CytomX Therapeutics, Inc. - CTMX

Detailed investor-level table based on 13F positions.
Early Q1 2026 data: only 13 institutional holders reported so far. The full shareholder list will grow as more funds file with the SEC.

Shareholders (13F)

Quarter: Q4 2025 · Compare: Q3 2025
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
FMR LLC History Added to 24,688,109 105,171 0.01% 0.0% 1 +9,291,909 60.35% Q4 2025 Feb 17, 2026
VR Adviser, LLC History No change 15,561,500 66,291 3.27% 2.79% 2 0 0.0% Q4 2025 Feb 17, 2026
PERCEPTIVE ADVISORS LLC History No change 9,680,185 41,237 0.74% 0.89% 3 0 0.0% Q4 2025 Feb 17, 2026
Kynam Capital Management, LP History Added to 8,966,077 38,195 2.44% 0.87% 4 +5,319,574 145.88% Q4 2025 Feb 17, 2026
VANGUARD GROUP INC History Reduced 8,475,584 36,105 0.0% 0.0% 5 -472,223 -5.28% Q4 2025 Jan 29, 2026
Commodore Capital LP History No change 7,692,300 32,769 2.18% 1.2% 6 0 0.0% Q4 2025 Feb 17, 2026
Point72 Asset Management, L.P. History Added to 5,189,538 22,107 0.02% 0.02% 7 +1,120,963 27.55% Q4 2025 Feb 17, 2026
STATE STREET CORP History Added to 5,140,931 21,900 0.0% 0.0% 8 +4,495,949 697.07% Q4 2025 Feb 13, 2026
BALYASNY ASSET MANAGEMENT L.P. History Reduced 4,772,202 20,329 0.03% 0.02% 9 -40,879 -0.85% Q4 2025 Feb 17, 2026
ADAR1 Capital Management, LLC History Added to 4,282,769 18,244 1.34% 1.21% 10 +237,355 5.87% Q4 2025 Feb 18, 2026
BAKER BROS. ADVISORS LP History No change 4,250,826 18,108 0.11% 0.1% 11 0 0.0% Q4 2025 Feb 17, 2026
Financial Engines Advisors L.L.C. History Added to 3,828,717 16,310 0.03% 0.01% 12 +2,447,360 177.17% Q4 2025 Feb 12, 2026
BlackRock, Inc. History Added to 3,669,393 15,631 0.0% 0.0% 13 +1,287,481 54.05% Q4 2025 Feb 12, 2026
ORBIMED ADVISORS LLC History Reduced 3,525,650 15,019 0.31% 0.63% 14 -4,935,850 -58.33% Q4 2025 Feb 17, 2026
Ikarian Capital, LLC History Reduced 3,172,616 13,515 1.06% 1.09% 15 -200,000 -5.93% Q4 2025 Feb 18, 2026
Vivo Capital, LLC History No change 2,884,615 12,288 0.79% 0.74% 16 0 0.0% Q4 2025 Feb 13, 2026
Eversept Partners, LP History New 2,507,090 10,680 0.54% 17 +2,507,090 New Q4 2025 Feb 17, 2026
GOLDMAN SACHS GROUP INC History Added to 2,460,944 10,483 0.0% 0.0% 18 +2,013,191 449.62% Q4 2025 Mar 25, 2026
Woodline Partners LP History No change 2,337,005 9,955 0.04% 0.04% 19 0 0.0% Q4 2025 Feb 17, 2026
TWO SIGMA INVESTMENTS, LP History Added to 1,560,755 6,648 0.01% 0.0% 20 +831,057 113.89% Q4 2025 Feb 17, 2026
GEODE CAPITAL MANAGEMENT, LLC History Reduced 1,525,666 6,502 0.0% 0.0% 21 -43,632 -2.78% Q4 2025 Feb 09, 2026
DIMENSIONAL FUND ADVISORS LP History Added to 1,289,656 5,492 0.0% 0.0% 22 +838,528 185.87% Q4 2025 Feb 12, 2026
MARSHALL WACE, LLP History Added to 1,156,936 4,928 0.0% 0.0% 23 +51,943 4.7% Q4 2025 Feb 13, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History Added to 1,080,098 4,601 0.0% 0.0% 24 +446,813 70.55% Q4 2025 Feb 17, 2026
