIENCES INC - SAVA
Detailed investor-level table based on 13F positions.
Methodology:
Market value and % of portfolio use SEC reported VALUE ($000).
For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received.
Details.
Rows: 0
| Investor | History | Status | Shares held | Market value ($000) | % of portfolio | Previous % | Rank | Change in shares | % change in shares | Source | Date reported |
|---|---|---|---|---|---|---|---|---|---|---|---|
| VANGUARD GROUP INC | History | No change | 2,375,589 | 4,703 | 0.0% | 0.0% | 1 | 0 | 0.0% | Q4 2025 | Jan 29, 2026 |
| MARSHALL WACE, LLP | History | Reduced | 2,012,543 | 3,401 | 0.0% | 0.0% | 2 | -102,764 | -4.86% | Q1 2026 | May 14, 2026 |
| TWO SIGMA INVESTMENTS, LP | History | Added to | 1,988,814 | 3,361 | 0.0% | 0.0% | 3 | +1,346,413 | 209.59% | Q1 2026 | May 15, 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC | History | New | 1,930,943 | 3,263 | 0.0% | — | 4 | +1,930,943 | New | Q1 2026 | May 15, 2026 |
| BlackRock, Inc. | History | Reduced | 1,414,514 | 2,390 | 0.0% | 0.0% | 5 | -5,420 | -0.38% | Q1 2026 | May 13, 2026 |
| TWO SIGMA ADVISERS, LP | History | No change | 954,800 | 1,890 | 0.0% | 0.0% | 6 | 0 | 0.0% | Q4 2025 | Feb 17, 2026 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | History | Reduced | 749,178 | 1,266 | 0.0% | 0.0% | 7 | -251,140 | -25.11% | Q1 2026 | May 15, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | History | Added to | 596,242 | 1,008 | 0.0% | 0.0% | 8 | +50,273 | 9.21% | Q1 2026 | May 15, 2026 |
| D. E. Shaw & Co., Inc. | History | Added to | 559,205 | 945 | 0.0% | 0.0% | 9 | +89,879 | 19.15% | Q1 2026 | May 15, 2026 |
| GMT CAPITAL CORP | History | New | 450,100 | 760 | 0.03% | — | 10 | +450,100 | New | Q1 2026 | May 15, 2026 |
| GROUP ONE TRADING LLC | History | Reduced | 433,424 | 732 | 0.0% | 0.0% | 11 | -337,946 | -43.81% | Q1 2026 | May 13, 2026 |
| JANE STREET GROUP, LLC | History | Reduced | 328,564 | 555 | 0.0% | 0.0% | 12 | -349,373 | -51.53% | Q1 2026 | May 12, 2026 |
| RENAISSANCE TECHNOLOGIES LLC | History | New | 326,759 | 552 | 0.0% | — | 13 | +326,759 | New | Q1 2026 | May 14, 2026 |
| CITADEL ADVISORS LLC | History | Reduced | 311,100 | 525 | 0.0% | 0.0% | 14 | -162,600 | -34.33% | Q1 2026 | May 15, 2026 |
| ACADIAN ASSET MANAGEMENT LLC | History | No change | 284,213 | 478 | 0.0% | 0.0% | 15 | 0 | 0.0% | Q1 2026 | May 13, 2026 |
| VANGUARD FIDUCIARY TRUST CO | History | New | 273,931 | 462 | 0.0% | — | 16 | +273,931 | New | Q1 2026 | May 08, 2026 |
| SIMPLEX TRADING, LLC | History | Reduced | 247,195 | 417 | 0.0% | 0.0% | 17 | -229,270 | -48.12% | Q1 2026 | May 14, 2026 |
| DIMENSIONAL FUND ADVISORS LP | History | Added to | 239,906 | 405 | 0.0% | 0.0% | 19 | +99,849 | 71.29% | Q1 2026 | May 07, 2026 |
| STATE STREET CORP | History | Added to | 239,987 | 405 | 0.0% | 0.0% | 18 | +27,800 | 13.1% | Q1 2026 | May 15, 2026 |
| GSA CAPITAL PARTNERS LLP | History | Reduced | 217,844 | 368 | 0.02% | 0.05% | 20 | -70,035 | -24.33% | Q1 2026 | May 08, 2026 |
| JACOBS LEVY EQUITY MANAGEMENT, INC | History | Reduced | 209,080 | 353 | 0.0% | 0.0% | 21 | -37,907 | -15.35% | Q1 2026 | May 15, 2026 |
| CANADA PENSION PLAN INVESTMENT BOARD | History | Added to | 189,100 | 319 | 0.0% | 0.0% | 22 | +45,000 | 31.23% | Q1 2026 | May 15, 2026 |
