482931102
Detailed investor-level table based on 13F positions.
Methodology:
Market value and % of portfolio use SEC reported VALUE ($000).
For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received.
Details.
Rows: 0
| Investor | History | Status | Shares held | Market value ($000) | % of portfolio | Previous % | Rank | Change in shares | % change in shares | Source | Date reported |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BAIN CAPITAL INVESTORS LLC | History | No change | 26,255,581 | 578,410 | 12.01% | 12.01% | 1 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Bain Capital Life Sciences Investors, LLC | History | No change | 22,583,268 | 497,509 | 29.58% | 29.58% | 2 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| RTW INVESTMENTS, LP | History | No change | 10,776,820 | 237,413 | 2.03% | 2.03% | 3 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| CANADA PENSION PLAN INVESTMENT BOARD | History | No change | 7,304,688 | 160,922 | 0.09% | 0.09% | 4 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| BlackRock, Inc. | History | No change | 3,928,604 | 86,547 | 0.0% | 0.0% | 5 | 0 | 0.0% | Q2 2026 | Aug 07, 2026 |
| PRICE T ROWE ASSOCIATES INC /MD/ | History | No change | 3,534,410 | 77,864 | 0.01% | 0.01% | 6 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| CITADEL ADVISORS LLC | History | No change | 3,240,787 | 71,394 | 0.01% | 0.01% | 7 | 0 | 0.0% | Q2 2026 | Sep 02, 2026 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | History | No change | 3,208,286 | 70,678 | 0.1% | 0.1% | 8 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| WELLINGTON MANAGEMENT GROUP LLP | History | No change | 2,919,110 | 64,307 | 0.01% | 0.01% | 9 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Atlas Venture Life Science Advisors, LLC | History | No change | 5,171,282 | 59,056 | 9.36% | 12.93% | 10 | 0 | 0.0% | Q3 2026 | Nov 10, 2026 |
| Royalty Pharma Sub-Manager, LLC | History | No change | 2,455,357 | 54,091 | 22.36% | 22.36% | 11 | 0 | 0.0% | Q2 2026 | Aug 21, 2026 |
| FMR LLC | History | Added to | 4,659,885 | 53,215 | 0.0% | 0.0% | 12 | +689,020 | 17.35% | Q3 2026 | Nov 10, 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC | History | No change | 1,693,958 | 37,317 | 0.0% | 0.0% | 13 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | History | No change | 1,652,507 | 36,404 | 0.0% | 0.0% | 14 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| STATE STREET CORP | History | Added to | 2,241,320 | 25,595 | 0.0% | 0.0% | 15 | +1,373,160 | 158.17% | Q3 2026 | Nov 12, 2026 |
| Siren, L.L.C. | History | No change | 2,214,286 | 25,287 | 0.6% | 0.99% | 16 | 0 | 0.0% | Q3 2026 | Nov 12, 2026 |
| FARALLON CAPITAL MANAGEMENT, L.L.C. | History | No change | 1,100,000 | 24,233 | 0.11% | 0.11% | 17 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Frazier Life Sciences Management, L.P. | History | No change | 1,100,000 | 24,233 | 0.53% | 0.53% | 18 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Trails Edge Capital Partners, LP | History | No change | 984,786 | 21,694 | 3.44% | 3.44% | 19 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Jupiter Topco LLC | History | No change | 970,857 | 21,344 | 0.01% | 0.01% | 20 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| AMERIPRISE FINANCIAL INC | History | No change | 821,331 | 18,093 | 0.0% | 0.0% | 21 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Deep Track Capital, LP | History | No change | 700,000 | 15,421 | 0.22% | 0.22% | 22 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | History | Added to | 1,206,848 | 13,785 | 0.0% | 0.0% | 23 | +73,733 | 6.51% | Q3 2026 | Nov 06, 2026 |
