Lexeo Therapeutics, Inc. - LXEO

Detailed investor-level table based on 13F positions.
Early Q1 2026 data: only 8 institutional holders reported so far. The full shareholder list will grow as more funds file with the SEC.

Shareholders (13F)

Quarter: Q4 2025 · Compare: Q3 2025
13D/13G major owners: Ownership tab.
Methodology: Market value and % of portfolio use SEC reported VALUE ($000). For PUT/CALL positions this reflects reported underlying exposure, not premium cash paid/received. Details.
Rows: 0
Investor History Status Shares held Market value ($000) % of portfolio Previous % Rank Change in shares % change in shares Source Date reported
CAXTON CORP History Reduced 13,943 138,453 3.24% 0.5% 1 -3,389 -19.55% Q4 2025 Feb 13, 2026
JANUS HENDERSON GROUP PLC History Reduced 5,509,635 54,668 0.02% 0.02% 2 -595,892 -9.76% Q4 2025 Feb 17, 2026
RA CAPITAL MANAGEMENT, L.P. History New 5,000,000 49,650 0.51% 3 +5,000,000 New Q4 2025 Feb 17, 2026
BlackRock, Inc. History Added to 4,907,563 48,732 0.0% 0.0% 4 +2,736,471 126.04% Q4 2025 Feb 12, 2026
Paradigm Biocapital Advisors LP History New 4,763,198 47,298 1.21% 5 +4,763,198 New Q4 2025 Feb 17, 2026
Vestal Point Capital, LP History Added to 4,475,000 44,436 1.51% 0.97% 6 +1,225,000 37.69% Q4 2025 Feb 17, 2026
Frazier Life Sciences Management, L.P. History No change 4,424,725 43,937 1.18% 0.88% 7 0 0.0% Q4 2025 Feb 13, 2026
VANGUARD GROUP INC History Added to 3,894,310 38,670 0.0% 0.0% 8 +1,668,020 74.92% Q4 2025 Jan 29, 2026
CITADEL ADVISORS LLC History Added to 3,774,317 37,478 0.01% 0.0% 9 +55,274 1.49% Q4 2025 Feb 17, 2026
Avoro Capital Advisors LLC History New 3,300,000 32,769 0.32% 10 +3,300,000 New Q4 2025 Mar 13, 2026
Affinity Asset Advisors, LLC History Reduced 3,200,000 31,776 1.81% 2.24% 11 -670,527 -17.32% Q4 2025 Feb 13, 2026
Woodline Partners LP History Added to 3,197,760 31,753 0.12% 0.08% 12 +625,598 24.32% Q4 2025 Feb 17, 2026
STATE STREET CORP History Added to 3,187,722 31,654 0.0% 0.0% 13 +2,642,877 485.07% Q4 2025 Feb 13, 2026
ORBIMED ADVISORS LLC History New 2,125,000 21,101 0.43% 14 +2,125,000 New Q4 2025 Feb 17, 2026
Point72 Asset Management, L.P. History Reduced 1,894,722 18,814 0.02% 0.02% 15 -47,127 -2.43% Q4 2025 Feb 17, 2026
Octagon Capital Advisors LP History New 1,725,000 17,129 2.08% 16 +1,725,000 New Q4 2025 Feb 17, 2026
BALYASNY ASSET MANAGEMENT L.P. History Reduced 1,635,026 16,235 0.02% 0.03% 17 -2,278,762 -58.22% Q4 2025 Feb 17, 2026
GEODE CAPITAL MANAGEMENT, LLC History Added to 1,445,887 14,361 0.0% 0.0% 18 +724,006 100.29% Q4 2025 Feb 09, 2026
