Spero Therapeutics, Inc. - SPRO

Sector: Healthcare · Industry: Pharmaceutical Preparations

Website: No information yet · Social: No information yet

Company profile

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Q4 2025 · Q3 2025

Value (USD)

Total reported value ($000)

$49.45M

QoQ value delta ($000)

+$28.16M (+132.3%)

Implied price effect (QoQ)

+24.03%

Total shares

21,231,099

QoQ shares delta

+9,894,742 (+87.28%)

Total shares held by funds (by quarter)

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Top 25 only Full list

Early Q1 2026 data: only 2 institutional holders reported so far. More will appear as funds file with the SEC.

Manager	Value ($000)	Shares	% of 13F
GSK plc	21,414	9,190,606	2.68%
PFIZER INC	5,504	2,362,348	2.33%
VANGUARD GROUP INC	4,854	2,083,462	0.0%
RENAISSANCE TECHNOLOGIES LLC	2,981	1,279,522	0.0%
Alphabet Inc.	2,073	889,979	0.08%
Anson Funds Management LP	1,456	625,062	0.14%
GEODE CAPITAL MANAGEMENT, LLC	1,233	529,195	0.0%
CITADEL ADVISORS LLC	1,097	470,964	0.0%
BlackRock, Inc.	1,010	433,616	0.0%
TWO SIGMA INVESTMENTS, LP	868	372,570	0.0%
SUSQUEHANNA INTERNATIONAL GROUP, LLP	684	293,700	0.0%
Informed Momentum Co LLC	508	218,084	0.06%
TWO SIGMA ADVISERS, LP	504	216,600	0.0%
STATE STREET CORP	489	210,151	0.0%
JANE STREET GROUP, LLC	458	196,944	0.0%
Ionic Capital Management LLC	456	195,939	0.06%
GSA CAPITAL PARTNERS LLP	417	178,930	0.04%
INTREPID FAMILY OFFICE LLC	384	165,000	0.33%
SEI INVESTMENTS CO	307	132,010	0.0%
OMERS ADMINISTRATION Corp	305	131,127	0.0%
NORTHERN TRUST CORP	281	120,984	0.0%
Squarepoint Ops LLC	278	119,434	0.0%
UBS Group AG	271	116,447	0.0%
BRIDGEWAY CAPITAL MANAGEMENT, LLC	267	114,800	0.01%
ADAR1 Capital Management, LLC	265	113,839	0.02%