| NORTHERN TRUST CORP | History | No change | 149,194 | 252 | 0.0% | 0.0% | 23 | 0 | 0.0% | Q1 2026 | May 14, 2026 |
| Connor, Clark & Lunn Investment Management Ltd. | History | Added to | 136,931 | 231 | 0.0% | 0.0% | 24 | +36,354 | 36.15% | Q1 2026 | May 11, 2026 |
| Walleye Trading LLC | History | Reduced | 135,368 | 228 | 0.0% | 0.0% | 25 | -155,710 | -53.49% | Q1 2026 | May 08, 2026 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | History | New | 132,693 | 224 | 0.0% | — | 26 | +132,693 | New | Q1 2026 | May 08, 2026 |
| FEDERATED HERMES, INC. | History | Added to | 115,097 | 194 | 0.0% | 0.0% | 27 | +23,618 | 25.82% | Q1 2026 | May 11, 2026 |
| Susquehanna Portfolio Strategies, LLC | History | Reduced | 100,772 | 170 | 0.0% | 0.01% | 28 | -106,063 | -51.28% | Q1 2026 | May 15, 2026 |
| Verition Fund Management LLC | History | Added to | 93,344 | 157 | 0.0% | 0.0% | 29 | +38,400 | 69.89% | Q1 2026 | May 15, 2026 |
| MILLENNIUM MANAGEMENT LLC | History | Reduced | 72,588 | 122 | 0.0% | 0.0% | 30 | -201,811 | -73.55% | Q1 2026 | May 15, 2026 |
| IMC-Chicago, LLC | History | New | 69,700 | 117 | 0.0% | — | 31 | +69,700 | New | Q1 2026 | May 05, 2026 |
| Gallacher Capital Management LLC | History | Reduced | 64,972 | 109 | 0.04% | 0.05% | 32 | -3 | -0.0% | Q1 2026 | May 05, 2026 |
| AMERICAN CENTURY COMPANIES INC | History | No change | 53,367 | 90 | 0.0% | 0.0% | 33 | 0 | 0.0% | Q1 2026 | May 15, 2026 |
| BARCLAYS PLC | History | Reduced | 42,379 | 71 | 0.0% | 0.0% | 34 | -6,083 | -12.55% | Q1 2026 | May 14, 2026 |
| GOLDMAN SACHS GROUP INC | History | Added to | 41,324 | 69 | 0.0% | 0.0% | 35 | +8,335 | 25.27% | Q1 2026 | May 15, 2026 |
| LPL Financial LLC | History | Reduced | 40,993 | 69 | 0.0% | 0.0% | 36 | -2,434 | -5.6% | Q1 2026 | May 06, 2026 |
| Point72 Asset Management, L.P. | History | Reduced | 39,121 | 66 | 0.0% | 0.0% | 37 | -260,458 | -86.94% | Q1 2026 | May 15, 2026 |
| Engineers Gate Manager LP | History | Added to | 39,494 | 66 | 0.0% | 0.0% | 38 | +7,840 | 24.77% | Q1 2026 | May 15, 2026 |
| Apollon Wealth Management, LLC | History | Reduced | 35,053 | 59 | 0.0% | 0.0% | 39 | -4,485 | -11.34% | Q1 2026 | Apr 22, 2026 |
| XTX Topco Ltd | History | Reduced | 33,303 | 56 | 0.0% | 0.0% | 40 | -1,625 | -4.65% | Q1 2026 | May 15, 2026 |
| PRICE T ROWE ASSOCIATES INC /MD/ | History | No change | 31,368 | 54 | 0.0% | 0.0% | 41 | 0 | 0.0% | Q1 2026 | May 15, 2026 |
| Invesco Ltd. | History | Added to | 31,130 | 52 | 0.0% | 0.0% | 42 | +13,010 | 71.8% | Q1 2026 | May 12, 2026 |
| OSAIC HOLDINGS, INC. | History | Reduced | 31,241 | 52 | 0.0% | 0.0% | 43 | -516 | -1.62% | Q1 2026 | May 15, 2026 |
| NINE MASTS CAPITAL Ltd | History | New | 27,107 | 45 | 0.01% | — | 44 | +27,107 | New | Q1 2026 | May 12, 2026 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | History | Reduced | 25,561 | 43 | 0.0% | 0.0% | 45 | -437 | -1.68% | Q1 2026 | May 15, 2026 |
| Graham Capital Management, L.P. | History | Reduced | 25,312 | 42 | 0.0% | 0.01% | 46 | -103,391 | -80.33% | Q1 2026 | May 15, 2026 |
| Bank of New York Mellon Corp | History | No change | 20,481 | 34 | 0.0% | 0.0% | 47 | 0 | 0.0% | Q1 2026 | May 05, 2026 |
