RA CAPITAL MANAGEMENT, L.P.

Q2 2026 13F-HR Holdings

Location
Boston, MA
Holdings as of
6/30/2026
Date filed
8/14/2026
Form type
13F-HR
Num holdings
84
Total value ($000)
$11,507,522
Net value change ($000)
+2,069,778 (21.9%)
New positions
18
Sold out positions
18
Turnover %
66.5%
Sector allocation + QoQ delta (equities-only)
Prev filing: 5/15/2026 Next filing: — SEC filing

Snapshot: Change Analysis

Compared to Q1 2026
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
Ascendis Pharma AS 2,742,281 NEW
PARABILIS MEDICINES INC 791,906 NEW
HEMAB THERAPEUTICS HOLDINGS 286,811 NEW
RYTM 160,404 27.7%
ABVX 150,925 NEW
ORKA 147,951 NEW
ARTV 110,715 174.5%
GHRS 97,344 90.2%
NTLA 76,596 NEW
BCAX 71,108 49.3%
Top Reduces (Value $000, Stocks/ETFs)
ASND -2,351,687 -100.0%
DNTH -219,177 -100.0%
PRAX -120,430 -100.0%
NUVL -105,686 -40.7%
SRPT -84,920 -100.0%
SYRE -81,795 -100.0%
TYRA -77,583 -16.6%
VOR -52,202 -54.1%
FULC -46,434 -100.0%
GERN -40,223 -42.3%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type