Silence Therapeutics plc - SLN

Detailed investor-level table based on 13F positions.
Early Q1 2026 data: only 3 institutional holders reported so far. The full shareholder list will grow as more funds file with the SEC.

Shareholders (13F)

Quarter: Q4 2025 · Compare: Q3 2025
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
TCG Crossover Management, LLC History No change 3,033,560 18,444 0.61% 0.77% 1 0 0.0% Q4 2025 Feb 17, 2026
Siren, L.L.C. History No change 2,911,438 17,701 0.53% 0.59% 2 0 0.0% Q4 2025 Feb 13, 2026
Redmile Group, LLC History No change 2,164,777 13,161 0.97% 1.09% 3 0 0.0% Q4 2025 Feb 17, 2026
Nantahala Capital Management, LLC History Added to 1,542,427 9,377 0.31% 0.19% 4 +500,000 47.96% Q4 2025 Feb 13, 2026
Vivo Capital, LLC History No change 1,105,454 6,721 0.43% 0.46% 5 0 0.0% Q4 2025 Feb 13, 2026
Nextech Invest, Ltd. History No change 952,400 5,790 0.56% 0.75% 6 0 0.0% Q4 2025 Feb 17, 2026
GREAT POINT PARTNERS LLC History New 808,032 4,912 1.59% 7 +808,032 New Q4 2025 Feb 17, 2026
MILLENNIUM MANAGEMENT LLC History Added to 659,592 4,010 0.0% 0.0% 8 +361,080 120.96% Q4 2025 Feb 17, 2026
5AM Venture Management, LLC History No change 476,200 2,895 0.91% 0.9% 9 0 0.0% Q4 2025 Feb 17, 2026
Tetragon Partners GP Ltd History New 365,369 2,221 0.47% 10 +365,369 New Q4 2025 Feb 17, 2026
MORGAN STANLEY History Reduced 324,630 1,973 0.0% 0.0% 11 -883,094 -73.12% Q4 2025 Feb 13, 2026
Ikarian Capital, LLC History Reduced 865,784 1,731 0.14% 0.13% 12 -35,000 -3.89% Q4 2025 Feb 18, 2026
CITADEL ADVISORS LLC History Added to 258,861 1,573 0.0% 0.0% 13 +237,356 1103.72% Q4 2025 Feb 17, 2026
SG Americas Securities, LLC History Reduced 256,340 1,559 0.0% 0.01% 14 -51,949 -16.85% Q4 2025 Jan 09, 2026
Ishara Investments LP History New 240,000 1,459 1.67% 15 +240,000 New Q4 2025 Feb 17, 2026
BOOTHBAY FUND MANAGEMENT, LLC History Reduced 209,088 1,271 0.02% 0.02% 16 -70,549 -25.23% Q4 2025 Feb 17, 2026
UBS Group AG History Reduced 207,513 1,261 0.0% 0.0% 17 -99,850 -32.49% Q4 2025 Jan 29, 2026
Lombard Odier Asset Management (USA) Corp History Reduced 255,901 1,154 0.11% 0.48% 18 -1,589,047 -86.13% Q4 2025 Feb 17, 2026
M28 Capital Management LP History No change 185,100 1,125 0.82% 1.41% 19 0 0.0% Q4 2025 Feb 13, 2026
HSBC HOLDINGS PLC History Reduced 172,834 1,071 0.0% 0.0% 20 -39 -0.02% Q4 2025 Mar 20, 2026
BANK OF MONTREAL /CAN/ History Added to 160,474 975 0.0% 0.0% 21 +6,692 4.35% Q4 2025 Feb 12, 2026
MARSHALL WACE, LLP History Added to 155,680 946 0.0% 0.0% 22 +72,461 87.07% Q4 2025 Feb 13, 2026
Seven Fleet Capital Management LP History New 147,600 897 0.61% 23 +147,600 New Q4 2025 Apr 02, 2026
Point72 Asset Management, L.P. History New 114,070 693 0.0% 24 +114,070 New Q4 2025 Feb 17, 2026
Opaleye Management Inc. History New 78,926 479 0.06% 25 +78,926 New Q4 2025 Apr 13, 2026
BlackRock, Inc. History Added to 73,153 444 0.0% 0.0% 26 +11,321 18.31% Q4 2025 Feb 12, 2026
Quadrature Capital Ltd History New 54,380 330 0.0% 27 +54,380 New Q4 2025 Feb 17, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History New 41,866 254 0.0% 28 +41,866 New Q4 2025 Feb 17, 2026
TWO SIGMA INVESTMENTS, LP History Reduced 39,344 239 0.0% 0.0% 29 -23,903 -37.79% Q4 2025 Feb 17, 2026
Qube Research & Technologies Ltd History New 34,962 212 0.0% 30 +34,962 New Q4 2025 Feb 17, 2026
GEODE CAPITAL MANAGEMENT, LLC History No change 29,538 179 0.0% 0.0% 31 0 0.0% Q4 2025 Feb 09, 2026
