Siren, L.L.C.

Q2 2026 13F-HR Detailed Holdings

Location
New York, NY
Holdings as of
6/30/2026
Date filed
8/13/2026
Form type
13F-HR
Num holdings
119
Total value ($000)
$4,941,404
Net value change ($000)
+1,334,025 (37.0%)
New positions
25
Sold out positions
10
Turnover %
13.6%
Sector allocation + QoQ delta (equities-only)

Holdings broken out by other managers reported in the original SEC filing. View aggregated holdings

You are on the SEC detailed breakdown page. Rows are shown as reported in the filing (including other manager, discretion, and voting authority fields), and are not merged like the standard holdings view. Switch to aggregated holdings.

Snapshot: Change Analysis

Compared to Q1 2026
Methodology: sector metrics are equities-only; instrument mix chart is ex-options; options exposure is shown separately. Why this matters.
Top Adds (Value $000, Stocks/ETFs)
MANE 108,448 114.1%
Parabilis Medicines Inc 81,898 NEW
ABVX 76,758 NEW
Hemab Therapeutics Holdings Inc 76,649 NEW
TNGX 74,820 63.2%
KYMR 71,221 26.8%
RLAY 68,292 NEW
RYTM 63,063 99.9%
ELVN 60,799 207.8%
RVMD 60,509 56.0%
Top Reduces (Value $000, Stocks/ETFs)
CNTA -41,844 -100.0%
ENGN -35,774 -100.0%
FULC -18,025 -100.0%
WAVE LIFE SCIENCES LTD -17,763 -100.0%
GPCR -17,191 -26.8%
QURE -16,350 -100.0%
CRNX -15,974 -23.1%
OLMA -10,166 -14.3%
EWTX -10,162 -7.3%
DBVT -8,339 -21.5%
Instrument mix + QoQ Δ (ex-options)
Derivatives reported exposure ($000): 15,607 (0.3% of total reported value)
How this table is calculated: SEC VALUE ($000) is used as reported. For derivatives (PUT/CALL/WARRANT/RIGHT), SEC value represents reported underlying exposure, not premium cash paid/received. Column % is bucket-based: non-options share is calculated inside non-option total, options share is calculated inside options total. Details.
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Instrument:
Issuer Name Ticker Sector Industry Class History Value ($000) % Shares Shares Δ Shares Δ% Value Δ ($000) Value Δ% Principal Option Type Discretion Other Manager Sole Shared None

Other Managers

Num Name File Number
1 Invus Financial Advisors, LLC 028-19938
2 Invus Group, LLC 028-24462