| EVENTIDE ASSET MANAGEMENT, LLC | History | No change | 616,720 | 13,586 | 0.18% | 0.18% | 24 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Vestal Point Capital, LP | History | No change | 575,000 | 12,667 | 0.3% | 0.3% | 25 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Cormorant Asset Management, LP | History | No change | 550,000 | 12,116 | 0.62% | 0.62% | 26 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Catalio Capital Management, LP | History | No change | 468,750 | 10,326 | 1.94% | 1.94% | 27 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| GOLDMAN SACHS GROUP INC | History | No change | 421,034 | 9,275 | 0.0% | 0.0% | 28 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | History | No change | 362,910 | 7,994 | 0.0% | 0.0% | 29 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| NORTHERN TRUST CORP | History | No change | 354,431 | 7,808 | 0.0% | 0.0% | 30 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| VANGUARD FIDUCIARY TRUST CO | History | No change | 290,128 | 6,391 | 0.0% | 0.0% | 31 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| UBS Group AG | History | Reduced | 469,584 | 5,362 | 0.0% | 0.0% | 32 | -503,099 | -51.72% | Q3 2026 | Nov 10, 2026 |
| FRANKLIN TEMPLETON INC | History | Added to | 401,443 | 5,138 | 0.0% | 0.0% | 33 | +1,420 | 0.35% | Q3 2026 | Nov 12, 2026 |
| Aberdeen Group plc | History | Added to | 432,661 | 4,940 | 0.01% | 0.0% | 34 | +292,661 | 209.04% | Q3 2026 | Nov 10, 2026 |
| FEDERATED HERMES, INC. | History | Reduced | 403,693 | 4,610 | 0.01% | 0.01% | 35 | -30,376 | -7.0% | Q3 2026 | Nov 12, 2026 |
| SEVEN GRAND MANAGERS, LLC | History | No change | 175,000 | 3,855 | 0.16% | 0.16% | 36 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| BNP PARIBAS FINANCIAL MARKETS | History | Added to | 310,269 | 3,543 | 0.0% | 0.0% | 37 | +303,269 | 4332.41% | Q3 2026 | Nov 12, 2026 |
| BALYASNY ASSET MANAGEMENT L.P. | History | No change | 154,838 | 3,411 | 0.0% | 0.0% | 38 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | History | No change | 149,817 | 3,300 | 0.0% | 0.0% | 39 | 0 | 0.0% | Q2 2026 | Sep 09, 2026 |
| TD ASSET MANAGEMENT INC | History | No change | 147,698 | 3,253 | 0.0% | 0.0% | 40 | 0 | 0.0% | Q2 2026 | Aug 04, 2026 |
| Nantahala Capital Management, LLC | History | No change | 140,000 | 3,084 | 0.1% | 0.1% | 41 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| a16z Capital Management, L.L.C. | History | No change | 140,000 | 3,084 | 0.02% | 0.02% | 42 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| EXCHANGE TRADED CONCEPTS, LLC | History | Added to | 260,799 | 2,978 | 0.01% | 0.02% | 43 | +108,298 | 71.01% | Q3 2026 | Oct 28, 2026 |
| ALPS ADVISORS INC | History | Added to | 171,739 | 1,961 | 0.01% | 0.01% | 44 | +40,739 | 31.1% | Q3 2026 | Nov 02, 2026 |
| Avidity Partners Management LP | History | No change | 80,000 | 1,762 | 0.28% | 0.28% | 45 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Nuveen, LLC | History | Added to | 147,192 | 1,680 | 0.0% | 0.0% | 46 | +58,396 | 65.76% | Q3 2026 | Nov 10, 2026 |