JANE STREET GROUP, LLC History New 29,168 177 0.0% 32 +29,168 New Q4 2025 Feb 12, 2026
RAYMOND JAMES FINANCIAL INC History New 25,000 152 0.0% 33 +25,000 New Q4 2025 Feb 18, 2026
ADAR1 Capital Management, LLC History Added to 23,643 143 0.01% 0.01% 34 +5,000 26.82% Q4 2025 Feb 18, 2026
GOLDMAN SACHS GROUP INC History Reduced 18,114 110 0.0% 0.0% 35 -4,530 -20.01% Q4 2025 Mar 25, 2026
TWO SIGMA ADVISERS, LP History Reduced 15,900 96 0.0% 0.0% 36 -26,700 -62.68% Q4 2025 Feb 17, 2026
China Universal Asset Management Co., Ltd. History Added to 13,653 83 0.01% 0.0% 37 +5,421 65.85% Q4 2025 Jan 29, 2026
RHUMBLINE ADVISERS History Added to 12,999 79 0.0% 0.0% 38 +7,134 121.64% Q4 2025 Feb 13, 2026
BNP PARIBAS FINANCIAL MARKETS History Added to 12,027 73 0.0% 0.0% 39 +11,427 1904.5% Q4 2025 Feb 10, 2026
XTX Topco Ltd History New 11,718 71 0.0% 40 +11,718 New Q4 2025 Feb 17, 2026
GAMMA Investing LLC History Added to 10,112 61 0.0% 0.0% 41 +197 1.99% Q4 2025 Jan 05, 2026
JPMORGAN CHASE & CO History Added to 7,942 48 0.0% 0.0% 42 +176 2.27% Q4 2025 Feb 11, 2026
BARCLAYS PLC History Reduced 5,065 30 0.0% 0.0% 43 -2,071 -29.02% Q4 2025 Feb 13, 2026
SIMPLEX TRADING, LLC History Added to 3,991 24 0.0% 0.0% 44 +3,340 513.06% Q4 2025 Feb 11, 2026
BANK OF AMERICA CORP /DE/ History Reduced 2,966 18 0.0% 0.0% 45 -565 -16.0% Q4 2025 Feb 17, 2026
JONES FINANCIAL COMPANIES LLLP History No change 2,500 15 0.0% 0.0% 46 0 0.0% Q4 2025 Feb 17, 2026
Tower Research Capital LLC (TRC) History Added to 2,448 14 0.0% 0.0% 47 +1 0.04% Q4 2025 Feb 17, 2026
Mirae Asset Global Investments Co., Ltd. History Added to 2,282 13 0.0% 0.0% 48 +466 25.66% Q4 2025 Jan 26, 2026
CITIGROUP INC History Reduced 1,621 9 0.0% 0.0% 49 -152 -8.57% Q4 2025 Feb 13, 2026
Parallel Advisors, LLC History No change 1,300 7 0.0% 0.0% 50 0 0.0% Q4 2025 Feb 11, 2026
Global Retirement Partners, LLC History New 1,000 6 0.0% 51 +1,000 New Q4 2025 Feb 06, 2026
GF FUND MANAGEMENT CO. LTD. History Reduced 922 5 0.0% 0.0% 52 -56 -5.73% Q4 2025 Jan 27, 2026
Frazier Life Sciences Management, L.P. History Closed out 0 0 0.15% -970,130 -100.0% Q3 2025 Nov 14, 2025
CANTOR FITZGERALD, L. P. History Closed out 0 0 0.04% -801,306 -100.0% Q3 2025 Feb 17, 2026
Woodline Partners LP History Closed out 0 0 0.0% -62,459 -100.0% Q3 2025 Nov 14, 2025
OSAIC HOLDINGS, INC. History Reduced 3 0 0.0% -62,168 -100.0% Q4 2025 Feb 17, 2026
Virtus Investment Advisers, LLC History Closed out 0 0 0.03% -20,374 -100.0% Q3 2025 Nov 14, 2025
HRT FINANCIAL LP History Closed out 0 0 0.0% -10,887 -100.0% Q3 2025 Nov 14, 2025
EHP Funds Inc. History Closed out 0 0 0.05% -10,673 -100.0% Q3 2025 Nov 13, 2025
Cambridge Investment Research Advisors, Inc. History Closed out 0 0 0.0% -10,194 -100.0% Q3 2025 Nov 12, 2025
WEXFORD CAPITAL LP History Closed out 0 0 0.01% -7,708 -100.0% Q3 2025 Nov 14, 2025
ACADIAN ASSET MANAGEMENT LLC History Closed out 0 0 0.0% -4,218 -100.0% Q3 2025 Nov 13, 2025
PRINCIPAL SECURITIES, INC. History Closed out 0 0 -17 -100.0% Q3 2025 Nov 12, 2025
ROYAL BANK OF CANADA History New 16 0 +16 New Q4 2025 Feb 17, 2026
SageView Advisory Group, LLC History New 11 0 +11 New Q4 2025 Feb 17, 2026
SBI Securities Co., Ltd. History Reduced 28 0 -1 -3.45% Q4 2025 Feb 03, 2026
Steward Partners Investment Advisory, LLC History No change 100 0 0 0.0% Q4 2025 Feb 12, 2026
Rockefeller Capital Management L.P. History No change 45 0 0 0.0% Q4 2025 Mar 16, 2026