GREAT POINT PARTNERS LLC

Q3 2025 13F-HR Holdings

Location
Greenwich, CT
Holdings as of
9/30/2025
Date filed
11/14/2025
Form type
13F-HR
Num holdings
30
Total value ($000)
$242,496
Net value change ($000)
+88,694 (57.7%)
New positions
10
Sold out positions
8
Turnover %
50.1%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Prev filing: 8/14/2025 Next filing: 2/17/2026 SEC filing

Snapshot: Change Analysis

Compared to Q2 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
NKTR 17,070 NEW
SLNO 15,210 NEW
ASND 14,911 NEW
ZURA 13,194 396.3%
APGE 12,078 NEW
DNTH 10,459 NEW
AMLX 10,283 80.2%
RZLT 9,518 70.4%
EPRX 7,080 NEW
PHVS 3,870 NEW
Top Reduces (Value $000, Stocks/ETFs)
IONS -14,521 -73.5%
LEGN -8,722 -70.2%
AKBA -7,229 -100.0%
EOLS -6,632 -100.0%
ACLX -6,585 -100.0%
KALV -3,653 -100.0%
CNTA -2,957 -100.0%
SRRK -2,182 -100.0%
PMN -1,280 -100.0%
AKRO -610 -11.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 2,975 (1.2% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type