| MGO ONE SEVEN LLC | History | Reduced | 19,826 | 33 | 0.0% | 0.0% | 48 | -1,436 | -6.75% | Q1 2026 | May 14, 2026 |
| MORGAN STANLEY | History | Reduced | 17,990 | 30 | 0.0% | 0.0% | 49 | -52,449 | -74.46% | Q1 2026 | May 15, 2026 |
| Catalyst Funds Management Pty Ltd | History | New | 18,100 | 30 | 0.01% | — | 50 | +18,100 | New | Q1 2026 | May 11, 2026 |
| RAYMOND JAMES FINANCIAL INC | History | Reduced | 17,104 | 28 | 0.0% | 0.0% | 51 | -13,360 | -43.86% | Q1 2026 | May 14, 2026 |
| Vanguard Global Advisers, LLC | History | New | 15,897 | 26 | 0.0% | — | 52 | +15,897 | New | Q1 2026 | May 08, 2026 |
| Cetera Investment Advisers | History | Reduced | 14,466 | 24 | 0.0% | 0.0% | 53 | -2,423 | -14.35% | Q1 2026 | May 13, 2026 |
| Vanguard Personalized Indexing Management, LLC | History | Added to | 13,891 | 23 | 0.0% | 0.0% | 54 | +1,026 | 7.98% | Q1 2026 | May 14, 2026 |
| MAYPORT, LLC | History | No change | 13,400 | 22 | 0.0% | 0.01% | 55 | 0 | 0.0% | Q1 2026 | Apr 21, 2026 |
| TWO SIGMA SECURITIES, LLC | History | New | 12,696 | 21 | 0.0% | — | 56 | +12,696 | New | Q1 2026 | May 15, 2026 |
| JOHNSON INVESTMENT COUNSEL INC | History | No change | 12,000 | 20 | 0.0% | 0.0% | 57 | 0 | 0.0% | Q1 2026 | May 01, 2026 |
| UBS Group AG | History | Reduced | 11,603 | 19 | 0.0% | 0.0% | 58 | -18,266 | -61.15% | Q1 2026 | May 05, 2026 |
| Marex Group plc | History | New | 10,500 | 17 | 0.0% | — | 59 | +10,500 | New | Q1 2026 | May 13, 2026 |
| HSBC HOLDINGS PLC | History | No change | 10,000 | 16 | 0.0% | 0.0% | 60 | 0 | 0.0% | Q1 2026 | Apr 30, 2026 |
| WELLS FARGO & COMPANY/MN | History | Reduced | 8,421 | 14 | 0.0% | 0.0% | 61 | -7,883 | -48.35% | Q1 2026 | Jul 08, 2026 |
| Russell Investments Group, Ltd. | History | Reduced | 7,320 | 12 | 0.0% | 0.0% | 62 | -813 | -10.0% | Q1 2026 | May 08, 2026 |
| FMR LLC | History | Reduced | 6,062 | 10 | 0.0% | 0.0% | 63 | -1,430 | -19.09% | Q1 2026 | May 15, 2026 |
| AlphaQuest LLC | History | No change | 5,026 | 9 | 0.0% | 0.0% | 64 | 0 | 0.0% | Q4 2025 | Feb 09, 2026 |
| Federation des caisses Desjardins du Quebec | History | No change | 4,695 | 7 | 0.0% | 0.0% | 65 | 0 | 0.0% | Q1 2026 | May 13, 2026 |
| Activest Wealth Management | History | No change | 4,001 | 6 | 0.0% | 0.0% | 66 | 0 | 0.0% | Q1 2026 | Apr 15, 2026 |
| Advisory Services Network, LLC | History | New | 3,100 | 5 | 0.0% | — | 68 | +3,100 | New | Q1 2026 | May 15, 2026 |
| NewEdge Advisors, LLC | History | Reduced | 3,300 | 5 | 0.0% | 0.0% | 67 | -725 | -18.01% | Q1 2026 | Jun 02, 2026 |
| Optiver Holding B.V. | History | New | 2,851 | 4 | 0.0% | — | 70 | +2,851 | New | Q1 2026 | Jun 02, 2026 |
| EverSource Wealth Advisors, LLC | History | Reduced | 2,559 | 4 | 0.0% | 0.0% | 69 | -551 | -17.72% | Q1 2026 | May 15, 2026 |
| ROYAL BANK OF CANADA | History | Reduced | 1,553 | 3 | 0.0% | 0.0% | 71 | -3,945 | -71.75% | Q1 2026 | May 15, 2026 |
| Tower Research Capital LLC (TRC) | History | Reduced | 2,076 | 3 | 0.0% | 0.0% | 72 | -2,842 | -57.79% | Q1 2026 | May 15, 2026 |
| Signature Equity Partners, LLC | History | No change | 2,000 | 3 | 0.0% | 0.0% | 73 | 0 | 0.0% | Q1 2026 | May 13, 2026 |
| NATIONAL BANK OF CANADA /FI/ | History | Added to | 1,710 | 2 | 0.0% | 0.0% | 75 | +200 | 13.25% | Q1 2026 | May 14, 2026 |
