Paradigm Biocapital Advisors LP

Q3 2024 13F-HR Holdings

Location
New York, NY
Holdings as of
9/30/2024
Date filed
11/14/2024
Form type
13F-HR
Num holdings
33
Total value ($000)
$2,955,927
Net value change ($000)
+342,911 (13.1%)
New positions
7
Sold out positions
11
Turnover %
27.6%
Sector allocation + QoQ delta (equities-only)
Prev filing: 8/14/2024 Next filing: 2/14/2025 SEC filing

Snapshot: Change Analysis

Compared to Q2 2024
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
NUVL 164,693 47.5%
ACLX 121,664 57.3%
VERA 48,481 NEW
MLTX 46,965 NEW
ONC 44,977 NEW
JANX 43,523 66.4%
SYRE 37,280 NEW
RVMD 36,889 18.1%
PLRX 34,801 NEW
EWTX 32,562 77.7%
Top Reduces (Value $000, Stocks/ETFs)
SRPT -149,717 -100.0%
Cerevel Therapeutics Holdings, Inc. -95,294 -100.0%
ASND -90,598 -100.0%
XENE -79,667 -100.0%
LEGN -53,295 -100.0%
IRON -48,304 -39.6%
BBIO -27,597 -100.0%
OLMA -19,804 -23.2%
VRNA -10,427 -100.0%
ALXO -9,501 -100.0%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 98,438 (3.3% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type