Opaleye Management Inc.

Q1 2014 13F-HR Holdings

Location
Cambridge, MA
Holdings as of
3/31/2014
Date filed
5/15/2014
Form type
13F-HR
Num holdings
30
Total value ($000)
$135,373
Net value change ($000)
+7,986 (6.3%)
New positions
12
Sold out positions
4
Turnover %
67.1%
Sector allocation + QoQ delta (equities-only)

Snapshot: Change Analysis

Compared to Q4 2013
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
TVTX 24,448 NEW
CHIMERIX INC 12,242 NEW
GenMark Diagnostics, Inc. 4,324 NEW
INSPIREMD INC 3,611 122.4%
BIND THERAPEUTICS INC 2,983 140.4%
Epizyme, Inc. 2,630 NEW
Flexion Therapeutics Inc 2,229 NEW
EVOK 1,956 NEW
CELGENE CORP RIGHT 12/31/2030 1,881 NEW
ARIAD PHARMACEUTICALS INC 1,603 13.5%
Top Reduces (Value $000, Stocks/ETFs)
GENTIUM SPA SPONSORED ADR -29,240 -100.0%
GERN -10,901 -82.6%
SUNSHINE HEART INC -3,773 -91.5%
INTERCEPT PHARMACEUTICALS, INC. -3,642 -100.0%
LGND -2,506 -51.6%
INFIQ -1,671 -100.0%
MEDIVATION -1,600 -100.0%
NPS PHARMACEUTICALS INC -1,455 -24.5%
PHARMACYCLICS INC -1,435 -11.1%
LAB -1,069 -21.2%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type