Qube Research & Technologies Ltd History Added to 1,061,128 4,520 0.0% 0.0% 25 +938,628 766.23% Q4 2025 Feb 17, 2026
STEMPOINT CAPITAL LP History New 1,036,311 4,414 0.76% 26 +1,036,311 New Q4 2025 Feb 17, 2026
BOOTHBAY FUND MANAGEMENT, LLC History Reduced 894,663 3,811 0.06% 0.06% 27 -342,394 -27.68% Q4 2025 Feb 17, 2026
BANK OF AMERICA CORP /DE/ History Reduced 876,305 3,733 0.0% 0.0% 28 -128,923 -12.83% Q4 2025 Feb 17, 2026
ACADIAN ASSET MANAGEMENT LLC History Added to 856,056 3,644 0.01% 0.0% 29 +202,331 30.95% Q4 2025 Feb 10, 2026
Exome Asset Management LLC History No change 745,305 3,174 1.52% 1.44% 30 0 0.0% Q4 2025 Feb 13, 2026
Elmind Capital, LP History New 700,000 2,982 0.88% 31 +700,000 New Q4 2025 Feb 17, 2026
JANE STREET GROUP, LLC History Added to 697,018 2,969 0.0% 0.0% 32 +241,651 53.07% Q4 2025 Feb 12, 2026
Assenagon Asset Management S.A. History Reduced 592,696 2,524 0.0% 0.0% 33 -137,271 -18.81% Q4 2025 Jan 09, 2026
CITADEL ADVISORS LLC History Reduced 472,804 2,014 0.0% 0.0% 34 -1,505,631 -76.1% Q4 2025 Feb 17, 2026
FIRST TRUST ADVISORS LP History Added to 423,168 1,802 0.0% 0.0% 35 +21,277 5.29% Q4 2025 Feb 13, 2026
NORTHERN TRUST CORP History Added to 415,178 1,768 0.0% 0.0% 36 +25,493 6.54% Q4 2025 Feb 17, 2026
MORGAN STANLEY History Added to 401,191 1,709 0.0% 0.0% 37 +81,903 25.65% Q4 2025 Feb 13, 2026
SILVERARC CAPITAL MANAGEMENT, LLC History New 385,974 1,644 0.23% 38 +385,974 New Q4 2025 Feb 12, 2026
SCHULHOFF & CO INC History New 374,850 1,596 0.67% 39 +374,850 New Q4 2025 Feb 11, 2026
UBS Group AG History Added to 370,739 1,579 0.0% 0.0% 40 +340,571 1128.91% Q4 2025 Jan 29, 2026
BARCLAYS PLC History Added to 336,525 1,433 0.0% 0.0% 41 +335,035 22485.57% Q4 2025 Feb 13, 2026
TWO SIGMA ADVISERS, LP History Added to 335,524 1,429 0.0% 0.0% 42 +295,524 738.81% Q4 2025 Feb 17, 2026
Bank of New York Mellon Corp History Added to 328,248 1,398 0.0% 0.0% 43 +75,589 29.92% Q4 2025 Feb 10, 2026
RAYMOND JAMES FINANCIAL INC History Added to 316,971 1,350 0.0% 0.0% 44 +23,411 7.97% Q4 2025 Feb 18, 2026
MILLENNIUM MANAGEMENT LLC History Reduced 289,653 1,233 0.0% 0.0% 45 -1,097,210 -79.11% Q4 2025 Feb 17, 2026
Rafferty Asset Management, LLC History New 273,584 1,165 0.0% 46 +273,584 New Q4 2025 Feb 13, 2026
AMERIPRISE FINANCIAL INC History Added to 229,599 988 0.0% 0.0% 47 +71,270 45.01% Q4 2025 Feb 17, 2026
PRELUDE CAPITAL MANAGEMENT, LLC History No change 206,526 879 0.06% 0.05% 48 0 0.0% Q4 2025 Feb 17, 2026
Informed Momentum Co LLC History New 203,823 868 0.1% 49 +203,823 New Q4 2025 Feb 12, 2026
HighVista Strategies LLC History Reduced 193,941 826 0.21% 0.2% 50 -63,207 -24.58% Q4 2025 Feb 17, 2026
SEI INVESTMENTS CO History New 124,124 528 0.0% 51 +124,124 New Q4 2025 Feb 13, 2026
LPL Financial LLC History Added to 113,440 483 0.0% 0.0% 52 +26,787 30.91% Q4 2025 Feb 11, 2026
