GREAT POINT PARTNERS LLC

Q3 2025 13F-HR Detailed Holdings

Location
Greenwich, CT
Holdings as of
9/30/2025
Date filed
11/14/2025
Form type
13F-HR
Num holdings
30
Total value ($000)
$242,496
Net value change ($000)
+88,694 (57.7%)
New positions
10
Sold out positions
8
Turnover %
50.1%
Sector allocation + QoQ delta (equities-only)

Holdings broken out by other managers reported in the original SEC filing. View aggregated holdings

You are on the SEC detailed breakdown page. Rows are shown as reported in the filing (including other manager, discretion, and voting authority fields), and are not merged like the standard holdings view. Switch to aggregated holdings.

Snapshot: Change Analysis

Compared to Q2 2025
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
NKTR 17,070 NEW
SLNO 15,210 NEW
ASND 14,911 NEW
ZURA 13,194 396.3%
APGE 12,078 NEW
DNTH 10,459 NEW
AMLX 10,283 80.2%
RZLT 9,518 70.4%
EPRX 7,080 NEW
PHVS 3,870 NEW
Top Reduces (Value $000, Stocks/ETFs)
IONS -14,521 -73.5%
LEGN -8,722 -70.2%
AKBA -7,229 -100.0%
EOLS -6,632 -100.0%
ACLX -6,585 -100.0%
KALV -3,653 -100.0%
CNTA -2,957 -100.0%
SRRK -2,182 -100.0%
PMN -1,280 -100.0%
AKRO -610 -11.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 2,975 (1.2% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type Discretion Other Manager Sole Shared None

Other Managers

Num Name File Number
1 JAY JEFFREY R 028-12517
2 Nordahl Lillian 028-24470