| PNC FINANCIAL SERVICES GROUP, INC. | History | Reduced | 1,681 | 2 | 0.0% | 0.0% | 74 | -51 | -2.94% | Q1 2026 | May 08, 2026 |
| SBI Securities Co., Ltd. | History | Reduced | 1,231 | 2 | 0.0% | 0.0% | 78 | -10 | -0.81% | Q1 2026 | Apr 27, 2026 |
| MAI Capital Management | History | No change | 1,500 | 2 | 0.0% | 0.0% | 76 | 0 | 0.0% | Q1 2026 | May 15, 2026 |
| RHUMBLINE ADVISERS | History | No change | 1,734 | 2 | 0.0% | 0.0% | 77 | 0 | 0.0% | Q1 2026 | May 12, 2026 |
| Smartleaf Asset Management LLC | History | No change | 1,369 | 2 | 0.0% | 0.0% | 79 | 0 | 0.0% | Q1 2026 | May 15, 2026 |
| MidFirst Bank | History | No change | 1,000 | 1 | 0.0% | 0.0% | 80 | 0 | 0.0% | Q1 2026 | May 15, 2026 |
| Jump Financial, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -91,620 | -100.0% | Q1 2026 | May 14, 2026 |
| OMERS ADMINISTRATION Corp | History | Closed out | 0 | 0 | — | 0.0% | — | -83,900 | -100.0% | Q1 2026 | May 15, 2026 |
| HRT FINANCIAL LP | History | Closed out | 0 | 0 | — | 0.0% | — | -74,892 | -100.0% | Q1 2026 | May 14, 2026 |
| Headlands Technologies LLC | History | Closed out | 0 | 0 | — | 0.01% | — | -50,866 | -100.0% | Q1 2026 | May 13, 2026 |
| Virtu Financial LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -48,832 | -100.0% | Q1 2026 | May 14, 2026 |
| Lighthouse Investment Partners, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -29,520 | -100.0% | Q1 2026 | May 14, 2026 |
| Caitong International Asset Management Co., Ltd | History | Reduced | 107 | 0 | — | 0.01% | — | -27,105 | -99.61% | Q1 2026 | May 11, 2026 |
| Squarepoint Ops LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -26,300 | -100.0% | Q1 2026 | May 15, 2026 |
| BANK OF AMERICA CORP /DE/ | History | Closed out | 0 | 0 | — | 0.0% | — | -13,531 | -100.0% | Q1 2026 | May 15, 2026 |
| Belpointe Asset Management LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -12,259 | -100.0% | Q1 2026 | Apr 28, 2026 |
| Fortis Capital Advisors, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -12,259 | -100.0% | Q1 2026 | Apr 28, 2026 |
| SmartHarvest Portfolios, LLC | History | Closed out | 0 | 0 | — | 0.01% | — | -12,072 | -100.0% | Q1 2026 | Apr 20, 2026 |
| DIADEMA PARTNERS LP | History | Closed out | 0 | 0 | — | 0.0% | — | -10,600 | -100.0% | Q1 2026 | May 15, 2026 |
| BNP PARIBAS FINANCIAL MARKETS | History | Reduced | 425 | 0 | — | 0.0% | — | -10,584 | -96.14% | Q1 2026 | May 12, 2026 |
| LMR Partners LLP | History | Closed out | 0 | 0 | — | 0.0% | — | -10,000 | -100.0% | Q1 2026 | May 15, 2026 |
| TANG CAPITAL MANAGEMENT LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -7,073 | -100.0% | Q1 2026 | May 15, 2026 |
| FLAGSHIP HARBOR ADVISORS, LLC | History | Closed out | 0 | 0 | — | 0.0% | — | -620 | -100.0% | Q1 2026 | Apr 28, 2026 |
| SALEM INVESTMENT COUNSELORS INC | History | New | 275 | 0 | — | — | — | +275 | New | Q1 2026 | Apr 29, 2026 |
| Strategic Wealth Partners, Ltd. | History | Closed out | 0 | 0 | — | — | — | -275 | -100.0% | Q1 2026 | May 12, 2026 |
| MATHER GROUP, LLC. | History | New | 250 | 0 | — | — | — | +250 | New | Q1 2026 | Apr 13, 2026 |
| Farther Finance Advisors, LLC | History | Reduced | 16 | 0 | — | — | — | -78 | -82.98% | Q1 2026 | Apr 07, 2026 |
