Sionna Therapeutics, Inc. - SION

Detailed investor-level table based on 13F positions.
Early Q1 2026 data: only 5 institutional holders reported so far. The full shareholder list will grow as more funds file with the SEC.

Shareholders (13F)

Quarter: Q4 2025 · Compare: Q3 2025
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
RA CAPITAL MANAGEMENT, L.P. History Reduced 9,905,045 407,493 4.17% 3.79% 1 -540,277 -5.17% Q4 2025 Feb 17, 2026
TPG GP A, LLC History No change 6,744,962 277,487 10.33% 10.8% 2 0 0.0% Q4 2025 Feb 13, 2026
ORBIMED ADVISORS LLC History Reduced 3,561,655 146,526 2.99% 2.56% 3 -143,304 -3.87% Q4 2025 Feb 17, 2026
VIKING GLOBAL INVESTORS LP History No change 3,195,181 131,449 0.35% 0.24% 4 0 0.0% Q4 2025 Feb 17, 2026
Atlas Venture Life Science Advisors, LLC History Reduced 2,995,602 123,239 14.24% 14.13% 5 -619,925 -17.15% Q4 2025 Feb 13, 2026
Enavate Sciences GP, LLC History No change 2,478,030 101,946 20.12% 22.25% 6 0 0.0% Q4 2025 Feb 17, 2026
BlackRock, Inc. History Added to 1,291,599 53,136 0.0% 0.0% 7 +446,994 52.92% Q4 2025 Feb 12, 2026
JPMORGAN CHASE & CO History Reduced 1,231,819 50,677 0.0% 0.0% 8 -746,807 -37.74% Q4 2025 Feb 11, 2026
VANGUARD GROUP INC History Added to 1,184,951 48,748 0.0% 0.0% 9 +41,797 3.66% Q4 2025 Jan 29, 2026
PERCEPTIVE ADVISORS LLC History No change 1,179,098 48,508 0.86% 1.0% 10 0 0.0% Q4 2025 Feb 17, 2026
JENNISON ASSOCIATES LLC History Added to 1,115,278 45,882 0.03% 0.02% 11 +117,903 11.82% Q4 2025 Jan 30, 2026
CITADEL ADVISORS LLC History Added to 1,087,325 44,732 0.01% 0.0% 12 +1,051,402 2926.82% Q4 2025 Feb 17, 2026
DEERFIELD MANAGEMENT COMPANY, L.P. History No change 970,590 39,930 0.51% 0.44% 13 0 0.0% Q4 2025 Feb 17, 2026
Aberdeen Group plc History Reduced 839,960 34,555 0.05% 0.04% 14 -110,587 -11.63% Q4 2025 Jan 16, 2026
PRICE T ROWE ASSOCIATES INC /MD/ History Added to 831,373 34,203 0.0% 0.0% 15 +193,613 30.36% Q4 2025 Feb 17, 2026
STATE STREET CORP History Added to 693,395 28,526 0.0% 0.0% 16 +453,196 188.68% Q4 2025 Feb 13, 2026
EVENTIDE ASSET MANAGEMENT, LLC History New 639,045 26,290 0.41% 17 +639,045 New Q4 2025 Feb 13, 2026
BAKER BROS. ADVISORS LP History No change 400,000 16,456 0.1% 0.09% 18 0 0.0% Q4 2025 Feb 17, 2026
GEODE CAPITAL MANAGEMENT, LLC History Added to 380,042 15,638 0.0% 0.0% 19 +63,478 20.05% Q4 2025 Feb 09, 2026
Siren, L.L.C. History Reduced 300,000 12,342 0.37% 0.37% 20 -25,000 -7.69% Q4 2025 Feb 13, 2026
Soleus Capital Management, L.P. History Reduced 268,500 11,046 0.41% 0.61% 21 -145,000 -35.07% Q4 2025 Feb 12, 2026
Kalehua Capital Management LLC History New 197,072 8,107 8.02% 22 +197,072 New Q4 2025 Feb 13, 2026