ADAR1 Capital Management, LLC History Reduced 1,393,161 13,834 1.02% 0.96% 19 -138,792 -9.06% Q4 2025 Feb 18, 2026
SUVRETTA CAPITAL MANAGEMENT, LLC History New 1,250,000 12,412 0.25% 20 +1,250,000 New Q4 2025 Feb 17, 2026
683 Capital Management, LLC History Added to 1,120,000 11,121 0.48% 0.32% 21 +197,338 21.39% Q4 2025 Feb 17, 2026
Nantahala Capital Management, LLC History New 1,000,000 9,930 0.33% 22 +1,000,000 New Q4 2025 Feb 13, 2026
MILLENNIUM MANAGEMENT LLC History Reduced 908,024 9,016 0.0% 0.01% 23 -1,405,618 -60.75% Q4 2025 Feb 17, 2026
Blackstone Inc. History Reduced 904,959 8,986 0.04% 0.03% 24 -219,963 -19.55% Q4 2025 Feb 17, 2026
DIMENSIONAL FUND ADVISORS LP History Reduced 862,892 8,567 0.0% 0.0% 25 -49,641 -5.44% Q4 2025 Feb 12, 2026
GOLDMAN SACHS GROUP INC History Added to 781,855 7,763 0.0% 0.0% 26 +639,453 449.05% Q4 2025 Mar 25, 2026
Siren, L.L.C. History Added to 720,622 7,155 0.21% 0.16% 27 +117,187 19.42% Q4 2025 Feb 13, 2026
SILVERARC CAPITAL MANAGEMENT, LLC History Reduced 617,608 6,132 0.85% 0.7% 28 -161,003 -20.68% Q4 2025 Feb 12, 2026
Ikarian Capital, LLC History Reduced 513,011 5,094 0.4% 0.38% 29 -54,590 -9.62% Q4 2025 Feb 18, 2026
D. E. Shaw & Co., Inc. History Added to 480,205 4,768 0.0% 0.0% 30 +467,387 3646.33% Q4 2025 Feb 17, 2026
Invesco Ltd. History New 463,029 4,597 0.0% 31 +463,029 New Q4 2025 Feb 19, 2026
NORTHERN TRUST CORP History Added to 457,052 4,538 0.0% 0.0% 32 +220,599 93.3% Q4 2025 Feb 17, 2026
Verition Fund Management LLC History Added to 428,458 4,254 0.02% 0.01% 33 +13,595 3.28% Q4 2025 Feb 13, 2026
TWO SIGMA INVESTMENTS, LP History Added to 400,567 3,977 0.01% 0.0% 34 +315,804 372.57% Q4 2025 Feb 17, 2026
DAFNA Capital Management LLC History Reduced 340,859 3,384 0.79% 0.59% 35 -17,224 -4.81% Q4 2025 Feb 17, 2026
AQR CAPITAL MANAGEMENT LLC History Reduced 337,386 3,350 0.0% 0.0% 36 -10,537 -3.03% Q4 2025 Feb 17, 2026
UBS Group AG History Added to 281,083 2,791 0.0% 0.0% 37 +31,174 12.47% Q4 2025 Jan 29, 2026
BNP PARIBAS FINANCIAL MARKETS History Added to 257,417 2,556 0.0% 0.0% 38 +226,690 737.76% Q4 2025 Feb 10, 2026
AMERIPRISE FINANCIAL INC History Added to 243,294 2,415 0.0% 0.0% 39 +76,756 46.09% Q4 2025 Feb 17, 2026
Y-Intercept (Hong Kong) Ltd History New 231,163 2,295 0.05% 40 +231,163 New Q4 2025 Feb 13, 2026
RENAISSANCE TECHNOLOGIES LLC History Added to 217,772 2,162 0.0% 0.0% 41 +68,472 45.86% Q4 2025 Feb 12, 2026
Nuveen, LLC History Added to 211,529 2,100 0.0% 0.0% 42 +178,427 539.02% Q4 2025 Feb 12, 2026
Privium Fund Management B.V. History Added to 192,550 1,912 0.35% 0.23% 43 +194 0.1% Q4 2025 Feb 03, 2026
