BAKER BROS. ADVISORS LP
Q1 2021 13F-HR Holdings
Net value change ($000)
-3,478,314
(-13.1%)
New positions
11
Sold out positions
12
Turnover %
2.3%
Sector allocation + QoQ delta (equities-only)
Snapshot: Change Analysis
Compared to Q4 2020
Methodology:
sector metrics are equities-only;
instrument mix chart is ex-options;
options exposure is shown separately.
Why this matters.
Top Adds (Value $000, Stocks/ETFs)
| ONC | 1,046,584 | 34.7% |
| IMCR | 107,307 | NEW |
| TIL | 97,654 | NEW |
| TLIS | 97,337 | NEW |
| Global Blood Therapeutics, Inc. | 91,250 | 228.9% |
| DSGN | 42,955 | NEW |
| Achilles Therapeutics plc | 42,887 | NEW |
| DBVT | 39,605 | 103.4% |
| BCRX | 34,685 | 36.7% |
| AMARIN CORP PLC | 27,396 | 20.0% |
Top Reduces (Value $000, Stocks/ETFs)
| Seagen Inc. | -1,714,749 | -20.7% |
| ACAD | -1,158,923 | -51.7% |
| ALXN | -758,169 | -55.4% |
| KOD | -465,256 | -22.8% |
| PRLD | -285,323 | -39.4% |
| INCY | -182,584 | -6.6% |
| ASND | -134,176 | -22.7% |
| BMRN | -92,437 | -13.9% |
| Mirati Therapeutics, Inc. | -68,149 | -22.0% |
| ABCL | -65,627 | -15.6% |
Instrument mix + QoQ Δ (ex-options)
How this table is calculated:
SEC
VALUE ($000) is used as reported.
For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received.
Column % is bucket-based:
non-options share is calculated inside non-option total, options share is calculated inside options total.
Details.
Filter:
Instrument:
| Issuer Name | Ticker | Sector | Industry | Class | History | Value ($000) | % | Shares | Shares Δ | Shares Δ% | Value Δ ($000) | Value Δ% | Principal | Option Type |
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