SUPERSTRING CAPITAL MANAGEMENT LP History New 180,593 7,429 3.98% 23 +180,593 New Q4 2025 Feb 17, 2026
FRANKLIN RESOURCES INC History Reduced 175,483 7,219 0.0% 0.0% 24 -66,664 -27.53% Q4 2025 Feb 11, 2026
Alyeska Investment Group, L.P. History Reduced 136,222 5,604 0.02% 0.02% 25 -50,000 -26.85% Q4 2025 Feb 13, 2026
CHARLES SCHWAB INVESTMENT MANAGEMENT INC History Added to 123,686 5,088 0.0% 0.0% 26 +12,190 10.93% Q4 2025 Feb 13, 2026
Artia Global Partners LP History New 119,741 4,926 0.7% 27 +119,741 New Q4 2025 Feb 17, 2026
TD ASSET MANAGEMENT INC History Added to 113,352 4,663 0.0% 0.0% 28 +26,270 30.17% Q4 2025 Feb 10, 2026
NORTHERN TRUST CORP History Added to 112,116 4,612 0.0% 0.0% 29 +14,405 14.74% Q4 2025 Feb 17, 2026
Invesco Ltd. History New 111,162 4,573 0.0% 30 +111,162 New Q4 2025 Feb 19, 2026
AMERIPRISE FINANCIAL INC History Reduced 101,643 4,181 0.0% 0.0% 31 -51,508 -33.63% Q4 2025 Feb 17, 2026
Rock Springs Capital Management LP History No change 99,429 4,090 0.21% 0.17% 32 0 0.0% Q4 2025 Feb 17, 2026
UBS Group AG History Added to 89,177 3,668 0.0% 0.0% 33 +42,511 91.1% Q4 2025 Jan 29, 2026
DRIEHAUS CAPITAL MANAGEMENT LLC History No change 83,850 3,449 0.02% 0.02% 34 0 0.0% Q4 2025 Feb 17, 2026
MILLENNIUM MANAGEMENT LLC History Reduced 80,546 3,313 0.0% 0.0% 35 -133,539 -62.38% Q4 2025 Feb 17, 2026
Ensign Peak Advisors, Inc History New 79,862 3,285 0.01% 36 +79,862 New Q4 2025 Feb 12, 2026
Longaeva Partners L.P. History Added to 79,729 3,280 0.28% 0.26% 37 +18,272 29.73% Q4 2025 Feb 17, 2026
MANUFACTURERS LIFE INSURANCE COMPANY, THE History New 69,424 2,872 0.0% 38 +69,424 New Q4 2025 Feb 13, 2026
SEVEN GRAND MANAGERS, LLC History New 50,000 2,057 0.16% 39 +50,000 New Q4 2025 Feb 10, 2026
MORGAN STANLEY History Added to 49,876 2,051 0.0% 0.0% 40 +27,039 118.4% Q4 2025 Feb 13, 2026
BARCLAYS PLC History Added to 48,172 1,981 0.0% 0.0% 41 +30,529 173.04% Q4 2025 Feb 13, 2026
BANK OF AMERICA CORP /DE/ History Added to 43,567 1,792 0.0% 0.0% 42 +37,026 566.06% Q4 2025 Feb 17, 2026
SILVERARC CAPITAL MANAGEMENT, LLC History Reduced 41,460 1,705 0.24% 0.43% 43 -67,341 -61.89% Q4 2025 Feb 12, 2026
WELLINGTON MANAGEMENT GROUP LLP History Reduced 38,347 1,577 0.0% 0.0% 44 -3,887 -9.2% Q4 2025 Feb 17, 2026
ALPS ADVISORS INC History New 36,648 1,507 0.01% 45 +36,648 New Q4 2025 Feb 12, 2026
GOLDMAN SACHS GROUP INC History Added to 36,269 1,492 0.0% 0.0% 46 +24,091 197.82% Q4 2025 Mar 25, 2026
Bank of New York Mellon Corp History Added to 35,134 1,445 0.0% 0.0% 47 +7,671 27.93% Q4 2025 Feb 10, 2026
POLEN CAPITAL MANAGEMENT LLC History No change 31,258 1,285 0.01% 0.0% 48 0 0.0% Q4 2025 Feb 12, 2026
Rafferty Asset Management, LLC History New 24,690 1,015 0.0% 49 +24,690 New Q4 2025 Feb 13, 2026