CHARLES SCHWAB INVESTMENT MANAGEMENT INC History Added to 192,210 1,908 0.0% 0.0% 44 +86,450 81.74% Q4 2025 Feb 13, 2026
BARCLAYS PLC History Added to 188,754 1,874 0.0% 0.0% 45 +77,175 69.17% Q4 2025 Feb 13, 2026
Spruce Street Capital LP History New 175,000 1,737 0.57% 46 +175,000 New Q4 2025 Feb 13, 2026
Bank of New York Mellon Corp History Added to 166,749 1,655 0.0% 0.0% 47 +95,072 132.64% Q4 2025 Feb 10, 2026
BANK OF AMERICA CORP /DE/ History Added to 160,288 1,591 0.0% 0.0% 48 +132,009 466.81% Q4 2025 Feb 17, 2026
MORGAN STANLEY History Added to 140,181 1,391 0.0% 0.0% 49 +42,124 42.96% Q4 2025 Feb 13, 2026
JANE STREET GROUP, LLC History Added to 140,096 1,391 0.0% 0.0% 50 +10,624 8.21% Q4 2025 Feb 12, 2026
PERCEPTIVE ADVISORS LLC History No change 139,835 1,388 0.02% 0.03% 51 0 0.0% Q4 2025 Feb 17, 2026
BOOTHBAY FUND MANAGEMENT, LLC History Reduced 136,377 1,354 0.02% 0.02% 52 -44,367 -24.55% Q4 2025 Feb 17, 2026
Qube Research & Technologies Ltd History New 133,257 1,323 0.0% 53 +133,257 New Q4 2025 Feb 17, 2026
Burkehill Global Management, LP History New 125,000 1,241 0.08% 54 +125,000 New Q4 2025 Feb 17, 2026
Rafferty Asset Management, LLC History New 102,159 1,014 0.0% 55 +102,159 New Q4 2025 Feb 13, 2026
Squarepoint Ops LLC History New 92,608 919 0.0% 56 +92,608 New Q4 2025 Feb 13, 2026
WELLINGTON MANAGEMENT GROUP LLP History New 83,230 826 0.0% 57 +83,230 New Q4 2025 Feb 17, 2026
TWO SIGMA ADVISERS, LP History New 81,300 807 0.0% 58 +81,300 New Q4 2025 Feb 17, 2026
WELLS FARGO & COMPANY/MN History Added to 70,736 702 0.0% 0.0% 59 +51,474 267.23% Q4 2025 Feb 13, 2026
RHUMBLINE ADVISERS History Added to 69,369 688 0.0% 0.0% 60 +37,605 118.39% Q4 2025 Feb 13, 2026
Atom Investors LP History New 68,491 680 0.05% 61 +68,491 New Q4 2025 Feb 17, 2026
ALLIANCEBERNSTEIN L.P. History Added to 61,810 613 0.0% 0.0% 62 +32,440 110.45% Q4 2025 Feb 17, 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP History Added to 61,309 608 0.0% 0.0% 63 +19,478 46.56% Q4 2025 Feb 17, 2026
DEUTSCHE BANK AG\ History Added to 57,166 567 0.0% 0.0% 64 +32,844 135.04% Q4 2025 Feb 11, 2026
ACADIAN ASSET MANAGEMENT LLC History New 50,909 505 0.0% 65 +50,909 New Q4 2025 Feb 10, 2026
AMERICAN CENTURY COMPANIES INC History Added to 45,988 456 0.0% 0.0% 66 +9,834 27.2% Q4 2025 Feb 13, 2026
PROFUND ADVISORS LLC History New 38,054 377 0.01% 67 +38,054 New Q4 2025 Feb 06, 2026
MetLife Investment Management, LLC History New 35,721 354 0.0% 68 +35,721 New Q4 2025 Feb 12, 2026
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. History Added to 35,257 348 0.0% 0.0% 69 +23,804 207.84% Q4 2025 Feb 17, 2026