CANADA PENSION PLAN INVESTMENT BOARD History New 104,200 443 0.0% 53 +104,200 New Q4 2025 Feb 17, 2026
Aspire Growth Partners LLC History No change 102,254 435 0.3% 0.24% 54 0 0.0% Q4 2025 Feb 05, 2026
NLB Skladi, upravljanje premozenja, d.o.o. History New 100,000 426 0.02% 55 +100,000 New Q4 2025 Feb 13, 2026
PROFUND ADVISORS LLC History New 98,633 420 0.01% 56 +98,633 New Q4 2025 Feb 06, 2026
CITIGROUP INC History Added to 96,326 410 0.0% 0.0% 57 +88,570 1141.95% Q4 2025 Feb 13, 2026
OMERS ADMINISTRATION Corp History New 87,800 374 0.0% 58 +87,800 New Q4 2025 Feb 13, 2026
GSA CAPITAL PARTNERS LLP History Reduced 81,886 349 0.03% 0.14% 59 -454,088 -84.72% Q4 2025 Feb 06, 2026
Velan Capital Investment Management LP History No change 80,000 340 0.2% 0.24% 60 0 0.0% Q4 2025 Feb 13, 2026
HRT FINANCIAL LP History New 71,867 306 0.0% 61 +71,867 New Q4 2025 Feb 12, 2026
CHARLES SCHWAB INVESTMENT MANAGEMENT INC History Reduced 68,687 292 0.0% 0.0% 62 -19,883 -22.45% Q4 2025 Feb 13, 2026
Miller Financial Services LLC History Added to 68,000 289 0.34% 0.25% 63 +1,000 1.49% Q4 2025 Feb 12, 2026
Virtus Investment Advisers, LLC History New 63,491 270 0.07% 64 +63,491 New Q4 2025 Feb 17, 2026
Brooklyn Investment Group History New 61,474 257 0.01% 65 +61,474 New Q4 2025 Feb 12, 2026
Congress Park Capital LLC History Reduced 58,922 251 0.07% 0.1% 66 -45,000 -43.3% Q4 2025 Jan 14, 2026
SG Americas Securities, LLC History New 53,109 226 0.0% 67 +53,109 New Q4 2025 Jan 09, 2026
Merit Financial Group, LLC History No change 53,243 226 0.0% 0.0% 68 0 0.0% Q4 2025 Jan 26, 2026
Hudson Bay Capital Management LP History New 50,990 217 0.0% 69 +50,990 New Q4 2025 Feb 13, 2026
Squarepoint Ops LLC History Added to 49,897 212 0.0% 0.0% 70 +2,169 4.54% Q4 2025 Feb 13, 2026
Seven Fleet Capital Management LP History New 48,898 208 0.14% 71 +48,898 New Q4 2025 Apr 02, 2026
XTX Topco Ltd History Added to 47,991 204 0.01% 0.0% 72 +18,705 63.87% Q4 2025 Feb 17, 2026
Susquehanna Portfolio Strategies, LLC History No change 48,012 204 0.0% 0.0% 73 0 0.0% Q4 2025 Feb 17, 2026
Formidable Asset Management, LLC History Reduced 45,763 194 0.03% 0.06% 74 -72,574 -61.33% Q4 2025 Jan 16, 2026
Tidal Investments LLC History Reduced 45,763 194 0.0% 0.0% 75 -72,574 -61.33% Q4 2025 Feb 13, 2026
Baader Bank Aktiengesellschaft History New 45,000 191 0.01% 76 +45,000 New Q4 2025 Feb 05, 2026
Private Advisor Group, LLC History No change 44,002 187 0.0% 0.0% 77 0 0.0% Q4 2025 Feb 17, 2026
J. Goldman & Co LP History New 37,000 157 0.0% 78 +37,000 New Q4 2025 Feb 17, 2026
Lighthouse Investment Partners, LLC History New 32,040 136 0.0% 79 +32,040 New Q4 2025 Feb 17, 2026
Cambria Investment Management, L.P. History New 31,332 133 0.01% 80 +31,332 New Q4 2025 Feb 17, 2026
Empowered Funds, LLC History New 31,332 133 0.0% 81 +31,332 New Q4 2025 Feb 18, 2026
China Universal Asset Management Co., Ltd. History New 27,609 117 0.01% 82 +27,609 New Q4 2025 Jan 29, 2026
