Siren, L.L.C.

Q1 2025 13F-HR/A Detailed Holdings

Location
New York, NY
Holdings as of
3/31/2025
Date filed
5/23/2025
Form type
13F-HR/A - RESTATEMENT
Num holdings
117
Total value ($000)
$1,772,780
Net value change ($000)
-490,708 (-21.7%)
New positions
24
Sold out positions
25
Turnover %
24.3%
Sector allocation + QoQ delta (equities-only)

Holdings broken out by other managers reported in the original SEC filing. View aggregated holdings

You are on the SEC detailed breakdown page. Rows are shown as reported in the filing (including other manager, discretion, and voting authority fields), and are not merged like the standard holdings view. Switch to aggregated holdings.

Snapshot: Change Analysis

Compared to Q4 2024
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
BPMC 64,273 NEW
IRON 53,207 NEW
SLNO 36,154 228.6%
EWTX 17,715 90.4%
ONC 14,979 12.4%
RYTM 14,701 NEW
SMMT 13,407 NEW
SLDB 12,443 83.0%
Merus N.V. 10,935 33.2%
GOOGL 6,516 491.8%
Top Reduces (Value $000, Stocks/ETFs)
SRRK -102,397 -25.6%
ARGX -70,753 -100.0%
SpringWorks Therapeutics, Inc. -49,776 -100.0%
NMRA -42,241 -90.6%
MDGL -38,862 -100.0%
SEPN -37,685 -74.7%
APLS -33,477 -37.3%
KYMR -30,785 -25.8%
CRNX -25,666 -31.2%
ARWR -20,538 -37.6%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type Discretion Other Manager Sole Shared None

Other Managers

Num Name File Number
1 Invus Financial Advisors, LLC 028-19938
2 Invus Group, LLC 028-24462