PANAGORA ASSET MANAGEMENT INC History No change 34,297 340 0.0% 0.0% 70 0 0.0% Q4 2025 Feb 13, 2026
PRICE T ROWE ASSOCIATES INC /MD/ History Added to 33,872 337 0.0% 0.0% 71 +21,907 183.09% Q4 2025 Feb 17, 2026
Graham Capital Management, L.P. History New 32,898 326 0.01% 72 +32,898 New Q4 2025 Feb 17, 2026
JPMORGAN CHASE & CO History Added to 29,861 296 0.0% 0.0% 73 +15,502 107.96% Q4 2025 Feb 11, 2026
Virtus Investment Advisers, LLC History New 27,230 270 0.07% 74 +27,230 New Q4 2025 Feb 17, 2026
WINTON GROUP Ltd History New 26,900 267 0.01% 75 +26,900 New Q4 2025 Feb 11, 2026
Susquehanna Portfolio Strategies, LLC History Added to 26,205 260 0.0% 0.0% 76 +3,296 14.39% Q4 2025 Feb 17, 2026
Mitsubishi UFJ Asset Management Co., Ltd. History New 26,209 251 0.0% 77 +26,209 New Q4 2025 Feb 03, 2026
IEQ CAPITAL, LLC History Reduced 24,692 245 0.0% 0.0% 78 -8,889 -26.47% Q4 2025 Feb 13, 2026
Cerity Partners LLC History Reduced 22,439 222 0.0% 0.0% 79 -1,151 -4.88% Q4 2025 Feb 11, 2026
Pale Fire Capital SE History Reduced 22,302 221 0.01% 0.02% 80 -11,348 -33.72% Q4 2025 Feb 13, 2026
OMERS ADMINISTRATION Corp History New 20,900 207 0.0% 81 +20,900 New Q4 2025 Feb 13, 2026
Soltis Investment Advisors LLC History No change 20,000 198 0.01% 0.01% 82 0 0.0% Q4 2025 Apr 02, 2026
NEW YORK STATE COMMON RETIREMENT FUND History Added to 19,887 197 0.0% 0.0% 83 +15,700 374.97% Q4 2025 Feb 12, 2026
MANUFACTURERS LIFE INSURANCE COMPANY, THE History New 19,147 190 0.0% 84 +19,147 New Q4 2025 Feb 13, 2026
CWM, LLC History Added to 18,953 188 0.0% 0.0% 85 +89 0.47% Q4 2025 Jan 26, 2026
SG Americas Securities, LLC History New 18,640 185 0.0% 86 +18,640 New Q4 2025 Jan 09, 2026
Vanguard Personalized Indexing Management, LLC History Reduced 16,436 163 0.0% 0.0% 87 -159 -0.96% Q4 2025 Feb 13, 2026
Police & Firemen's Retirement System of New Jersey History Added to 16,373 162 0.0% 0.0% 88 +10,333 171.08% Q4 2025 Feb 13, 2026
Persistent Asset Partners Ltd History New 16,025 159 0.07% 89 +16,025 New Q4 2025 Feb 17, 2026
CITIGROUP INC History Added to 15,293 151 0.0% 0.0% 90 +7,861 105.77% Q4 2025 Feb 13, 2026
ProShare Advisors LLC History New 14,752 146 0.0% 91 +14,752 New Q4 2025 Feb 06, 2026
INTECH INVESTMENT MANAGEMENT LLC History Added to 14,188 140 0.0% 0.0% 92 +2,317 19.52% Q4 2025 Feb 10, 2026
WEALTH ENHANCEMENT ADVISORY SERVICES, LLC History Added to 14,330 136 0.0% 0.0% 93 +86 0.6% Q4 2025 Jan 08, 2026
BRIDGEWAY CAPITAL MANAGEMENT, LLC History Reduced 13,400 133 0.0% 0.01% 94 -35,000 -72.31% Q4 2025 Feb 17, 2026
FMR LLC History Reduced 13,388 132 0.0% 0.0% 95 -45 -0.33% Q4 2025 Feb 17, 2026