| Ghisallo Capital Management LLC | History | No change | 75,000 | 1,652 | 0.03% | 0.03% | 47 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Bank of New York Mellon Corp | History | Added to | 140,934 | 1,609 | 0.0% | 0.0% | 48 | +2,535 | 1.83% | Q3 2026 | Nov 05, 2026 |
| Rock Springs Capital Management LP | History | No change | 65,000 | 1,431 | 0.07% | 0.07% | 49 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| ALLIANCEBERNSTEIN L.P. | History | No change | 61,090 | 1,345 | 0.0% | 0.0% | 50 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| CITIGROUP INC | History | Added to | 112,403 | 1,283 | 0.0% | 0.0% | 51 | +90,856 | 421.66% | Q3 2026 | Nov 04, 2026 |
| MORGAN STANLEY | History | No change | 57,786 | 1,273 | 0.0% | 0.0% | 52 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| BANK OF AMERICA CORP /DE/ | History | No change | 56,510 | 1,244 | 0.0% | 0.0% | 53 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| BARCLAYS PLC | History | Added to | 101,280 | 1,156 | 0.0% | 0.0% | 54 | +90,949 | 880.35% | Q3 2026 | Nov 06, 2026 |
| XTX Topco Ltd | History | No change | 49,224 | 1,084 | 0.01% | 0.01% | 55 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| LAZARD ASSET MANAGEMENT LLC | History | No change | 48,391 | 1,066 | 0.0% | 0.0% | 56 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| TUDOR INVESTMENT CORP ET AL | History | No change | 48,050 | 1,058 | 0.0% | 0.0% | 57 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| WELLS FARGO & COMPANY/MN | History | No change | 43,120 | 949 | 0.0% | 0.0% | 58 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| LOS ANGELES CAPITAL MANAGEMENT LLC | History | New | 74,803 | 854 | 0.0% | — | 59 | +74,803 | New | Q3 2026 | Nov 12, 2026 |
| Foresite Capital Management VI LLC | History | No change | 37,500 | 826 | 0.13% | 0.13% | 60 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Swiss National Bank | History | New | 72,000 | 822 | 0.0% | — | 61 | +72,000 | New | Q3 2026 | Nov 12, 2026 |
| Y-Intercept (Hong Kong) Ltd | History | New | 69,168 | 789 | 0.02% | — | 62 | +69,168 | New | Q3 2026 | Oct 16, 2026 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | History | No change | 32,609 | 718 | 0.0% | 0.0% | 63 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Mirador Capital Partners LP | History | New | 58,284 | 665 | 0.08% | — | 64 | +58,284 | New | Q3 2026 | Oct 09, 2026 |
| RHUMBLINE ADVISERS | History | Reduced | 57,160 | 652 | 0.0% | 0.0% | 65 | -1,227 | -2.1% | Q3 2026 | Nov 10, 2026 |
| AXQ CAPITAL, LP | History | New | 56,864 | 649 | 0.08% | — | 66 | +56,864 | New | Q3 2026 | Nov 12, 2026 |
| Invesco Ltd. | History | No change | 28,389 | 625 | 0.0% | 0.0% | 67 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| MetLife Investment Management, LLC | History | No change | 27,326 | 601 | 0.0% | 0.0% | 68 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| PRAXIS INVESTMENT MANAGEMENT INC | History | New | 51,340 | 586 | 0.03% | — | 69 | +51,340 | New | Q3 2026 | Nov 03, 2026 |
| DEUTSCHE BANK AG\ | History | Reduced | 41,472 | 473 | 0.0% | 0.0% | 70 | -4,176 | -9.15% | Q3 2026 | Nov 06, 2026 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | History | No change | 21,171 | 466 | 0.0% | 0.0% | 71 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| JPMORGAN CHASE & CO | History | Added to | 38,970 | 456 | 0.0% | 0.0% | 72 | +7,662 | 24.47% | Q3 2026 | Nov 12, 2026 |
