Taysha Gene Therapies, Inc. - TSHA

Sector: Healthcare · Industry: Biological Products, (No Diagnostic Substances)

Website: No information yet · Social: No information yet

Company profile

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Q1 2026 · Q4 2025

Value (USD)

Total reported value ($000)

$1.293B

QoQ value delta ($000)

-$194.2M (-13.06%)

Implied price effect (QoQ)

-16.52%

Total shares

281,566,364

QoQ shares delta

+11,204,953 (+4.14%)

Total shares held by funds (by quarter)

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Top 25 only Full list

Partial Q1 2026 data: 193 holders have filed so far. Prior holders are carried forward until their next 13F confirms a change.

Manager	Value ($000)	Shares	% of 13F
RA CAPITAL MANAGEMENT, L.P.	105,293	23,555,648	1.12%
GOLDMAN SACHS GROUP INC	99,992	22,369,645	0.01%
Avoro Capital Advisors LLC	96,999	21,700,000	0.95%
BlackRock, Inc.	82,094	18,365,608	0.0%
Vestal Point Capital, LP	80,460	18,000,000	2.25%
MORGAN STANLEY	80,305	17,965,371	0.0%
VANGUARD GROUP INC	72,972	13,267,805	0.0%
FMR LLC	64,016	14,321,255	0.0%
RTW INVESTMENTS, LP	61,150	13,680,248	0.61%
STATE STREET CORP	50,104	11,209,078	0.0%
VANGUARD CAPITAL MANAGEMENT LLC	45,734	10,231,502	0.0%
Octagon Capital Advisors LP	39,603	8,859,911	4.38%
Siren, L.L.C.	39,469	8,829,913	1.09%
Polar Capital Holdings Plc	25,274	5,654,340	0.09%
GEODE CAPITAL MANAGEMENT, LLC	24,732	5,531,955	0.0%
GordonMD Global Investments LP	22,215	737,550	15.47%
D. E. Shaw & Co., Inc.	19,790	4,427,301	0.01%
BAKER BROS. ADVISORS LP	17,901	4,004,756	0.1%
MILLENNIUM MANAGEMENT LLC	14,669	3,281,820	0.01%
Casdin Capital, LLC	14,527	3,250,000	1.1%
ADAR1 Capital Management, LLC	13,318	2,979,429	0.78%
HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND	12,888	2,883,301	0.02%
DEERFIELD MANAGEMENT COMPANY, L.P.	12,168	2,722,165	0.14%
BARCLAYS PLC	11,444	2,812,010	0.0%
NORGES BANK	10,107	1,837,800	0.0%