Nuveen, LLC History Added to 23,734 976 0.0% 0.0% 50 +7,694 47.97% Q4 2025 Feb 12, 2026
Russell Investments Group, Ltd. History Added to 21,941 902 0.0% 0.0% 51 +20,919 2046.87% Q4 2025 Feb 17, 2026
RHUMBLINE ADVISERS History Added to 17,694 727 0.0% 0.0% 52 +454 2.63% Q4 2025 Feb 13, 2026
WELLS FARGO & COMPANY/MN History Added to 17,551 722 0.0% 0.0% 53 +9,975 131.67% Q4 2025 Feb 13, 2026
Squarepoint Ops LLC History Added to 16,360 673 0.0% 0.0% 54 +6,198 60.99% Q4 2025 Feb 13, 2026
ALLIANCEBERNSTEIN L.P. History New 15,620 642 0.0% 55 +15,620 New Q4 2025 Feb 17, 2026
SG Americas Securities, LLC History New 10,691 440 0.0% 56 +10,691 New Q4 2025 Jan 09, 2026
China Universal Asset Management Co., Ltd. History Added to 10,272 422 0.03% 0.01% 57 +5,272 105.44% Q4 2025 Jan 29, 2026
DEUTSCHE BANK AG\ History Added to 10,029 412 0.0% 0.0% 58 +433 4.51% Q4 2025 Feb 11, 2026
PROFUND ADVISORS LLC History New 9,213 379 0.01% 59 +9,213 New Q4 2025 Feb 06, 2026
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. History Added to 8,915 367 0.0% 0.0% 60 +3,272 57.98% Q4 2025 Feb 17, 2026
MetLife Investment Management, LLC History Added to 8,565 352 0.0% 0.0% 61 +532 6.62% Q4 2025 Feb 12, 2026
INTECH INVESTMENT MANAGEMENT LLC History Added to 7,589 312 0.0% 0.0% 62 +103 1.38% Q4 2025 Feb 10, 2026
KENNEDY CAPITAL MANAGEMENT LLC History New 6,752 277 0.01% 63 +6,752 New Q4 2025 Feb 13, 2026
TWO SIGMA INVESTMENTS, LP History New 6,400 263 0.0% 64 +6,400 New Q4 2025 Feb 17, 2026
Virtus Investment Advisers, LLC History Reduced 6,220 255 0.07% 0.06% 65 -478 -7.14% Q4 2025 Feb 17, 2026
AMERICAN CENTURY COMPANIES INC History New 6,180 254 0.0% 66 +6,180 New Q4 2025 Feb 13, 2026
DARK FOREST CAPITAL MANAGEMENT LP History New 5,991 246 0.01% 67 +5,991 New Q4 2025 Feb 17, 2026
D. E. Shaw & Co., Inc. History New 5,742 236 0.0% 68 +5,742 New Q4 2025 Feb 17, 2026
NEW YORK STATE COMMON RETIREMENT FUND History No change 5,300 218 0.0% 0.0% 69 0 0.0% Q4 2025 Feb 12, 2026
CITIGROUP INC History Added to 5,185 213 0.0% 0.0% 70 +4,498 654.73% Q4 2025 Feb 13, 2026
XTX Topco Ltd History New 4,926 202 0.01% 71 +4,926 New Q4 2025 Feb 17, 2026
ProShare Advisors LLC History New 4,903 201 0.0% 72 +4,903 New Q4 2025 Feb 06, 2026
LOS ANGELES CAPITAL MANAGEMENT LLC History New 5,189 197 0.0% 73 +5,189 New Q4 2025 Feb 11, 2026
CIBC Private Wealth Group LLC History New 4,500 185 0.0% 74 +4,500 New Q4 2025 Feb 12, 2026
Police & Firemen's Retirement System of New Jersey History Added to 4,232 174 0.0% 0.0% 75 +998 30.86% Q4 2025 Feb 13, 2026
AlphaCentric Advisors LLC History New 2,720 111 0.11% 76 +2,720 New Q4 2025 Feb 12, 2026
BNP PARIBAS FINANCIAL MARKETS History Reduced 2,264 93 0.0% 0.0% 77 -116 -4.87% Q4 2025 Feb 10, 2026