Truvestments Capital LLC History Added to 27,428 116 0.02% 0.01% 83 +10,327 60.39% Q4 2025 Feb 13, 2026
Vanguard Personalized Indexing Management, LLC History Reduced 26,765 114 0.0% 0.0% 84 -174 -0.65% Q4 2025 Feb 13, 2026
Engineers Gate Manager LP History New 26,539 113 0.0% 85 +26,539 New Q4 2025 Feb 17, 2026
MANGROVE PARTNERS IM, LLC History New 26,265 111 0.01% 86 +26,265 New Q4 2025 Feb 17, 2026
HB Wealth Management, LLC History New 25,000 106 0.0% 87 +25,000 New Q4 2025 Jan 28, 2026
Tower Research Capital LLC (TRC) History Added to 24,794 105 0.0% 88 +24,791 826366.67% Q4 2025 Feb 17, 2026
JPMORGAN CHASE & CO History Added to 24,363 103 0.0% 0.0% 89 +8,211 50.84% Q4 2025 Feb 11, 2026
SIMPLEX TRADING, LLC History New 24,051 102 0.0% 90 +24,051 New Q4 2025 Feb 11, 2026
Jefferies Financial Group Inc. History Reduced 23,764 101 0.0% 0.0% 91 -29,150 -55.09% Q4 2025 Feb 09, 2026
Ethos Financial Group, LLC History No change 23,697 100 0.01% 0.01% 92 0 0.0% Q4 2025 Jan 20, 2026
Mariner, LLC History Added to 22,180 94 0.0% 0.0% 93 +11,930 116.39% Q4 2025 Feb 13, 2026
Invesco Ltd. History Reduced 21,976 93 0.0% 0.0% 94 -450 -2.01% Q4 2025 Feb 19, 2026
State of Wyoming History New 21,511 91 0.01% 95 +21,511 New Q4 2025 Feb 11, 2026
Jain Global LLC History Reduced 21,212 90 0.0% 0.0% 96 -12,440 -36.97% Q4 2025 Feb 17, 2026
OSAIC HOLDINGS, INC. History Added to 19,410 82 0.0% 0.0% 97 +2,700 16.16% Q4 2025 Feb 17, 2026
Sanctuary Advisors, LLC History New 19,140 81 0.0% 98 +19,140 New Q4 2025 Jan 29, 2026
Forefront Analytics, LLC History Added to 18,699 79 0.07% 0.05% 99 +590 3.26% Q4 2025 Feb 17, 2026
TWINBEECH CAPITAL LP History New 17,600 74 0.01% 100 +17,600 New Q4 2025 Feb 17, 2026
WestHill Financial Advisors, Inc. History No change 17,082 72 0.01% 0.01% 101 0 0.0% Q4 2025 Jan 21, 2026
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. History New 15,959 66 0.0% 102 +15,959 New Q4 2025 Feb 17, 2026
EVOLVE PRIVATE WEALTH, LLC History New 14,834 63 0.0% 104 +14,834 New Q4 2025 Feb 17, 2026
PACES FERRY WEALTH ADVISORS, LLC History New 14,822 63 0.03% 103 +14,822 New Q4 2025 Feb 11, 2026
VICTORY CAPITAL MANAGEMENT INC History Added to 14,722 62 0.0% 0.0% 105 +601 4.26% Q4 2025 Feb 13, 2026
PURSUE WEALTH PARTNERS LLC History No change 14,492 62 0.03% 0.03% 106 0 0.0% Q4 2025 Jan 26, 2026
BANK OF NOVA SCOTIA History New 13,661 58 0.0% 107 +13,661 New Q4 2025 Feb 13, 2026
Nierenberg Investment Management Company, LLC History No change 12,555 53 0.03% 0.02% 108 0 0.0% Q4 2025 Feb 13, 2026
IPG Investment Advisors LLC History No change 12,500 53 0.01% 0.01% 109 0 0.0% Q4 2025 Feb 09, 2026
HSBC HOLDINGS PLC History New 12,230 52 0.0% 110 +12,230 New Q4 2025 Mar 20, 2026
Brevan Howard Capital Management LP History New 11,404 48 0.0% 111 +11,404 New Q4 2025 Feb 17, 2026
May Hill Capital, LLC History New 10,856 46 0.01% 112 +10,856 New Q4 2025 Feb 05, 2026