| SOROS FUND MANAGEMENT LLC | History | No change | 20,000 | 440 | 0.01% | 0.01% | 73 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| CIBC WORLD MARKET INC. | History | Added to | 37,181 | 424 | 0.0% | 0.0% | 74 | +1,705 | 4.81% | Q3 2026 | Nov 10, 2026 |
| Quadrature Capital Ltd | History | No change | 19,200 | 422 | 0.0% | 0.0% | 75 | 0 | 0.0% | Q2 2026 | Aug 06, 2026 |
| D. E. Shaw & Co., Inc. | History | No change | 17,500 | 385 | 0.0% | 0.0% | 76 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Vanguard Global Advisers, LLC | History | No change | 17,428 | 383 | 0.0% | 0.0% | 77 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| NEW YORK STATE COMMON RETIREMENT FUND | History | No change | 16,200 | 356 | 0.0% | 0.0% | 78 | 0 | 0.0% | Q2 2026 | Jul 29, 2026 |
| Tidal Investments LLC | History | No change | 14,039 | 309 | 0.0% | 0.0% | 79 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| Squarepoint Ops LLC | History | Reduced | 24,455 | 279 | 0.0% | 0.0% | 80 | -20,607 | -45.73% | Q3 2026 | Nov 09, 2026 |
| Hudson Bay Capital Management LP | History | No change | 10,050 | 221 | 0.0% | 0.0% | 81 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| GABELLI FUNDS LLC | History | No change | 10,000 | 220 | 0.0% | 0.0% | 82 | 0 | 0.0% | Q2 2026 | Aug 12, 2026 |
| PROFUND ADVISORS LLC | History | New | 18,880 | 215 | 0.01% | — | 83 | +18,880 | New | Q3 2026 | Oct 28, 2026 |
| Zurcher Kantonalbank (Zurich Cantonalbank) | History | New | 17,474 | 199 | 0.0% | — | 85 | +17,474 | New | Q3 2026 | Nov 10, 2026 |
| Legal & General Group Plc | History | No change | 9,048 | 199 | 0.0% | 0.0% | 84 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| TEMA ETFS LLC | History | Reduced | 13,945 | 159 | 0.01% | 0.01% | 86 | -94 | -0.67% | Q3 2026 | Oct 16, 2026 |
| Police & Firemen's Retirement System of New Jersey | History | No change | 13,618 | 155 | 0.0% | 0.0% | 87 | 0 | 0.0% | Q3 2026 | Nov 09, 2026 |
| LPL Financial LLC | History | New | 13,328 | 152 | 0.0% | — | 88 | +13,328 | New | Q3 2026 | Nov 06, 2026 |
| STRS OHIO | History | Added to | 12,600 | 143 | 0.0% | 0.0% | 89 | +3,600 | 40.0% | Q3 2026 | Oct 30, 2026 |
| COMMONWEALTH EQUITY SERVICES, LLC | History | New | 11,713 | 133 | 0.0% | — | 90 | +11,713 | New | Q3 2026 | Nov 02, 2026 |
| State of New Jersey Common Pension Fund D | History | New | 11,507 | 131 | 0.0% | — | 91 | +11,507 | New | Q3 2026 | Nov 05, 2026 |
| PRINCIPAL FINANCIAL GROUP INC | History | New | 10,636 | 121 | 0.0% | — | 92 | +10,636 | New | Q3 2026 | Nov 02, 2026 |
| Arizona State Retirement System | History | New | 10,054 | 114 | 0.0% | — | 93 | +10,054 | New | Q3 2026 | Nov 03, 2026 |
| Penserra Capital Management LLC | History | No change | 4,864 | 107 | 0.0% | 0.0% | 94 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| KLP KAPITALFORVALTNING AS | History | New | 8,200 | 93 | 0.0% | — | 95 | +8,200 | New | Q3 2026 | Nov 10, 2026 |
| Ameritas Investment Partners, Inc. | History | No change | 4,190 | 92 | 0.0% | 0.0% | 96 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| DIADEMA PARTNERS LP | History | No change | 3,621 | 79 | 0.01% | 0.01% | 97 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Tower Research Capital LLC (TRC) | History | No change | 3,289 | 72 | 0.0% | 0.0% | 98 | 0 | 0.0% | Q2 2026 | Aug 11, 2026 |