SIMPLEX TRADING, LLC History Added to 13,031 129 0.0% 0.0% 96 +12,532 2511.42% Q4 2025 Feb 11, 2026
RAYMOND JAMES FINANCIAL INC History New 12,538 124 0.0% 97 +12,538 New Q4 2025 Feb 18, 2026
China Universal Asset Management Co., Ltd. History Added to 11,893 118 0.01% 0.01% 98 +2,427 25.64% Q4 2025 Jan 29, 2026
AlphaQuest LLC History New 11,726 116 0.01% 99 +11,726 New Q4 2025 Feb 09, 2026
GSA CAPITAL PARTNERS LLP History New 11,463 114 0.01% 100 +11,463 New Q4 2025 Feb 06, 2026
Ethic Inc. History Added to 11,449 113 0.0% 0.0% 101 +130 1.15% Q4 2025 Feb 03, 2026
COMMONWEALTH EQUITY SERVICES, LLC History Added to 11,234 111 0.0% 0.0% 102 +344 3.16% Q4 2025 Feb 12, 2026
XTX Topco Ltd History Reduced 11,144 110 0.0% 0.01% 103 -15,571 -58.29% Q4 2025 Feb 17, 2026
VOYA INVESTMENT MANAGEMENT LLC History New 10,976 108 0.0% 104 +10,976 New Q4 2025 Feb 12, 2026
LOS ANGELES CAPITAL MANAGEMENT LLC History Added to 11,555 108 0.0% 0.0% 105 +480 4.33% Q4 2025 Feb 11, 2026
Creative Planning History New 10,358 102 0.0% 106 +10,358 New Q4 2025 Feb 17, 2026
Caitong International Asset Management Co., Ltd History New 7,428 73 0.02% 107 +7,428 New Q4 2025 Mar 03, 2026
ROYAL BANK OF CANADA History New 6,721 67 0.0% 108 +6,721 New Q4 2025 Feb 17, 2026
Russell Investments Group, Ltd. History Added to 5,872 58 0.0% 0.0% 109 +3,615 160.17% Q4 2025 Feb 17, 2026
Legal & General Group Plc History Added to 5,631 55 0.0% 0.0% 110 +3,599 177.12% Q4 2025 Feb 09, 2026
Ameritas Investment Partners, Inc. History Added to 5,121 50 0.0% 0.0% 111 +2,734 114.54% Q4 2025 Feb 11, 2026
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM History Added to 3,884 38 0.0% 0.0% 112 +2,148 123.73% Q4 2025 Feb 17, 2026
Sterling Capital Management LLC History Added to 3,636 36 0.0% 0.0% 113 +1,903 109.81% Q4 2025 Feb 13, 2026
Mirae Asset Global Investments Co., Ltd. History Added to 3,547 35 0.0% 0.0% 114 +1,459 69.88% Q4 2025 Jan 26, 2026
Allworth Financial LP History New 3,386 33 0.0% 115 +3,386 New Q4 2025 Feb 05, 2026
NISA INVESTMENT ADVISORS, LLC History No change 2,765 27 0.0% 0.0% 116 0 0.0% Q4 2025 Jan 15, 2026
BESSEMER GROUP INC History New 2,380 24 0.0% 117 +2,380 New Q4 2025 Feb 05, 2026
AMALGAMATED BANK History Added to 1,982 20 0.0% 0.0% 118 +1,359 218.14% Q4 2025 Feb 05, 2026
GROUP ONE TRADING LLC History New 1,816 18 0.0% 119 +1,816 New Q4 2025 Feb 12, 2026
GF FUND MANAGEMENT CO. LTD. History Added to 1,434 14 0.0% 0.0% 120 +272 23.41% Q4 2025 Jan 27, 2026
Aquatic Capital Management LLC History New 1,085 10 0.0% 121 +1,085 New Q4 2025 Feb 17, 2026
Tower Research Capital LLC (TRC) History Reduced 826 8 0.0% 0.0% 122 -2,911 -77.9% Q4 2025 Feb 17, 2026