Mirae Asset Global Investments Co., Ltd. History New 2,169 89 0.0% 78 +2,169 New Q4 2025 Jan 26, 2026
Legal & General Group Plc History Reduced 1,682 69 0.0% 0.0% 79 -5,692 -77.19% Q4 2025 Feb 09, 2026
BALYASNY ASSET MANAGEMENT L.P. History New 1,406 57 0.0% 80 +1,406 New Q4 2025 Feb 17, 2026
Ameritas Investment Partners, Inc. History Added to 1,302 53 0.0% 0.0% 81 +43 3.42% Q4 2025 Feb 11, 2026
Tower Research Capital LLC (TRC) History Reduced 1,129 46 0.0% 0.0% 82 -3,361 -74.86% Q4 2025 Feb 17, 2026
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM History Added to 988 40 0.0% 0.0% 83 +217 28.15% Q4 2025 Feb 17, 2026
GF FUND MANAGEMENT CO. LTD. History New 876 36 0.0% 84 +876 New Q4 2025 Jan 27, 2026
ROYAL BANK OF CANADA History New 489 21 0.0% 86 +489 New Q4 2025 Feb 17, 2026
AMALGAMATED BANK History Added to 504 21 0.0% 0.0% 85 +83 19.71% Q4 2025 Feb 05, 2026
FMR LLC History Added to 384 15 0.0% 0.0% 87 +150 64.1% Q4 2025 Feb 17, 2026
Farther Finance Advisors, LLC History New 190 7 0.0% 88 +190 New Q4 2025 Jan 23, 2026
GAMMA Investing LLC History Added to 177 7 0.0% 0.0% 89 +24 15.69% Q4 2025 Jan 05, 2026
Daiwa Securities Group Inc. History New 149 6 0.0% 90 +149 New Q4 2025 Feb 11, 2026
Sterling Capital Management LLC History Added to 105 4 0.0% 91 +75 250.0% Q4 2025 Feb 13, 2026
CWM, LLC History Added to 80 3 0.0% 0.0% 92 +20 33.33% Q4 2025 Jan 26, 2026
US BANCORP \DE\ History Reduced 65 2 0.0% 0.0% 93 -46 -41.44% Q4 2025 Jan 30, 2026
Aster Capital Management (DIFC) Ltd History Reduced 37 1 0.0% 0.01% 96 -372 -90.95% Q4 2025 Feb 17, 2026
Rockefeller Capital Management L.P. History New 48 1 0.0% 95 +48 New Q4 2025 Mar 16, 2026
Allworth Financial LP History New 28 1 0.0% 94 +28 New Q4 2025 Feb 05, 2026
Hughes Financial Services, LLC History Reduced 25 1 0.0% 0.0% 97 -19 -43.18% Q4 2025 Feb 11, 2026
BRAIDWELL LP History Closed out 0 0 0.27% -314,013 -100.0% Q3 2025 Nov 14, 2025
Holocene Advisors, LP History Closed out 0 0 0.0% -50,000 -100.0% Q3 2025 Nov 14, 2025
MARSHALL WACE, LLP History Closed out 0 0 0.0% -30,103 -100.0% Q3 2025 Nov 13, 2025
RENAISSANCE TECHNOLOGIES LLC History Closed out 0 0 0.0% -14,600 -100.0% Q3 2025 Nov 13, 2025
Jain Global LLC History Closed out 0 0 0.0% -8,513 -100.0% Q3 2025 Nov 14, 2025
FEDERATED HERMES, INC. History Closed out 0 0 0.0% -113 -100.0% Q3 2025 Nov 03, 2025
Arax Advisory Partners History Closed out 0 0 0.0% -92 -100.0% Q3 2025 Nov 14, 2025
ROTHSCHILD INVESTMENT LLC History New 1 0 +1 New Q4 2025 Feb 10, 2026
PNC FINANCIAL SERVICES GROUP, INC. History No change 5 0 0 0.0% Q4 2025 Feb 06, 2026
EverSource Wealth Advisors, LLC History No change 20 0 0 0.0% Q4 2025 Feb 06, 2026