Siren, L.L.C.

Q1 2025 13F-HR/A Holdings

Location
New York, NY
Holdings as of
3/31/2025
Date filed
5/23/2025
Form type
13F-HR/A - RESTATEMENT
Num holdings
116
Total value ($000)
$1,772,780
Net value change ($000)
-490,708 (-21.7%)
New positions
24
Sold out positions
25
Turnover %
24.3%
Sector allocation + QoQ delta (equities-only)

Holdings aggregated across other managers listed in the original SEC filing. View detailed breakdown

Prev filing: 2/14/2025 Next filing: 8/13/2025 SEC filing

Snapshot: Change Analysis

Compared to Q4 2024
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
BPMC 64,273 NEW
IRON 53,207 NEW
SLNO 36,154 228.6%
EWTX 17,715 90.4%
ONC 14,979 12.4%
RYTM 14,701 NEW
SMMT 13,407 NEW
SLDB 12,443 83.0%
Merus N.V. 10,935 33.2%
GOOGL 6,516 491.8%
Top Reduces (Value $000, Stocks/ETFs)
SRRK -102,397 -25.6%
ARGX -70,753 -100.0%
SpringWorks Therapeutics, Inc. -49,776 -100.0%
NMRA -42,241 -90.6%
MDGL -38,862 -100.0%
SEPN -37,685 -74.7%
APLS -33,477 -37.3%
KYMR -30,785 -25.8%
CRNX -25,666 -31.2%
ARWR -20,538 -37.6%
Instrument mix + QoQ Δ (ex-options)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type