EverSource Wealth Advisors, LLC History No change 731 7 0.0% 0.0% 123 0 0.0% Q4 2025 Feb 06, 2026
Rockefeller Capital Management L.P. History Added to 700 6 0.0% 0.0% 124 +500 250.0% Q4 2025 Mar 16, 2026
US BANCORP \DE\ History New 555 5 0.0% 125 +555 New Q4 2025 Jan 30, 2026
PNC FINANCIAL SERVICES GROUP, INC. History Reduced 487 4 0.0% 0.0% 126 -186 -27.64% Q4 2025 Feb 06, 2026
Torren Management, LLC History New 321 3 0.0% 128 +321 New Q4 2025 Jan 30, 2026
Optiver Holding B.V. History No change 312 3 0.0% 0.0% 127 0 0.0% Q4 2025 Feb 17, 2026
Daiwa Securities Group Inc. History New 243 2 0.0% 130 +243 New Q4 2025 Feb 11, 2026
Larson Financial Group LLC History Added to 240 2 0.0% 132 +235 4700.0% Q4 2025 Feb 06, 2026
SIGNATUREFD, LLC History Added to 290 2 0.0% 0.0% 129 +112 62.92% Q4 2025 Jan 20, 2026
SBI Securities Co., Ltd. History Added to 217 2 0.0% 0.0% 133 +20 10.15% Q4 2025 Feb 03, 2026
IFP Advisors, Inc History No change 203 2 0.0% 0.0% 131 0 0.0% Q4 2025 Feb 06, 2026
True Wealth Design, LLC History No change 226 2 0.0% 0.0% 134 0 0.0% Q4 2025 Jan 08, 2026
Fortitude Family Office, LLC History No change 124 1 0.0% 135 0 0.0% Q4 2025 Jan 15, 2026
D1 Capital Partners L.P. History Closed out 0 0 0.07% -978,652 -100.0% Q3 2025 Nov 14, 2025
Palumbo Wealth Management LLC History Closed out 0 0 0.13% -61,276 -100.0% Q3 2025 Nov 10, 2025
Virtu Financial LLC History Closed out 0 0 0.02% -43,269 -100.0% Q3 2025 Nov 14, 2025
HRT FINANCIAL LP History Closed out 0 0 0.0% -21,510 -100.0% Q3 2025 Nov 14, 2025
Brevan Howard Capital Management LP History Closed out 0 0 0.0% -18,400 -100.0% Q3 2025 Nov 14, 2025
AXQ CAPITAL, LP History Closed out 0 0 0.04% -14,921 -100.0% Q3 2025 Nov 10, 2025
Scientech Research LLC History Closed out 0 0 0.03% -13,502 -100.0% Q3 2025 Nov 14, 2025
Arax Advisory Partners History Closed out 0 0 0.0% -4,551 -100.0% Q3 2025 Nov 14, 2025
Clearstead Advisors, LLC History Reduced 4 0 0.0% -300 -98.68% Q4 2025 Feb 09, 2026
OSAIC HOLDINGS, INC. History Reduced 57 0 0.0% -113 -66.47% Q4 2025 Feb 17, 2026
Farther Finance Advisors, LLC History New 57 0 +57 New Q4 2025 Jan 23, 2026
Rialto Wealth Management, LLC History New 53 0 +53 New Q4 2025 Jan 12, 2026
GAMMA Investing LLC History New 50 0 +50 New Q4 2025 Jan 05, 2026
Smartleaf Asset Management LLC History New 4 0 +4 New Q4 2025 Feb 13, 2026
ROTHSCHILD INVESTMENT LLC History New 1 0 +1 New Q4 2025 Feb 10, 2026
Sunbelt Securities, Inc. History No change 16 0 0 0.0% Q4 2025 Feb 20, 2026
Steward Partners Investment Advisory, LLC History No change 100 0 0 0.0% Q4 2025 Feb 12, 2026