Peregrine Asset Advisers, Inc. History No change 10,000 42 0.01% 0.01% 113 0 0.0% Q4 2025 Feb 02, 2026
Caitong International Asset Management Co., Ltd History Added to 9,380 39 0.01% 0.0% 114 +8,691 1261.39% Q4 2025 Mar 03, 2026
Mirae Asset Global Investments Co., Ltd. History New 8,233 35 0.0% 115 +8,233 New Q4 2025 Jan 26, 2026
Farther Finance Advisors, LLC History Reduced 7,875 33 0.0% 0.0% 116 -95 -1.19% Q4 2025 Jan 23, 2026
WELLS FARGO & COMPANY/MN History Added to 6,605 28 0.0% 0.0% 117 +3,000 83.22% Q4 2025 Feb 13, 2026
GF FUND MANAGEMENT CO. LTD. History New 3,329 14 0.0% 118 +3,329 New Q4 2025 Jan 27, 2026
BNP PARIBAS FINANCIAL MARKETS History Added to 2,825 12 0.0% 119 +2,808 16517.65% Q4 2025 Feb 10, 2026
Daiwa Securities Group Inc. History New 564 2 0.0% 120 +564 New Q4 2025 Feb 11, 2026
ROYAL BANK OF CANADA History New 214 1 0.0% 121 +214 New Q4 2025 Feb 17, 2026
TANG CAPITAL MANAGEMENT LLC History Closed out 0 0 1.36% -11,065,662 -100.0% Q3 2025 Nov 14, 2025
RA CAPITAL MANAGEMENT, L.P. History Closed out 0 0 0.1% -2,661,331 -100.0% Q3 2025 Nov 14, 2025
RENAISSANCE TECHNOLOGIES LLC History Closed out 0 0 0.01% -2,545,260 -100.0% Q3 2025 Nov 13, 2025
Prosight Management, LP History Closed out 0 0 0.42% -564,800 -100.0% Q3 2025 Nov 14, 2025
Inspire Investing, LLC History Reduced 8 0 0.16% -522,474 -100.0% Q4 2025 Feb 17, 2026
Caption Management, LLC History Closed out 0 0 0.01% -249,900 -100.0% Q3 2025 Nov 14, 2025
Precision Wealth Strategies, LLC History Closed out 0 0 0.25% -237,081 -100.0% Q3 2025 Oct 16, 2025
DIADEMA PARTNERS LP History Closed out 0 0 0.15% -185,286 -100.0% Q3 2025 Nov 14, 2025
Quadrature Capital Ltd History Closed out 0 0 0.0% -125,035 -100.0% Q3 2025 Nov 13, 2025
Stonepine Capital Management, LLC History Closed out 0 0 0.32% -125,000 -100.0% Q3 2025 Nov 13, 2025
Persistent Asset Partners Ltd History Closed out 0 0 0.09% -42,645 -100.0% Q3 2025 Jan 15, 2026
PRUDENTIAL FINANCIAL INC History Closed out 0 0 0.0% -23,300 -100.0% Q3 2025 Nov 13, 2025
BlueChip Wealth Advisors LLC History Closed out 0 0 0.03% -23,000 -100.0% Q3 2025 Nov 06, 2025
Forefront Wealth Partners, LLC History Closed out 0 0 0.01% -18,109 -100.0% Q3 2025 Oct 20, 2025
BIT Capital GmbH History Closed out 0 0 0.0% -16,285 -100.0% Q3 2025 Nov 10, 2025
TRUIST FINANCIAL CORP History Closed out 0 0 0.0% -12,500 -100.0% Q3 2025 Nov 03, 2025
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors History Closed out 0 0 0.0% -10,747 -100.0% Q3 2025 Oct 24, 2025
Meridian Wealth Management, LLC History Closed out 0 0 0.0% -10,000 -100.0% Q3 2025 Nov 04, 2025
Private Wealth Asset Management, LLC History Closed out 0 0 0.0% -4,000 -100.0% Q3 2025 Nov 03, 2025
Advisory Services Network, LLC History Closed out 0 0 -274 -100.0% Q3 2025 Nov 18, 2025
SBI Securities Co., Ltd. History Reduced 28 0 -57 -67.06% Q4 2025 Feb 03, 2026