PERCEPTIVE ADVISORS LLC

Q1 2026 13F-HR Holdings

Location
New York, NY
Holdings as of
3/31/2026
Date filed
5/15/2026
Form type
13F-HR
Num holdings
94
Total value ($000)
$5,110,910
Net value change ($000)
-499,374 (-8.9%)
New positions
18
Sold out positions
38
Turnover %
24.1%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q4 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
CNTA 135,914 186.3%
ASND 119,680 51.9%
SYRE 90,278 89.8%
RLAY 80,923 502.6%
PRAX 67,677 11.5%
ROIV 56,222 32.4%
BCRX 46,104 186.9%
CELC 41,741 13.2%
IONS 37,845 NEW
DAWN 37,644 NEW
Top Reduces (Value $000, Stocks/ETFs)
EXAS -121,921 -100.0%
ACLX -95,588 -100.0%
BSX -93,348 -100.0%
FOLD -90,721 -100.0%
Astria Therapeutics, Inc. -84,894 -100.0%
VRDN -71,788 -75.8%
RYTM -66,117 -24.3%
APGE -46,264 -26.3%
DHR -45,784 -100.0%
BLTE -42,030 -63.4%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 55,035 (1.1% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type