RTW INVESTMENTS, LP

Q2 2025 13F-HR Detailed Holdings

Location
New York, NY
Holdings as of
6/30/2025
Date filed
8/14/2025
Form type
13F-HR
Num holdings
73
Total value ($000)
$7,021,315
Net value change ($000)
+482,943 (7.4%)
New positions
11
Sold out positions
6
Turnover %
7.3%
Sector allocation + QoQ delta (equities-only)

Holdings broken out by other managers reported in the original SEC filing. View aggregated holdings

Prev filing: 5/15/2025 Next filing: 2/17/2026 SEC filing
You are on the SEC detailed breakdown page. Rows are shown as reported in the filing (including other manager, discretion, and voting authority fields), and are not merged like the standard holdings view. Switch to aggregated holdings.

Snapshot: Change Analysis

Compared to Q1 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
NBIX 133,492 NEW
VRNA 107,777 59.6%
INSM 80,449 35.0%
ZLAB 80,265 70.8%
DGX 73,065 436.2%
NTRA 71,417 19.5%
ABT 60,388 NEW
ACAD 52,183 36.8%
GH 44,572 NEW
PTGX 41,558 15.0%
Top Reduces (Value $000, Stocks/ETFs)
AXSM -182,528 -53.5%
ALKERMES PLC -93,373 -41.1%
GMED -82,350 -100.0%
RCKT -74,642 -63.3%
MDGL -57,000 -8.6%
TARS -44,291 -26.0%
ARGX -27,374 -6.9%
ARVN -23,407 -100.0%
CYTK -19,456 -17.8%
GKOS -18,700 -100.0%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
Filter:
Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type Discretion Other Manager Sole Shared None