RTW INVESTMENTS, LP

Q2 2025 13F-HR Holdings

Location
New York, NY
Holdings as of
6/30/2025
Date filed
8/14/2025
Form type
13F-HR
Num holdings
73
Total value ($000)
$7,021,315
Net value change ($000)
+482,943 (7.4%)
New positions
11
Sold out positions
6
Turnover %
7.3%
Sector allocation + QoQ delta (equities-only)
Prev filing: 5/15/2025 Next filing: 2/17/2026 SEC filing

Snapshot: Change Analysis

Compared to Q1 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
NBIX 133,492 NEW
VRNA 107,777 59.6%
INSM 80,449 35.0%
ZLAB 80,265 70.8%
DGX 73,065 436.2%
NTRA 71,417 19.5%
ABT 60,388 NEW
ACAD 52,183 36.8%
GH 44,572 NEW
PTGX 41,558 15.0%
Top Reduces (Value $000, Stocks/ETFs)
AXSM -182,528 -53.5%
ALKERMES PLC -93,373 -41.1%
GMED -82,350 -100.0%
RCKT -74,642 -63.3%
MDGL -57,000 -8.6%
TARS -44,291 -26.0%
ARGX -27,374 -6.9%
ARVN -23,407 -100.0%
CYTK -19,456 -17.8%
GKOS -18,700 -100.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type