BAKER BROS. ADVISORS LP

Q2 2021 13F-HR Holdings

Location
New York, NY
Holdings as of
6/30/2021
Date filed
8/16/2021
Form type
13F-HR
Num holdings
120
Total value ($000)
$22,769,898
Net value change ($000)
-295,425 (-1.3%)
New positions
6
Sold out positions
15
Turnover %
3.7%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q1 2021
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
Seagen Inc. 901,852 13.7%
INCY 93,235 3.6%
Verve Therapeutics, Inc. 85,346 NEW
APLS 71,753 99.9%
BCRX 71,689 55.5%
LEGN 64,974 1936.6%
BMRN 60,183 10.5%
VSTM 45,433 108.1%
JBIO 32,614 NEW
HRTX 29,030 29.9%
Top Reduces (Value $000, Stocks/ETFs)
ALXN -610,617 -100.0%
KOD -259,025 -16.5%
Invitae Corp -256,092 -42.6%
PRLD -148,820 -33.9%
ABCL -124,984 -35.2%
ACAD -59,094 -5.5%
ONC -57,061 -1.4%
AMARIN CORP PLC -48,410 -29.5%
ChemoCentryx, Inc. -33,650 -100.0%
MDGL -29,325 -16.7%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type