| Arax Advisory Partners | History | Reduced | 368 | 0 | — | — | — | -77 | -17.3% | Q1 2026 | May 13, 2026 |
| JONES FINANCIAL COMPANIES LLLP | History | Added to | 462 | 0 | — | — | — | +67 | 16.96% | Q1 2026 | May 15, 2026 |
| Silicon Valley Capital Partners | History | New | 57 | 0 | — | — | — | +57 | New | Q1 2026 | May 19, 2026 |
| CITIGROUP INC | History | Reduced | 20 | 0 | — | — | — | -42 | -67.74% | Q1 2026 | May 11, 2026 |
| Byrne Asset Management LLC | History | Closed out | 0 | 0 | — | — | — | -40 | -100.0% | Q1 2026 | Apr 02, 2026 |
| Persistent Asset Partners Ltd | History | Closed out | 0 | 0 | — | 0.0% | — | -30 | -100.0% | Q1 2026 | May 12, 2026 |
| Covestor Ltd | History | Closed out | 0 | 0 | — | — | — | -28 | -100.0% | Q1 2026 | May 05, 2026 |
| Laurel Wealth Advisors LLC | History | Closed out | 0 | 0 | — | — | — | -17 | -100.0% | Q1 2026 | May 12, 2026 |
| Rockefeller Capital Management L.P. | History | Closed out | 0 | 0 | — | — | — | -5 | -100.0% | Q1 2026 | May 14, 2026 |
| JPMORGAN CHASE & CO | History | No change | 13 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | May 13, 2026 |
| HARBOUR INVESTMENTS, INC. | History | No change | 250 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | May 15, 2026 |
| CREATIVE FINANCIAL DESIGNS INC /ADV | History | No change | 40 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | Apr 13, 2026 |
| HM PAYSON & CO | History | No change | 50 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | Apr 13, 2026 |
| NISA INVESTMENT ADVISORS, LLC | History | No change | 362 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | Apr 30, 2026 |
| BESSEMER GROUP INC | History | No change | 24 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | May 06, 2026 |
| HANTZ FINANCIAL SERVICES, INC. | History | No change | 50 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | May 01, 2026 |
| CWM, LLC | History | No change | 455 | 0 | — | 0.0% | — | 0 | 0.0% | Q1 2026 | May 14, 2026 |
| IFP Advisors, Inc | History | No change | 10 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | Apr 13, 2026 |
| Parallel Advisors, LLC | History | No change | 244 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | Jun 02, 2026 |
| Steward Partners Investment Advisory, LLC | History | No change | 312 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | May 08, 2026 |
| Larson Financial Group LLC | History | No change | 10 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | May 15, 2026 |
| Golden State Wealth Management, LLC | History | No change | 36 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | Apr 28, 2026 |
| SOA Wealth Advisors, LLC. | History | No change | 78 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | May 20, 2026 |
| SageView Advisory Group, LLC | History | No change | 110 | 0 | — | — | — | 0 | 0.0% | Q4 2025 | Feb 17, 2026 |
| TD Waterhouse Canada Inc. | History | No change | 400 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | May 12, 2026 |
| LRI Investments, LLC | History | No change | 10 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | Apr 30, 2026 |
| Legacy Wealth Managment, LLC/ID | History | No change | 258 | 0 | — | — | — | 0 | 0.0% | Q1 2026 | May 07, 2026 |