Opaleye Management Inc.

Q2 2025 13F-HR/A Holdings

Location
Boston, MA
Holdings as of
6/30/2025
Date filed
8/15/2025
Form type
13F-HR/A - RESTATEMENT
Num holdings
41
Total value ($000)
$494,141
Net value change ($000)
—
New positions
39
Sold out positions
0
Turnover %
100.0%
Sector allocation + QoQ delta (equities-only)
Prev filing: 5/15/2014 Next filing: 11/14/2025 SEC filing

Snapshot: Change Analysis

Compared to previous filing: —
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
HROW 119,259 —
ETON 40,755 —
IMNM 32,825 —
SNWV 32,203 —
LQDA 30,839 —
CDXS 30,744 —
RYTM 30,015 —
TGTX 19,255 —
OCUL 14,802 —
ARVN 12,365 —
Top Reduces (Value $000, Stocks/ETFs)
—
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
Filter:
Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type