| US BANCORP \DE\ | History | Added to | 6,200 | 70 | 0.0% | 0.0% | 99 | +1,187 | 23.68% | Q3 2026 | Nov 05, 2026 |
| ROYAL BANK OF CANADA | History | No change | 2,924 | 65 | 0.0% | 0.0% | 100 | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| Russell Investments Group, Ltd. | History | Reduced | 3,673 | 41 | 0.0% | 0.0% | 101 | -49,644 | -93.11% | Q3 2026 | Nov 06, 2026 |
| Persistent Asset Partners Ltd | History | No change | 1,765 | 38 | 0.01% | 0.01% | 102 | 0 | 0.0% | Q2 2026 | Aug 06, 2026 |
| Federation des caisses Desjardins du Quebec | History | No change | 1,150 | 25 | 0.0% | 0.0% | 103 | 0 | 0.0% | Q2 2026 | Aug 13, 2026 |
| Sterling Capital Management LLC | History | Added to | 1,327 | 15 | 0.0% | 0.0% | 104 | +925 | 230.1% | Q3 2026 | Oct 22, 2026 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | History | No change | 636 | 14 | 0.0% | 0.0% | 105 | 0 | 0.0% | Q2 2026 | Aug 24, 2026 |
| Versant Capital Management, Inc | History | New | 1,186 | 13 | 0.0% | — | 106 | +1,186 | New | Q3 2026 | Oct 01, 2026 |
| NISA INVESTMENT ADVISORS, LLC | History | Added to | 1,055 | 12 | 0.0% | 0.0% | 107 | +184 | 21.13% | Q3 2026 | Oct 20, 2026 |
| Caitong International Asset Management Co., Ltd | History | Added to | 957 | 10 | 0.0% | — | 108 | +937 | 4685.0% | Q3 2026 | Oct 29, 2026 |
| Parallel Advisors, LLC | History | New | 900 | 10 | 0.0% | — | 109 | +900 | New | Q3 2026 | Nov 03, 2026 |
| Arax Advisory Partners | History | New | 640 | 7 | 0.0% | — | 110 | +640 | New | Q3 2026 | Nov 12, 2026 |
| Global Retirement Partners, LLC | History | New | 546 | 6 | 0.0% | — | 111 | +546 | New | Q3 2026 | Nov 10, 2026 |
| PNC FINANCIAL SERVICES GROUP, INC. | History | Reduced | 235 | 2 | 0.0% | 0.0% | 112 | -2,407 | -91.11% | Q3 2026 | Nov 06, 2026 |
| Farther Finance Advisors, LLC | History | New | 90 | 1 | 0.0% | — | 114 | +90 | New | Q3 2026 | Oct 08, 2026 |
| EverSource Wealth Advisors, LLC | History | New | 88 | 1 | 0.0% | — | 113 | +88 | New | Q3 2026 | Nov 04, 2026 |
| Universal- Beteiligungs- und Servicegesellschaft mbH | History | Closed out | 0 | 0 | — | 0.0% | — | -22,951 | -100.0% | Q3 2026 | Nov 10, 2026 |
| Harbour Capital Advisors, LLC | History | Closed out | 0 | 0 | — | 0.06% | — | -16,570 | -100.0% | Q3 2026 | Oct 13, 2026 |
| VICTORY CAPITAL MANAGEMENT INC | History | Closed out | 0 | 0 | — | 0.0% | — | -10,306 | -100.0% | Q3 2026 | Nov 10, 2026 |
| IFP Advisors, Inc | History | New | 48 | 0 | — | — | — | +48 | New | Q3 2026 | Oct 16, 2026 |
| GAMMA Investing LLC | History | New | 34 | 0 | — | — | — | +34 | New | Q3 2026 | Oct 08, 2026 |
| Fortitude Family Office, LLC | History | Closed out | 0 | 0 | — | — | — | -32 | -100.0% | Q3 2026 | Oct 14, 2026 |
| Covestor Ltd | History | New | 18 | 0 | — | — | — | +18 | New | Q3 2026 | Oct 30, 2026 |
| Clearstead Advisors, LLC | History | New | 13 | 0 | — | — | — | +13 | New | Q3 2026 | Nov 06, 2026 |
| SJS Investment Consulting Inc. | History | New | 7 | 0 | — | — | — | +7 | New | Q3 2026 | Oct 26, 2026 |
| ROTHSCHILD INVESTMENT LLC | History | New | 5 | 0 | — | — | — | +5 | New | Q3 2026 | Nov 10, 2026 |
| JONES FINANCIAL COMPANIES LLLP | History | No change | 15 | 0 | — | — | — | 0 | 0.0% | Q2 2026 | Aug 14, 2026 |
| SBI Securities Co., Ltd. | History | No change | 1 | 0 | — | — | — | 0 | 0.0% | Q3 2026 | Oct 21, 2026 |